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Doctor insights on: Plaquenil Swelling And Rash On Ankle Joints

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I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

I have  recurring flares of  rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back.  My ANA is 6:40.  I'm on plaquenil. Why are all my other antibodies neg for lupus?

Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more

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Dr. David Schleimer
1,498 doctors shared insights

Swelling (Definition)

Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks). Swelling can occur all over the body (generalized) or only in one part ...Read more


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Had red rash all over body.4 days i'm on 3 different anitihistamin.Now joint stiffness, swelling feet, ankles, hands, wrist.What could this be?

Had red rash all over body.4 days i'm on 3 different anitihistamin.Now joint stiffness, swelling feet, ankles, hands, wrist.What could this be?

Food Allergies?: Three antihistamines you are taken, are they prescription antihistamins or you are taking over the counter like claritn, benadryl, (diphenhydramine) Allegra or zyrtec.And do you know what you are allergic to. If not already i will recommend you consult an allergist.Food allergies can cause rash and swelling of joints as well and rheumatoid arthritis can cause rash. So consult your md/allergist/rheumatologist, some one. ...Read more

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Lower leg rash along with swelling and joint pain?

Lower leg rash along with swelling and joint pain?

See a physician: Many possibilties exist. Your situation is one that needs a physician evaluation rather urgently. A good history, physical exam, lab work and possible drainage of the joint swelling will likely produce the diagnosis or at least narrow the possibilities and allow for appropriate treatment measures. ...Read more

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My dr won't diagnose me, but my joint pain/stiffness, fatigue, dry eyes/mouth, rashes, raynauds & rashes improve on plaquenil (hydroxychloroquine). What does that mean?

Autoimmune disease: You probably have an autoimmune disease that does not meet criteria fully for diagnosis. With time, criteria may be met and a diagnosis may br given. If you are getting better with treatment, then a formal diagnosis is not critical. ...Read more

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I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more

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How do I treat painful swelling joints especially my ankles?

How do I treat painful swelling joints especially my ankles?

First: You find the cause ten you will get treatment. Swelling could be caused by many different things like circulatory problems, to much alcohol or salt and being over weight. ...Read more

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Dr. Stratos Christianakis
1,189 doctors shared insights

Joints (Definition)

Joints are parts of the body, formed by the cartilage-covered ends of bones plus the strong, flexible ligaments that attach the bones to one another. Movements at the joints in the body allow the different parts of the body to move in ...Read more


Dr. John Chiu
2,616 doctors shared insights

Skin Rash (Definition)

A skin rash is a symptom in which a person has changes on part or all of his skin, such as color changes, bumps, blisters, oozing, peeling, ...Read more