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Doctor insights on: Plasminogen Activity

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What compounds increase acetylcholinesterase activity?

Why do you ask?: Or ... "What are Organophosphates?" if you're playing Jeopardy. ...Read more

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What are tissue plasminogen activators used for?

What are tissue plasminogen activators used for?

Dissolve blood clots: These are proteins that when added to blood bind to clots and dissolve them. ...Read more

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Resuming exercise program: does muscle growth trigger angiogenesis?

Resuming exercise program: does muscle growth trigger angiogenesis?

It's complicated : Exercise can improve vascularity but it does not create the growth of new blood vessels. Angiogenesis is triggered by injury and cancer as well as during pregnancy. ...Read more

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What is the difference between plasma renin activity (pra) vs plasma renin concentration (prc)?

What is the difference between plasma renin activity (pra) vs plasma renin concentration (prc)?

See below:: Not all proteins are functionally active, especially in the case of enzymes. Discordance between renin concentration (prc) and renin activity (pra) allows detection of adrenal tumors. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmed/15080782. ...Read more

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What are the differences between recombinant tissue plasminogen activator and tissue plasminogen activator?

What are the differences between recombinant tissue plasminogen activator and tissue plasminogen activator?

Same aa sequence: tPA and its recombinant version (Activase) are identical with respect to the amino acid sequence. There have been reported some minor differences with respect to glycosylation of the protein, but this is well within the specifications of the cGMP production by the manufacturer. ...Read more

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Does creatine kinase always increase with muscle injury?

Does creatine kinase always increase with muscle injury?

Yes?: CPK or ck is elevated in conditions of the muscles ( aldolase, SGOT and ldh too). We use it as screening because it's sensitivity. It may elevate with cholesterol medicines, also with heart attacks and with rhabdomyolysis ( when it is too high in the thousands may cause renal damage). After injury to large muscles ck may get elevated. ...Read more

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Total calcium level 10.5( elevated by .5) total protein 8.8( elevated by .8)albumin 5.2(elevated by .2)phosphorus 2.3(decreased by .2) worrisome or no?

Total calcium level 10.5( elevated by .5) total protein 8.8( elevated by .8)albumin 5.2(elevated by .2)phosphorus 2.3(decreased by .2) worrisome or no?

Not really worrisome: These lab values are not all that abnormal and really in most cases are not to worry about as they are. It also depends on if you are having problems. If you had these drawn you must of had an order from your healthcare professional and you should also check with them and see if there is a problem that they are concerned about. Please check with them on the final decision. I hope this helped. ...Read more

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How are accidental physical activity and purposeful physical activity different?

How are accidental physical activity and purposeful physical activity different?

The difference..: is that one is physical activity performed incidentally while carrying out some task or errand. The other is physical activity which has been planned or intended, such as sports or exercise training. ...Read more

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Can taking bovine colostrum increase plasma immunoglobulin levels, thereby masking an underlying immunoglobulin deficiency by altering blood tests?

Can taking bovine colostrum increase plasma immunoglobulin levels, thereby masking an underlying immunoglobulin deficiency by altering blood tests?

Unlikely: Very thoughtful idea. Unfortunately, the bovine immunoglobins are too large to be absorbed from the intestine and would be digested by stomach and intestinal juices and enzymes. With use you would be providing body with raw materials for making your own immunoglobulins, but at a cost. Any "complete" proteins from eggs or milk could provide the same protein precursors and support good health. ...Read more

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What does Minimally reduced final aggregation in response to ADP with disaggregation(final aggregation approximate 30%) means in platelet aggrigation?

What does Minimally reduced final aggregation in response to ADP with disaggregation(final aggregation approximate 30%)
means in platelet aggrigation?

Platelet aggregation: The platelet test measures 2 phases - initial ability of platelets to plug leaks, and the secondary reaction of clumps of platelets to stick together (aggregate). Some drugs (like ASA or NSAIDS /ibuprofen) and other structural (genetic) defects can reduce secondary aggregation, which can increase risk of bleeding. Your result could be caused by taking 1 ASA weeks ago. ...Read more

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What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

What does a  low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more

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Does creatine kinase only rise with muscle injury?

Does creatine kinase only rise with muscle injury?

Muscle and Brain: Creatine kinase is present in skeletal muscle, heart, smooth muscle and brain and injury to any of these can cause elevation of this enzyme. ...Read more

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Does a high amount of physical activity raise your metabolism?

Does a high amount of physical activity raise your metabolism?

Yes: Physical activity is the best way to increase the overall metabolism in the body. Exercise as tolerated. Good luck ! ...Read more

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Does eating a meal alter the effects of abilify (aripiprazole)? Such as the 3-5 hour peak plasma levels, half-life, receptor binding, efficacy, kinetics? Curious...

Does eating a meal alter the effects of abilify (aripiprazole)? Such as the 3-5 hour peak plasma levels, half-life, receptor binding, efficacy, kinetics? Curious...

Abilify (aripiprazole): Usually there is not decreased effect when taking medications with food. Sometimes there are absorbed better. Abilify (aripiprazole) is usually prescribed together with an antidepressant to augment the effect. If taken at breakfast, it will not cause many side effects. Akathisia (restlessness of the legs) might be one of the few effects noticed. It is not very commonly reported. ...Read more

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SEROQUEL"quetiapine"raises prolactin levels, does that means protein synthesis is inhibited completely? or insignificantly?will it affect muscle growt

SEROQUEL"quetiapine"raises prolactin levels, does that means protein synthesis is inhibited completely? or insignificantly?will it affect muscle growt

Not likely : Quetiapine has the least propensity to raise prolactin levels (hyperprolactinemia) and therefore is likely to have little or insignificant effects on muscle growth. However, individuals vary in their response to medications and hyperprolactinemia is considered a rare side effect of Quetiapine. You could request labs to measure your prolactin levels. Great question! ...Read more

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Can vitamin E overdose increases anticoagulant activity of warfarin?

Can vitamin E overdose increases anticoagulant activity of warfarin?

YEs it can: Vitamin e has been shown to have anticoagulation effects. If you are taking warfarin and vitamin e, you should make sure your physician is aware. Remember- just because its a vitamin doesn't mean it has no downside. ...Read more

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Are creatinine kinase levels elevated during weight lifting?

Are creatinine kinase levels elevated during weight lifting?

Yes: Creatinine kinase can be high after a vigorous exercise routine. Maintaining good hydration is important to clear it from the body. ...Read more

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