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Doctor insights on: Platelet Function

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Can a platelet function disorder be a sign of vascular Ehlers Danlos?

Can a platelet function disorder be a sign of vascular Ehlers Danlos?

Usually not: In children with EDS, excessive bruising is often the presenting complaint to the pediatrician. Hematological studies including evaluation of clotting factors, platelet aggregation and bleeding time are usually normal in patients with EDS, Capillary fragility is usually cause of bruising in EDS.Generalized vascular fragility largely dominates the clinical picture. ...Read more

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I have a bleeding disorder (platelet function defect), and I want a tattoo, is it safe?

I have a bleeding disorder (platelet function defect), and I want a tattoo, is it safe?

Tattoo: Safe under experienced tattooer, as long as no infection occurs (clean instrument, gentle hands). ...Read more

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Platelet function test: collagen epinephrine normal, but ADP prolonged by 25 sec. Possible causes? Have normal CBC, PT, aPTT, CRP, d-dimer, comp met.

Platelet function test: collagen epinephrine normal, but ADP prolonged by 25 sec. Possible causes? Have normal CBC, PT, aPTT, CRP, d-dimer, comp met.

Aspirin exposure: This pattern of results could be from ingesting aspirin in some way. Aspirin (acetylsalicylic acid) is found in many things these days, including migraine meds, suppositories, fever/cough/cold relievers, & other OTC medications. Also, salicylate (salicylic acid), a prescription med for joint pain possible. Lastly, Plavix (clopidogrel) & other newer prescription meds aren't excluded. Happy hunting 4 u & ur doc! ...Read more

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Why is it that aspirin can prevent blood clots in arteries but not in veins? If it inhibits platelet function, why does it not do that everywhere?

Why is it that aspirin can prevent blood clots in arteries but not in veins? If it inhibits platelet function, why does it not do that everywhere?

It does: It does inhibit platelet function. It does inhibit clot formation in veins. Its just that venous clots aren't quite as serious an issue. We worry about clots in the arteries to your heart that can lead to heart attack or an artery to your extremity leading to cold leg or arm. People do get clots in their veins, they are called DVTs but they usually aren't fatal. ...Read more

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Explanations for elevated bilirubin ? (indirect high, direct normal)...also normal hemoglobin, low platelets, other liver function tests normal

Explanations for elevated bilirubin ?  (indirect high, direct normal)...also normal hemoglobin, low platelets, other liver function tests normal

Need more info: About 2-3% of otherwise normal people have elevated bilirubin, usually less than 5.0 mg/dL. Gilbert's disease is a usual cause and it despite disease in the name, it does not adversely affect a person's health. If you have any symptoms, it would be prudent to see your doctor. Consult this site for more info. http://www.mayoclinic.org/diseases-conditions/gilberts-syndrome/basics/definition/CON-20024904 ...Read more

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How can aspirin or any of nsaids affect the function of platelets ?

Platelet function: It affects platelet function by inhibiting cox-1-and subsequently affecting platelet aggregation. ...Read more

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Can you tell me how aspirin or any of nsaids affect the function of platelets ?

Can you tell me how aspirin or any of nsaids affect the function of platelets ?

Yes: Low-dose aspirin use irreversibly blocks the formation of thromboxane A2 in platelets, producing an inhibitory effect on platelet aggregation during the lifetime of the affected platelet (8–9 days). This acts to thin the blood by not allowing platelets to clump together. ...Read more

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What can cause high Active (holotranscobalamin) B12 levels in blood, when red & white cell & platelet counts, liver & kidney function are all normal?

What can cause high Active (holotranscobalamin) B12 levels in blood, when red & white cell & platelet counts, liver & kidney function are all normal?

It's just you: This test itself is not mainstream. It is experimental. A high value on a B12 is never a clinical concern. Reference ranges at real labs are set so that a few percent of healthy folks fall outside on either end. ...Read more