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Doctor insights on: Pioglitazone And Metformin Medication

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Is taking metformin with pioglitazone and glimperide tablets safe for long time use?

Is taking metformin with pioglitazone and glimperide tablets safe for long time use?

Yes, unless: Hi. Yes, in general that 3-drug cocktail is safe. Exceptions would be metformin at a certain level of kidney disease, pioglitazone in heart failure, and glimepiride if it's causing hypoglycemia. That 3-drug regimen will likely lose efficacy over time. Keep your diabetes, blood pressure, and lipids tightly controlled. Don't smoke! Good luck! ...Read more

Dr. David Sneid
1,046 Doctors shared insights

Metformin (Definition)

That reduces liver production of glucose- other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk ...Read more


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I am 41 taking:Metoprolol, Pioglitazone, Atrovastatin, Metformin. I had no menses Dec. 2015/Jan 16'; spotting feb. & mar. None Apr. Can med be cause?

I am 41 taking:Metoprolol, Pioglitazone, Atrovastatin, Metformin. I had no menses Dec. 2015/Jan 16'; spotting feb. & mar. None Apr. Can med be cause?

Maybe (not). . .: I like to use www. Drugs. Com to search for medication info. I could not find any mention of irregular menses or amenorrhea (cessation of menses) linked to any of above listed meds. However, there are many reasons for irregular menses, including pregnancy & (early) menopause. If you've never had a fast or irregular heart rate, your doc might consider trading Metoprolol for an ACEI/ARB if BP high ...Read more

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Can the medication metformin lower blood sugar too much?

Can the medication metformin lower blood sugar too much?

Usually no: Metformin is an excellent diabetes medication because it lowers your blood sugar by making you more sensitive to your own insulin, but it will not allow your glucose to go low. Other diabetes medications (glyburide or other sulfonylureas; insulin) can give you hypoglycemia. If your sugars are "low", maybe you don't need the metformin. Has something changed from when you were started (eg wt loss)? ...Read more

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Please describe the medication: metformin?

Please describe the medication: metformin?

Drug for diabetes: That reduces liver production of glucose-

other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk in patients with diabetes. ...Read more

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What happens if she takes metformin 500 mg ER with no medical problems this medication is used for?

Metformin: Metformin is most commonly used for type 2 diabetes. It is also commonly used for gynecology to help treat polycystic ovarian syndrome. ...Read more

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Can someone prescribe metformin for me. My A1C is 7.0? do I need medication at this point or can I continue diet and exercise.

Can someone prescribe metformin for me. My A1C is 7.0? do I need medication at this point or can I continue diet and exercise.

You must schedule an: Appointment to be seen or speak to one of our physicians or call your own prescribing physician. We do not just dispense medicine online: book an appointment. ...Read more

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What natural medications can you use instead of metformin?

What natural medications can you use instead of metformin?

Diet for diabetes: I specialize in this problem. Lets do second opinion consult to see what is going on. ...Read more

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If one feels sick everytime they take metformin should they ook at a different medication?

If one feels sick everytime they take metformin should they ook at a different medication?

Yes: Metformin is a great drug but if it makes you feel sick everytime you take it, then it is not the drug for you. See your doctor to get the regimen reevaluated. There are many other options to choose from. ...Read more

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What other medications are out there for people with type 2 diabetes, other than metformin.

What other medications are out there for people with type 2 diabetes, other than metformin.

Multiple: The medicines used should be dependent on your diabetes, lifestyle, compliance as you and your doctor decide. There is sulfonyl urea, dpp4 inhibitor. Tzd, antiabsorptives, modifiers of renal threshold, and even injectables not insulin. Talk to your doctor and discuss what is best for you. ...Read more

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Do these medications interact? Synthroid 100mcg, metformin (500*3 times a day), emoquette, prenatal

Not likely: I am not aware of any serious drug interactions between these medications. Being on an oral contraceptive however can change the dosage of synthroid (thyroxine) required to keep your thyroid level normal. ...Read more

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I am currently taking metformin and spirolactone. Will I have a bad reaction if I sibutramine along with the medication I am taking? What will occur?

???: Silbutramine was taken off the market in most of the civilized world several years ago because of cardiac concerns. Why are you still receiving it? ...Read more

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43yr old 210ibs, 5', 10", suffering from nonalcoholic fatty liver and metabolic syndrome, and tg340., will metformin help or any other medication?

43yr old 210ibs, 5', 10", suffering from nonalcoholic fatty liver and metabolic syndrome, and tg340., will metformin help or any other medication?

Fatty liver treat: Metabolic syndrome treated with metformin is helpful but u need to follow a low calorie diet exercise and decrease alcohol other treatments are Actos (pioglitazone) it the newly released diet medicines in appropriate settings baristric surgery can be considered. ...Read more

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My blood sugars were normally 85-95 and now they have been 110-113 in the morning I'm not liking this could there be something wrong? Should I go backon my metformin medication. Should I worry liver?

Check w/your doctor: Check w/ your doctor. It sounds like your Insulin resistance has increased or your Insulin secretion ability has decreased. Recent infection, steroids, etc?
Why did you stop your metformin in the first place? Metformin has many positive actions other than keeping glucose down - it can also delay or prevent the development of diabetes. If you're overweight, lose. ...Read more

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I drink coffee in morning can that affect my thyroid medication? I also take metformin, could that affect absorption?

I drink coffee in morning can that affect my thyroid medication? I also take metformin, could that affect absorption?

Wait for an hour: If you drink black coffee, it shouldn't change your levothyroxine absorption. If you put cream or sugar in it, you should try to wait about an hour after taking you medication. You also ideally would want to wait to take your metformin separately as well. ...Read more

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What are some type 2 diabetes so they don't have to take januvia, (sitagliptin) metformin or any pharmacist medication?

What are some type 2 diabetes so they don't have to take januvia, (sitagliptin) metformin or any pharmacist medication?

Diet/Exercise: Please talk to your physician or diabetic educator to develop a treatment plan and let them know you are wanting to look for non-medication treatments. Having said that, the main thing that has caused patients of mine to get off of their diabetic meds is weight loss, exercise, and eating a low-sugar/carb healthy diet. I know that's not easy, but it can make the progression of the disease slow. ...Read more

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Taking metformin (for pcos) gives me significant GI upset; is there something I can do to better tolerate this medication?

ER, take with meals: These side effects are very common. Metformin is best tolerated with taken in the extended release (er) version in one daily dose with a meal, typically with dinner. ...Read more

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When I take my medication metformin I feel sharp pain throughout my intestines when I eat and my kidneys hurt as well what do I do?

When I take my medication metformin I feel sharp pain throughout my intestines when I eat and my kidneys hurt as well what do I do?

Common side effects: Metformin has some common side effects...mostly intestinal, like what you explain. We encourage you take it on a full stomach. There are slow release forms of metformin that might help too. Otherwise you may need to check with your doc wether to lower the dosage a little, often this helps. If none of the above helps, ask your doc to look at an alternative to the Metformin. ...Read more

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I have pcos is the medication given (metformin) a medication I will have to take for the rest of my life? Or how long is one on the meds?

No one knows: The long term safety of metformin for pcos has not been established, nor is it fda approved for pcos, and it is not a cure. However, as long as it works to control your symptoms and you are being followed by a pcp you should continue it. It helps control blood sugars, lowers testosterone production, slows the growth of abnormal hair, restores ovulation, and may help cholesterol levels and bmi. ...Read more

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Is microalbumin among diabetics common. I am diabetic for the past 8 years medication I take is metformin for sugar. And almetor for BP. Miral 42?

Is microalbumin among diabetics common. I am diabetic for the past 8 years medication I take is metformin for sugar. And almetor for BP. Miral 42?

Unfortunately yes: It is common. There is specific therapy for reducing the microalbuminuria and we believe that it reduces the likelihood of having the disease progress or cause sit to progress more slowly. ...Read more

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What is the best alternative medication to sulfonylurea for type 2 diabetics to prevent weight gain in combination with metformin?

DPP4 inhibitor: Newer medications like januvia, onglyza, (saxagliptin) and tradgenta are all effective additions to metformin for the treatment of diabetes, and generally have less weight gain than the older sulfonylurea medications like glucotrol. ...Read more

Dr. Brad Goldenberg
47 Doctors shared insights

Pioglitazone (Definition)

Used together with proper diet and exercise to help control blood sugar in adults ...Read more


Dr. Maureen Mays
49 Doctors shared insights

Actos (Definition)

Actos is a glitazone which is a kind of diabetes-related drug ...Read more