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Doctor insights on: Plasminogen Activator Inhibitor 1

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Alteplase (Definition)

Alteplase is a clot buster which is a kind of ...Read more


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Please explain plasminogen activator.?

Please explain plasminogen activator.?

Clot Buster: Tissue plasminogen activator (tpa (alteplase)) is a chemical that triggers rapid breakdown of blood clots. It is used in stroke patients in an attempt to restore bloodflow to the brain before cells die, but the risk of bleeding makes it safe to use only in very specific circumstances. The most common reason for not qualifying for tpa (alteplase) is not getting to the er quickly enough- don't wait! time is brain! ...Read more

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Caring for an Elderly Loved One (Checklist)

Check your loved one's balance
once
Remove obstructions that could cause falls
once
Organize medications
monthly
Add railings for support
once
Dr. Jeffrey Unger Dr. Unger
<b>2</b> doctors agreed:
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Living with Type 1 Diabetes (Checklist)

Check your blood glucose 2 hours before and 2 hours after eating
once
Check with your doctor if your post-meal glucose is lower than your pre-meal glucose, as you may have hypoglycemia
once
Consider using a continuous sensor if you do not feel hypoglycemia symptoms
once
Use insulin pumps, as they can minimize your risk of hypoglycemia
once
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Chloride 94.9 L, Anion Gap 16.1 H, AST 58 H, Immature Granulocytes ABS 0.01 H,Ketones urine SMALL NEG. A, specific gravity urine <1.005 L. ?

Chloride 94.9 L, Anion Gap 16.1 H, AST 58 H, Immature Granulocytes ABS 0.01 H,Ketones urine SMALL NEG. A, specific gravity urine <1.005 L. ?

Plan: It's not clear what you want to know. To explain your abnormalities we need to know your primary condition. Your doctor who know your clinical symptoms and your previous results should explain it to you. ...Read more

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Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
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CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14. 7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14.  7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Difficult case: it is a complicated case obviously. first and foremost the infection has to be treated. i would suggest you to follow up with ID and oncologist very closely. importantly is to check if there is certain mutation like T315i mutation as this mutation is resistant to gleevec, sprycel, tasigna (nilotinib) - and should be treated with ponatinib or aurora kinase inhibitor etc. discuss with oncologist. God bless ...Read more

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What does Minimally reduced final aggregation in response to ADP with disaggregation(final aggregation approximate 30%) means in platelet aggrigation?

What does Minimally reduced final aggregation in response to ADP with disaggregation(final aggregation approximate 30%)
means in platelet aggrigation?

Platelet aggregation: The platelet test measures 2 phases - initial ability of platelets to plug leaks, and the secondary reaction of clumps of platelets to stick together (aggregate). Some drugs (like ASA or NSAIDS /ibuprofen) and other structural (genetic) defects can reduce secondary aggregation, which can increase risk of bleeding. Your result could be caused by taking 1 ASA weeks ago. ...Read more

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What is the function of prostaglandins, thromboxanes, and leukotrienes? :)

What is the function of prostaglandins, thromboxanes, and leukotrienes? :)

Platelets: They all contribute in the platelets function that are responsible in part in blood clotting. ...Read more

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Is there a test to detect autoantibodies against trpa1 channels and/or trp channels in general?

Is there a test to detect autoantibodies against trpa1 channels and/or trp channels in general?

Dysfunctional : Oxidation in brain. You are almost certainly vitamin b1 deficient and the commonest way to achieve that is through consumption of sugar and/or alcohol.Irrational rage is a major clue and is very dangerous because your actions are unpredictable. Forget the science and look for self responsibility toward diet. Experimental vitamin b1 deficient diets in1942 produced "psychosomatic" symkptoms. ...Read more

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Evista (raloxifene) estrogen receptor for uterine cancer?

Evista (raloxifene) estrogen receptor for uterine cancer?

Unclear Question?: These are somewhat unrelated questions which makes it difficult for me to address your question. Evista (raloxifene) is not used for treating cancer...It is sued for treatment/prevention of osteoporosis. Estrogen receptors are specialised protein receptors found in breast cancer.Uterine cancer has little bearing on either of the two references you have listed. ...Read more

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For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

Mild anemia: Assuming you've had no recent bleeding episodes, these findings could be seen in mild/early anemia of chronic disease. Hgb and Hct are only boarder line low, and iron panel appears within the reference range. Even something as simple as a particularly heavy period could cause mild anemia of this type, though. If you have a chronic medical illness, it could cause this type of anemia. ...Read more

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Could viibryd (vilazodone hydrochloride) potentially help ocd...And is it the strongest ssri ti hit serotonin receptors because of its dual action?

Could viibryd (vilazodone hydrochloride) potentially help ocd...And is it the strongest ssri ti hit serotonin receptors because of its dual action?

Choices, choices: The options could really drive anyone mad - not to mention an ocd sufferer. Some like it, some don't. Here's an opinion. You can find a wide range - just as you can for the other meds. What fits you is what matters. A link: http://chipur.Com/2011/03/01/viibryd-a-new-antidepressant-but-anything-exciting/ best! ...Read more

Dr. Brian Santin
75 doctors shared insights

Clot Buster (Definition)

Clot busters are a kind of ...Read more