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Doctor insights on: Plasminogen Activator Inhib Pai 1

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Dr. Ihab Ibrahim
12 doctors shared insights

Alteplase (Definition)

Alteplase is a clot buster which is a kind of ...Read more


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Is there a test to detect autoantibodies against trpa1 channels and/or trp channels in general?

Is there a test to detect autoantibodies against trpa1 channels and/or trp channels in general?

Dysfunctional : Oxidation in brain. You are almost certainly vitamin b1 deficient and the commonest way to achieve that is through consumption of sugar and/or alcohol.Irrational rage is a major clue and is very dangerous because your actions are unpredictable. Forget the science and look for self responsibility toward diet. Experimental vitamin b1 deficient diets in1942 produced "psychosomatic" symkptoms. ...Read more

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What does Minimally reduced final aggregation in response to ADP with disaggregation(final aggregation approximate 30%) means in platelet aggrigation?

What does Minimally reduced final aggregation in response to ADP with disaggregation(final aggregation approximate 30%)
means in platelet aggrigation?

Platelet aggregation: The platelet test measures 2 phases - initial ability of platelets to plug leaks, and the secondary reaction of clumps of platelets to stick together (aggregate). Some drugs (like ASA or NSAIDS /ibuprofen) and other structural (genetic) defects can reduce secondary aggregation, which can increase risk of bleeding. Your result could be caused by taking 1 ASA weeks ago. ...Read more

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I'm hebs ag negative with a high anti hbs antibody from vaccination. This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

I'm hebs ag negative with a high anti hbs antibody from vaccination.  This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

Yes: That sounds like lab error. Your hbsab would provide immunity; i'm assuming yoru hbcab (core) is negative; i wouldn't worry, talk to your doctor about a retest if you are concerned, but even if you were infected, there is no reason for treatment at this time. ...Read more

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My blood test results: total bilirubin: 1.41 h ast: 40 h alt: 100 h total alk phosphatase: 43 l serum total protein: 7.1 e.R. Said hepatitis?

My blood test results:
total bilirubin: 1.41 h
ast: 40 h
alt: 100 h
total alk phosphatase: 43 l
serum total protein: 7.1

e.R. Said hepatitis?

Let's try this...: I have only a little bit of the story you've shared. Perhaps it's time to see whether the ast and alt get back to normal after two weeks off alcohol and any not-totally-necessary meds you may be taking. If so, this is the start of a healthier life after alcohol. If not, the workup for virus infections, iron overload, wilson's, autoimmunity & need for exercise can begin. Good luck. ...Read more

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My serum triglycerides is 210 serum cholesterol 212 HDL 52.5 LDL 124 vldl 42 n non HDL 160 please guide me dat in which areas i m at risk n reasons?

My serum triglycerides is 210 serum cholesterol 212 HDL 52.5 LDL 124 vldl 42 n non HDL 160 please guide me dat in which areas i m at risk n reasons?

See below: Borderline lipids. Need to know your age and other medical problems like exisent heart disease or diabetes to determine your risk with those lipid levels. ...Read more

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Triglycerides 453 hi. Glucose 132H.Bun 26H. Hemoglobin 11.7 low. Hematocrit 37.5 L. Mchc 31.2 L. RDW 15.5 H. MICROALB CREAT 240 H. VitD 22 L. Father60 and Diabetic . Rest of Cbc and othere normal. What could this be?

Triglycerides 453 hi. Glucose 132H.Bun 26H. Hemoglobin 11.7 low. Hematocrit 37.5 L. Mchc 31.2 L. RDW 15.5 H. MICROALB CREAT 240 H. VitD 22 L. Father60 and Diabetic . Rest of Cbc and othere normal. What could this be?

Need good care: You need to be under the care of a competent physician who can keep your diabetes under control and find the cause of your anemia, which i suspect is due to iron deficiency from blood being lose somewhere. We can't solve it here. If you have a specific question, let us know. ...Read more

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Pat.With dm and ht present with ischemic cva(> 1/3 MCA distribution) ECG show af. When we start anticoagulant?

Pat.With dm and ht present with ischemic cva(> 1/3 MCA distribution)  ECG show af. When we start anticoagulant?

Good question: There is multitude of factors affecting anticoagulant therapy, patient's current physicians will analyze these factors and they should make the decision. Good luck. ...Read more

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Wbc 13.2 RBC 4.73 hemoglobin 10.2 hematocrit 33.8 mvc 72 MCH 21.6 mchc 30.2 RDW 16.2 platelets 816, 000.Thoughts?Should i be worried with the platelets

Wbc 13.2 RBC 4.73 hemoglobin 10.2 hematocrit 33.8 mvc 72 MCH 21.6 mchc 30.2 RDW 16.2 platelets 816, 000.Thoughts?Should i be worried with the platelets

Probably reactive: You are anemic and the numbers are suspicious for iron deficiency. If you are a healthy 34 year-old who menstruates regularly, you could easily be low in iron. The plaelet count is very high, but is likely reacting to the low iron and should come down if it is replaced. The elevated white cells (WBC) is not as easy to understand. Inflamation, infection, other? Could use more info. Good luck. ...Read more

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My beta globlin is .97 normal to 1.2 gama is 1.69 normal is to1.74 which mean gama large than betacould it myloma? In spectra gama apper wide range

My beta globlin is .97 normal to 1.2
gama is 1.69 normal is to1.74 which mean gama large than betacould it myloma?  In spectra gama apper wide range

Within normal range: The result is within normal range. Do you see any monoclonal protein is detected on the spep? Do you have immunofixation electrophoresis done? Discuss the result further with your doctor. ...Read more

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Does beta blockers prevent vf in myocarditis ?

Does beta blockers prevent vf in myocarditis ?

Ventricular fibrilla: Antiarrhythmic medications and antiheart failure medications can decrease the probability of ventricular fibrillation but no medication is 'preventative'. ...Read more

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Age 39 Smoker Male, Blood Sugar Normal; TIA Stroke 1 week back.Taking Ecosprin AV75. MRI Brain: Tiny ischemic foci on both froantal lobe. Any risk?

Age 39 Smoker Male, Blood Sugar Normal; TIA Stroke 1 week back.Taking Ecosprin AV75. MRI Brain: Tiny ischemic foci on both froantal lobe. Any risk?

Yes..serious stroke: Your info suggests brain vascular problems that are causing ischemia (reduced blood flow to brain tissue) which until now has been mild or transient but unless you quit smoking , among other preventive measures, you risk more serious ischemic brain injury or stroke ...Read more

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Help me, 59yrf-dercum's disease, lymphedema, ans disorder, heart disease- mi x3, 10+herniated discs, autoimmunity, gastroparesis, duodenitis w nodule?

Help me, 59yrf-dercum's disease, lymphedema, ans disorder, heart disease- mi x3, 10+herniated discs, autoimmunity, gastroparesis, duodenitis w nodule?

Too many issues here: If you do have all these listed problems, you need a good internist to take care of you and guide you further. Health matters get complicated if you truly have more than one or 2 ailments and you need long term care for any such diseases that are chronic in nature. You need a good primary care doctor to guide you for the long term. ...Read more

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Been diagnosed with peripheral neuropathy blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

Been diagnosed with peripheral neuropathy   blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

PlasmaCellDIsorder: May have plasma cell disorder/multiple myeloma. Plasma cells are a type of white blood cells that produces immunoglobulin(antibodies). Multiple myeloma is a cancerous or excessive proliferation of these plasma cells which may lead to excessive high levels of calcium/bone pain/renal failure/anemia (low blood counts). Need to see hematologist (blood doctor specialist). ...Read more

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Are these labs cause for concern? Calcium 8.7 L Creatinine 0.61 L Anion Gap 13.9 H Epithelial Cells- Many WBC-10-20

Are these labs cause for concern? Calcium 8.7 L
Creatinine 0.61 L
Anion Gap 13.9 H
Epithelial Cells- Many 
WBC-10-20

May be WBC: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, I trust the WBC 10-20 was in urine. If so, it should be repeated with proper urine collection of mid-stream specimen, after cleaning the external genitalia. Your doctor can advise on proper collection technique. Others are okay. ...Read more

Dr. Brian Santin
73 doctors shared insights

Clot Buster (Definition)

Clot busters are a kind of ...Read more