Doctor insights on:
Plaquenil Effect Urine
I'm only 35 and can't hold in my urine. I'm on plaquenil, amitiza, (lubiprostone) meloxicam and myfortic. Can any of these be the cause of my incontinence ?
Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more
Sle pt w/ flare in july. Hosp. Had dark brown urine but dr said kidneys ok. Recently GFR is 43. Could this be from plaquenil/cellcept/pred or lupus?
Nothing safer: Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. So other meds like Imuran and CellCept (mycophenolate mofetil) also reduce flares, but also increases infection. ...Read more
Plaquenil (hydroxychloroquine): Plaquenil (hydroxychloroquine) has many side effects. Some common ones include dizziness, abdominal pain, headache, nausea, diarrhea, itching, and sensitiviy to sun. More serious side effects which are more rare include certain types of anemia, muscle pain, and liver problems, among others. Despite the fact that what you describe is not officially under it's side effect profile, it still could be causing your symptoms. ...Read more