Doctor insights on:
Pioglitazone Allergy In Children
Benefit vs risk..: Like any other medicine in use, consider benefit vs risk--same as driving a car (getting to places faster with risk of accident/breakdown etc.). Currently the biggest concern for people is the risk of bladder cancer on long-term use (40% increase/yr: from 7/10000 to 10/10000 cases). The percentage is big, but absolute is still small. There are alternatives! So, consult doc. Good luck. ...Read more
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
Media frenzy: Actos (pioglitazone) is a good drug for diabetes. All drugs in this class cause fluid retention, which can worsen heart failure in some people. A related drug (avandia) got slammed for increasing coronary heart disease, but this never affected actos (pioglitazone). These drugs may increase bone loss. Now there is a weak inference of bladder cancer, and the media and lawyers are all over this like sharks on fresh meat. ...Read more
Yes: See below, thanks.Get a more detailed answer ›
Minor: The medication has been studied in non-diabetic individuals in early clinical trials for fda approval looking for changes in weight, blood sugar, serum lipid values and blood pressure. There was no evidence of low blood sugars and the other effects were minor. An individual without diabetes should not take pioglitazone. ...Read more
None. But the acai berry is more hype, albeit very rich in anti-oxidants. There are many more potent sources than the acai for anti-oxidants.
But, no risk in taking it with actos (pioglitazone). ...Read more
Actos (pioglitazone): Actos (pioglitazone) should be taken half hour before breakfast and Lisinopril should be taken at the same time daily. ...Read more
You can take in am: Take the pills together in the morning. Then eat a healthy breakfast. The inserts with meds can make it sound more complicated than it needs to be. Just make sure eat regularly to avoid hypoglycemia, and drink plenty of water on the Lisinopril to keep the kidneys working as this is the organ that metabolizes the. Drug. ...Read more
Yes, unless: Hi. Yes, in general that 3-drug cocktail is safe. Exceptions would be metformin at a certain level of kidney disease, pioglitazone in heart failure, and glimepiride if it's causing hypoglycemia. That 3-drug regimen will likely lose efficacy over time. Keep your diabetes, blood pressure, and lipids tightly controlled. Don't smoke! Good luck! ...Read more
Actos (pioglitazone) is a prescription medication used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. Actos (pioglitazone) is not for patients with type 1 "juvenile" diabetes or diabetic ketoacidosis.
Actos (pioglitazone) works on two of the common problems that lead to high blood sugar in type 2 diabetes. ...Read more
Her are some side: Effect of actos:muscle pain -- up to 5.4 percent, tooth problems -- up to 5.3 percent', sore throat -- up to 5.1 percent, swelling or water weight gain, and others not as frequent but could serious.•symptoms of bladder cancer, symptoms of low blood sugar, trouble breathing, swelling, especially in the legs or ankles, rapid increase in weight, liver problems. Good luck. ...Read more
Actos (pioglitazone): Headaches, muscle pains, cold symptoms are common. ...Read more
I'm not a fan: Hi. The TZD era came and went for me. They're not bad drugs in most cases, but they can cause serious weight gain and fluid retention, and we have such better drugs now. I haven't prescribed pioglitazone in years. So, yes, it helps treat diabetes, but other drug choices may have better overall profiles. ...Read more
No: The generic name for Actos is pioglitazone. The medication recently went generic. When any medication goes generic a prescription is still required. ...Read more
Liver enzyme: The cyp2c8 enzyme contributes to the metabolism of many drugs. This enzyme consists of less than 10% of the total cytochrome components in the liver, though has also been found in other organs. Even if inhibited, other pathways are available to metabolize drugs which helps the body avoid toxic build- up of drug metabolites. ...Read more
Not likely: According to my sources, there are no known interactions between Actos (pioglitazone) and any of the most commonly used antidepressants. You should always let your doctor and pharmacist know if you are on other medications they are not providing so they can help you determine if an interaction may occur. ...Read more
There is evidence of an excess number of cases of bladder cancer in patients who have taken the drug Actos (pioglitazone) compared to what might normally be expected in a large group of people.
Epidemiologic research in this regard continues, but it may be prudent for those who have taken the drug for longer than 1 year to be screened for this, especially in patients with other risk factors such as smoking. ...Read more
Not conclusive: There is not confirmation that it causes bladder cancer. The study you are mentioning was done in france where there is a very high percentage of smokers. Smoking can increase the level of bladder cancer. Kaiser is currently doing a large study to see if there is any association. Most of us still use Actos (pioglitazone) with our patients. Diabetes can be a bad disease also. ...Read more