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Doctor insights on: Piperacillin

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Dr. Caroline Vitale
63 doctors shared insights

Piperacillin (Overview)

Piperacillin sodium is a fourth generation cephalosporin which is a kind of cephalosporin type drug (anti-bacterial drug, antibiotic and antimicrobial).


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What does the body do with the piperacillin?

What does the body do with the piperacillin?

Excrete it: Piperacillin is excreted from the body in the urine by the kidneys and in the bile by the liver. With normal kidney function 1/2 of the drug is excreted every hour. ...Read more

Dr. Caroline Vitale
63 doctors shared insights

Piperacillin (Overview)

Piperacillin sodium is a fourth generation cephalosporin which is a kind of cephalosporin type drug (anti-bacterial drug, antibiotic and antimicrobial).


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How long does it take for piperacillin/tazobac , 3.375g IV drip to become effective?

How long does it take for piperacillin/tazobac , 3.375g IV drip to become effective?

Depends on what is..: Meant for effective and what is being treated and where the infection is. Usually with 12-24 hours, objective criteria of improvement such as decreasing temperature, decreasing white blood cell count and improvement in symptoms. ...Read more

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What does the body do with the piperacillin?

Excrete it: Piperacillin is excreted from the body in the urine by the kidneys and in the bile by the liver. With normal kidney function 1/2 of the drug is excreted every hour. ...Read more

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How long does it take for piperacillin/tazobac , 3.375g IV drip to become effective?

Depends on what is..: Meant for effective and what is being treated and where the infection is. Usually with 12-24 hours, objective criteria of improvement such as decreasing temperature, decreasing white blood cell count and improvement in symptoms. ...Read more

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If you are allergic to penicillin will you be allergic to piperacillin?

If you are allergic to penicillin will you be allergic to piperacillin?

We assume yes: We assume yes but since many people's allergies are not correct - eg they had coincidental rash while on penicillin, etc it may or may not be true. Since we almost never need to use penicillin so if you tell us you are allergic we usually will not chance a reaction. ...Read more

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How does alcohol affect zosyn (piperacillin and tazobactam)?

How does alcohol affect  zosyn (piperacillin and tazobactam)?

No: No problem taking penicillin class antibiotics with alcohol but keep it to a minimum if at all. If you have a significant infection it would be best to abstain until the infection has resolved. ...Read more

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Why give a patient zosyn (piperacillin and tazobactam) if allergc to penicilln?

Why give a patient zosyn (piperacillin and tazobactam) if allergc to penicilln?

You shouldn't: You shouldn't. Zosyn (piperacillin and tazobactam) contains the penicillin class antibiotic piperacillin which would have a very high likelihood for cross allergenicity with other drugs of the penicillin class. ...Read more

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Do they give a patient zosyn (piperacillin and tazobactam) when allergc to penicilln?

Do they give a patient zosyn (piperacillin and tazobactam) when allergc to penicilln?

Generally no: But it depends on the allergy and the indication. If the allergy to penicillin is mild and the indication is for a life threatening illness, then zosyn (piperacillin and tazobactam) (piperacillin/tazobactam) can be cautiously used. ...Read more

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Piperacillin/tazobactam IV will kill klebsiella pneumonia bacteria?

Piperacillin/tazobactam IV will kill klebsiella pneumonia bacteria?

It may but...: It depends on the resistance profile of specific strain of klebsiella. Many strains acquired in the 'community' are very sensitive to almost all antimicrobials except penicillin and Ampicillin and certainly sensitive to piperacillin/tazobactam. However, especially when acquired in a hospital, klebsiella can be quite resistant to therapy including pip/tazobactam. ...Read more

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For diabetic ulcer foot infections what's good? Zosyn (piperacillin and tazobactam)?

For diabetic ulcer foot infections what's good? Zosyn (piperacillin and tazobactam)?

Yes: Zosyn (piperacillin and tazobactam) is one of several antibiotics that is effective as empiric treatment for diabetic foot infections. Wound cultures guide definitive antibiotic treatment. You need to keep your diabetes under tight control to prevent development of peripheral vascular disease and neuropathy which predispose to serious diabetic foot infections and osteomyelitis. ...Read more

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Peritonitis, tried zosyn (piperacillin and tazobactam) and now meropenem, white blood count still high and no change in numbers. How long till it starts working?

Peritonitis, tried zosyn (piperacillin and tazobactam) and now meropenem, white blood count still high and no change in numbers. How long till it starts working?

See below: Your antibiotic treatment for bacterial peritonitis has been appropriate. You should have a repeat ct scan of the abdomen and pelvis to look for an undrained abscess that can be drained and cultured. Knowing the cause of the peritonitis and the diagnostic studies to date would be important in determining treatment recommendations. Hope you get better soon. ...Read more

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Am I dying?

Am I dying?

We all are: A 3-word question with no details... well, life is short on Earth, regardless of whether a person lives 3 days, 3000 days, or 30,000 days. It is not length of one's life that matters, but the quality of the life lived. The goal is not to live a long life, but to live a good life. Even if a person makes it all the way to age 82, that's only 30,000 days. ...Read more

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I have cold?

I have cold?

Symptoms?: The most common symptoms of a cold are sneezing, running nose, congestion and scratchy throat. Additional symptoms can be coughing, headaches, mucus dripping down the back of the throat, loss of appetite and fever (in children). ...Read more

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What is asp?

What is asp?

In acupuncture an: Asp is an acupuncture semi-permanent needle. They are made in germany & come in stainless steel, gold, silver & titanium. They are used for auricular (ear) acupuncture. They are usually referred to as "asp's". ...Read more

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I have cold?

I have cold?

Cold: Tips: sore throat – gargle with warm salt water (1/2 tsp salt in 8 oz of water). Get strep test/culture if very sore. Congestion – saline nose drops or netti pot. For anti-inflammatory effect & mobilizing mucus- homemade chicken noodle soup. Hydrate- lots of water/clear broth/ add honey & a small amt. Of lemon juice to chamomile tea.. Fever/ pain – Acetaminophen / nsaid’s rest! ...Read more

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