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Doctor insights on: Plasma Cells In Bone Marrow Biopsy

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4%plasma cells in bone marrow biopsy-how serious is it?

4%plasma cells in bone marrow biopsy-how serious is it?

Can be normal.: Up to 5% is normal as long as they are not "monoclonal" meaning derived from a cell. If monoclonal then a bone cancer called myeloma needs to be ruled out. If no bone disease, anemia, high calcium or kidney disease answer is MGUS, a pre-cancerous condition with low risk of progression (less than 1% per year). ...Read more

Dr. Pen Hou
117 Doctors shared insights

Bone Marrow Biopsy (Definition)

A bone marrow biopsy is taken from the pelvic bone. A coring needle is advanced into the bone, which allows one to extract a sliver of the bone marrow, the red part of the bone. It is cut and viewed under a microscope. A bone marrow aspirate, obtained with a syringe, is usually bone at the same time. These are done to diagnose blood problems or to check for tumors in ...Read more


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Multiple myloma specialist needed pls help me confusing reports low m spike below 1 no crab but 14 percent plasma cells in Bone marrow biopsy worried?

Multiple myloma specialist needed pls help me confusing reports low m spike below 1 no crab but 14 percent plasma cells in Bone marrow biopsy worried?

Might be myeloma: Your plasma cells >10% in the bone marrow biopsy mean either smoldering myeloma or active myeloma. If you have elevated calcium, anemia, renal insufficiency or lytic bone lesions, I'm sorry to say you have myeloma. If not, you have smoldering myeloma. Go to this link for more info: http://www. Nccn. Org/patients/guidelines/myeloma/index. Html ...Read more

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Non-itchy/raised brown spots on back, spread to chest & stomach. Biopsy shows overproduction of plasma cells; bone marrow biopsy normal. Next steps?

Non-itchy/raised brown spots on back, spread to chest & stomach. Biopsy shows overproduction of plasma cells; bone marrow biopsy normal. Next steps?

Characterize cells: What you report is not definitive. Is this a plasma cell-rich inflammatory process, or is it a multifocal plasma cell tumor? The pathologists can investigate the cells to determine if they are of mixed clonal origin (benign) or monoclonal (meaning all derived form a single parent, usually a sign of a cancer). This can be done by evaluating the surface light chain expression. ...Read more

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Hi pls gve me insight in a bone marrow biopsy results which says 15 percent plasma cells?

Hi pls gve me insight in a bone marrow biopsy results which says 15 percent plasma cells?

Plasma Cells: Plasma cells are a normal component of bone marrow. A higher percentage than normal can indicate certain conditions such as multiple myeloma or MGUS. It is important to understand that any test needs to be interpreted in the context of other clinical findings. Discuss these results with your physician to figure out the diagnosis. ...Read more

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Wat does cd 5;21;23 b cell lymphocyte present in bone marrow biopsy indicate. I have pancytopenia nd spleenohepatomegaly?

Wat does cd 5;21;23 b cell lymphocyte present in bone marrow biopsy indicate. I have pancytopenia nd spleenohepatomegaly?

CD5 and CD23: Positivity are characteristic of chronic lymphocytic leukemia and mantle cell lymphoma. Cll is more common. Low blood counts and enlarged liver and spleen could be seen in both diseases. ...Read more

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Does the presence of bright cd8 t-cells on bone marrow biopsy indicate cancer?

Does the presence of bright cd8 t-cells on bone marrow biopsy indicate cancer?

Not really: Presence of cancer cells is only indication of cancer no other cells., to call it a cancer you have to see cancer cells nothing else. Cd-8 t cells are seen in viral infections also. These cells are some times seen surrounding the tumor or inside the tumor which is a good prognostic sign presence of immunity, body is fighting the cancer. ...Read more

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Is a bone marrow biopsy painful?

Yes and no: Any biopsy will be painful but in the hands of an experienced doctor and proper sedation (local novocaine) it can be a much more tolerable process. Pain killers such as tylenol (acetaminophen) afterwards for 24-58 hours can be a help too. ...Read more

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What amount is a bone marrow biopsy?

What amount is a bone marrow biopsy?

Bone marrow biopsy?: I am not clear what you are asking--do you want to know how much bone marrow is removed during a bone marrow biopsy?
Generally, 5-15 cc's of marrow is removed during a bone marrow aspiration and then a 2-3 cm small piece of the bone marrow is removed for the biopsy.

If you were trying to get other information please add a more detailed question. ...Read more

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Does a bone marrow biopsy cause pain?

Does a bone marrow biopsy cause pain?

Yes: A bone marrow biopsy unfortunately can be a painful procedure. It is only performed when the benefits outweigh the risks, however. ...Read more

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When do you need a bone marrow biopsy?

Blood disorders: A number of blood disorders like undiagnosed anemia, leukemia, high red cell count, low white cell or platelet count may warrant a bone marrow biopsy. See this site for more info.

http://www. Webmd. Com/cancer/bone-marrow-aspiration-and-biopsy ...Read more

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Can getting a bone marrow biopsy hurt?

It will hurt: Even with a local anesthetic and some sedation, you can expect a fair amount of pain. Be brave and remember that it's being done to promote your improved health. ...Read more

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What is a bone marrow biopsy done for?

What is a bone marrow biopsy done for?

Bone marrow biopsy: Hi, Bone Marrow biopsy is usually performed when a blood cell disorder is suspected, blood cell disorders are: Leukemia, aplastic anemia, multiple mylemoa and etc and some infectious processes. ...Read more

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What makes an a bone marrow biopsy abnormal?

What makes an a bone marrow biopsy abnormal?

Change in components: A bone marrow biopsy in a normal person will find the pattern of cells most often seen in a healthy person of that age. This would include red cells and their precursers (builders), white cells & precursers, platelet precursers & others. In illness, the pattern changes, and some or all may be abnormal. Tumor cells may take over every space& or few if any normal cells may be seen. ...Read more

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How painful is a bone marrow biopsy typically?

It depends: Some people have a higher pain tolerance than others. Even at the hands of the most skilled physician, a bone marrow biopsy is at least uncomfortable. ...Read more

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Why could someone require a bone-marrow biopsy?

Why could someone require a bone-marrow biopsy?

Many Indications: Bone marrow biopsy is most useful in diagnosis and staging of blood cancers (leukemia, lymphoma, multiple myeloma, etc). Also indicated for evaluating unexplained anemia, leukopenia, thrombocytopenia, pancytopenia, or unexplained elevated blood counts. It is also useful for fever of unknown origin, or as a confirmation that bone marrow transplantation is successful. ...Read more

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Where on the body is a bone marrow biopsy done?

The hip: Biopsies are taken from the upper back portion of the hip. Occasionally, if a suction aspiration is needed, a breastbone puncture can be used. ...Read more

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Does getting a bone marrow biopsy typically hurt?

Depends: If your receive conscious sedation, you will not have noticeable pain during the procedure. Afterward, you may have pain for a day or so unless there is an untoward complication. I had one and it hurt minimally for 24 hours. I had conscious sedation. ...Read more

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How can you make a bone marrow biopsy less painful?

Sedation: Light sedation can be used, in addition the soft tissues should be numbed to the periosteum, the outer layer of bone. ...Read more

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What can I do about pain in the bone marrow biopsy?

What can I do about pain in the bone marrow biopsy?

Bone marrow biopsy: If it is done after adequate local anesthesia is used with lidocaine, it should not hurt, maybe little pressure or discomfort at site. After procedure you can take an aleve, advil or tylenol (acetaminophen) to alleviate the pain. ...Read more

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What is the probablity of a clean bone marrow biopsy?

Clarify your questio: In what setting? It depends on what disease, how long you have that, do you have systemic symptoms etc? For more indolent disease - like cll for instance- the chance to see involvement to the bone marrow is pretty high as the disease may have been there for years. For acute leukemia- definitely bone marrow will be abnormal. ...Read more

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Is there any disadvantage of having bone marrow biopsy?

Is there any disadvantage of having bone marrow biopsy?

Small risk: There is always risk involved in any procedure. Some have greater risk than others. Generally speaking, bone marrow biopsies are low risk, but your hematologist would be the best person to assess whether the risk outweighs the potential benefit, which is the real question. ...Read more

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How long could the pain last after a bone marrow biopsy?

Short term: Should be no more than a few days; and that is on the longer side of the estimate. ...Read more

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How long does after a bone marrow biopsy does hurt it for?

Not long: See my previous answer. Usually a day or so unless there were complications. If longer than a couple of day, I would call the doctor and discuss. There could be bleeding at the site with a hematoma or potentially an infection. A bruise is to be expected and can cause some soreness. ...Read more

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Could a bone marrow biopsy cause me problems later in life?

No: There are no long term detriments to a bone marrow biopsy. Although rare, an infection is possible but this still should not cause any long term issues. ...Read more

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What is the definition or description of: bone marrow biopsy?

Needle biopsy.: A bone marrow biopsy is taken from the pelvic bone. A coring needle is advanced into the bone, which allows one to extract a sliver of the bone marrow, the red part of the bone. It is cut and viewed under a microscope. A bone marrow aspirate, obtained with a syringe, is usually bone at the same time. These are done to diagnose blood problems or to check for tumors in people with known cancer. ...Read more

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Could you explain what is a bone-marrow biopsy used to treat?

To diagnose not to: Treat. Bone marrow biopsy is a diagnostic process for disorders of blood and sometimes bone and some cancers. It is not a treatment for any disease. See this site for more info.
http://www. Nlm. Nih. Gov/medlineplus/ency/article/003934.htm. ...Read more

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How long should I experience pain after a bone marrow biopsy?

A few weeks usually: Normally- you may feel some tenderness for a week or more after your bone marrow exam. Ask your doctor about taking a pain reliever, such as Acetaminophen (tylenol, others). Some people have pain that will last longer. If you are getting more and more pain then have it checked out. ...Read more

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How long does it take to get results of a bone marrow biopsy?

Typically: 2 to 3 working days. A rapid preliminary result can be available in hours with a concern for acute leukemia. If a reference lab is used it can take 7-10 days. ...Read more

Dr. Linda Callaghan
2 Doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more