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Doctor insights on: Plasmapheresis Multiple Sclerosis

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Why plasma exchange is not curative for multiple sclerosis? thanks for answering

Why plasma exchange is not curative for multiple sclerosis? thanks for answering

Good question: plasmaphereis (plasma exchange) is used when steroids fail in controlling acute relapses of the disease.Why is it not curative: because it is an immune system dysfunction, I.e. the plasma exchange will help for a short period, the the immune system will act again necessitating another treatment, so no once and for all treatment with plasma exchange. Long term management requires immuno-modulatin ...Read more

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Plasma Exchange (Definition)

Plasmapheresis(plasma exchange) is a process involving the following steps: 1.Whole blood is withdrawn from the person. 2.The liquid portion or plasma is removed from the blood and replaced. 3.The blood, with all its red and white blood cells, is transfused back into the person. Usually made by an automated procedure and in precense of especialized healthcare ...Read more


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How can plasma exchange help multiple sclerosis patients?

How can plasma exchange help multiple sclerosis patients?

Relapse Rx: Plasmapheresis is usually reserved for patients with relapsing remitting ms who are not responding to either steroids or acth, and is typically third line. Important to successfully reverse all relapses as 50% of untreated relapses will not reverse and provide added disability. Since there is risk with plasma exchange, need to work with a very experienced treatment team. ...Read more

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Treatment of multiple sclerosis is for life or temporary taking s.c injection of betaferon?

Treatment of multiple sclerosis is for life or temporary taking s.c injection of betaferon?

Need chronically: Some advice, there are pills available, but where you live, might be tough to get. Nonetheless, do not miss your injections, and add Vitamin D-3 about 5000-10000 units per day. We do not have a clear idea when to stop the MS meds, and in those older patients who I have stopped, a few have had relapses. Stay tuned, drugs to be used differently are on the horizon. (even Lemtrada) ...Read more

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All test Negative. No multiple Sclerosis! Who or where can I go to find out why I'm having problems bending my leg. NO PAIN!!! ?

All test Negative. No multiple Sclerosis! Who or where can I go to find out why I'm having problems bending my leg. NO PAIN!!!
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Painless leg problem: I'm a bit confused. You state "No multiple Sclerosis!" but in your Clinical Findings: Conditions, you list "Multiple sclerosis". You also didn't describe where you're having painless difficulty bending your leg: hip? knee? ankle? My suggestion is to have your Family Doc refer you to Sports Med specialist, Rheumatologist, Orthopedic surgeon & even Neurologist esp if MS. Have u had EMG/NCV? Biopsy? ...Read more

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I have multiple sclerosis & the symptoms of diabetes are so similar how do I know if i'm a diabetic? My dr. Refers everything to multiple sclerosis.

I have multiple sclerosis & the symptoms of diabetes are so similar how do I know if i'm a diabetic? My dr. Refers everything to multiple sclerosis.

Easy: The test for diabetes is simple - it is just a blood test. It is important not to attribute everything you experience to ms. However, it is possible your doctor has already done some additional testing and has ruled-out diabetes. Many patients are not aware of all the tests that are run when they go to the lab and have blood drawn. Just ask your doctor. ...Read more

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I'm scared I have multiple sclerosis?

I'm scared I have multiple sclerosis?

Need to know more: Will really need to know more about what your symptoms are. Initially, you should discuss your concerns with your primary care physician. Then an appropriate a referral to a neurologist will allow a more definitive diagnosis for you.Multiple sclerosis is treatable at the present time with multiple medications and ensure an excellany quality of life. ...Read more

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What are the dangers, if any, of taking cycles or "gear" for bodybuilding if that person had multiple sclerosis? I'm just curious.

Not simple: Bodily temperature elevation, from vigorous exercise, may result in a pseudo exacerbation, with amplification of prior symptoms which can reverse with cooling. But exercise is of value for ms patients, just needs to be paced. Also, depending upon the patients debility, exercise should be designed to prevent harm secondary to weakness, or imbalance/incoordination. ...Read more

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Why are "family doctors" answering multiple sclerosis questions?! I have spotted inaccurate info being given. Only a neuro answer? 's

Why are "family doctors" answering multiple sclerosis questions?! I have spotted inaccurate info being given. Only a neuro answer? 's

Part of a team: Your family doctor is usually the doc who makes the referrals and is often the one who helps treat complications, such as urinary tract infections, fatigue, associated injuries, medication reactions, and he/she keeps open the communication lines between different specialties. Coordination of medical care is critcal these days. ...Read more

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Dr. What if on last MRI the lesions of multiple sclerosis disappear? is that means that I'm healed ?yeah I'm the patient

Dr. What if on last MRI the lesions of multiple sclerosis disappear? is that means that I'm  healed ?yeah I'm the patient

Comments: The MRI lesions in MS do NOT typically "disappear", and if this has happened, you did NOT have MS. Get a neurological consultation, but under the circumstances truly doubt your original diagnosis. ...Read more

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Is multiple sclerosis hereditary?

Is multiple sclerosis hereditary?

Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest. ...Read more

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Who discovered multiple sclerosis?

Who discovered multiple sclerosis?

Charcot: The French neurologist Charcot is credited with identifying MS as a distinct entity for the first time. ...Read more

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Could you cure multiple sclerosis?

Could you cure multiple sclerosis?

No cure at this time: It is difficult to develop a cure when the cause of a condition is not fully understood. There seem to be several factors that contribute to the development of MS but there is no ONE gene or ONE virus that has been implicated as a direct cause. Rather, the interaction of genetic susceptibility and infectous and/or environmental factors seem to result in dysregulation of the immune system. ...Read more

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How is multiple sclerosis diagnosed?

Detective Work: No one diagnostic study can stand alone to conclusively diagnose ms. A neurologist must be a detective, hunting out clues from symptoms suggesting abnormal function in the brain or spinal cord white matter, of appropriate duration (greater than 24 hours) coupled with abnormalities on examination. Mri, spinal fluid, and certain blood tests. This information can help exclude MS mimickers. ...Read more

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What makes you get multiple sclerosis?

What makes you get multiple sclerosis?

Not fully understood: Multiple sclerosis is a very complex disease. There is a large collection of research identifying certain genes (most governing control of the immune system) as both increasing risk and potentially protective against MS (based on studies of populations). Environmental and hormonal factors may also play a role in individuals with a background genetic risk. ...Read more

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How is multiple sclerosis transmitted?

Genes: Ms has been shown to be associated with mutations in a number of genes, the majority of which appear to regulate the immune system. Among first degree relatives, the risk of ms is increased, but absolute risk is low. Other factors weigh in to the development and expression of this disease other than strictly genetic predisposition. ...Read more

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What is a legent for multiple sclerosis?

What is a legent for multiple sclerosis?

What is a legent?: Not sure what legent means. Some people ask about lesion, or legend, or ligand, are any of those what you mean? Feel free to ask again, asking questions is free. ...Read more

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How to know if I have multiple sclerosis?

How to know if I have multiple sclerosis?

??: Why do you inquire about this? A diagnosis of MS typically requires specialized testing performed by a neurologist. ...Read more

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What are some effects of multiple sclerosis?

What are some effects of multiple sclerosis?

Reputable resources: I suggest that my patients spend time exploring the following websites: NMSS.org MSAA.org You may also get information from the MS societies in the UK and Canada. Please understand that the phenotype of MS is highly variable. Some patients are seemingly unaffected and others are profoundly disabled. Do not assume that the person with MS will experience all of the symptoms you read about. ...Read more

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How could multiple sclerosis affect someone?

How could multiple sclerosis affect someone?

Impact: Learning disabilities multiple injuries social isolation dependent personality difficulty getting jobs poor grades in school / college side effects from medications may not be able to drive disability depression and many more. ...Read more

Dr. Tiffanie Noonan
15 doctors shared insights

Plasmapheresis (Definition)

It is a procedure whereby blood is taken out of the patient the blood cells are separated from the liquid or plasma and then the blood cells are given back to the patient. This is often used to treat disorders of the immune system. Antibodies from the immune system are ...Read more


Dr. Amrita Dosanjh
3 doctors shared insights

Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more