Doctor insights on:
What other antihistamine has antiemetic properties equivalent or superior to phenergan (promethazine)?
Synergistic: Nubain is semi-synthetic opiod analgesic while Phenergan (promethazine) is an antihistamine. The Phenergan (promethazine) is used in the postoperative period to reduce nausea and to potentiate the pain killing effects of the nubain. The hope is to use less Nubain and avoid its possible side effects by using the Phenergan (promethazine) with it. ...Read more
Among other things: Phenergan (promethazine) is a phenothiazine (most of the family are anti-psychotics) which is used primarily for its antihistaminic, antiemetic, & sedative effects. Because it also blocks acetylcholine, it can cause dry mouth, blurred vision, constipation, difficulty urinating. As a phenothiazine it may cause uncontrollable movement disorders (extrapyramidal reaction). Also a photosensitizer. ...Read moreSee 1 more doctor answer
Nausea treatment: Phenergan (promethazine) is a pretty good medication for symptomatic treatment of nausea. Meclizine seems to work better in motion sickness. If you are still symptomatic with those medications, you should be seen and evaluated by your physician to find out what causes it. Many serious health problems can cause nausea and vomitting. ...Read more
Of three anti-emetics (ativan, benadryl, (diphenhydramine) and zofran) used on a pediatric oncology floor, why is ativan used?
It works for some: Each of the three drugs you listed work by targeting a different mechanism to help battle chemotherapy-induced nausea. It is not uncommon for a patient to require a schedule of all three, depending on the chemo being administered and the individual patient. Ativan can help with anxiety, but it is also an anti-emetic. Reglan (metoclopramide) is also commonly given with Benadryl to help fight nausea. ...Read moreSee 2 more doctor answers
No: Nothing always works.Get a more detailed answer ›
NO: However, given the answer above, people will use anything they can get their hands on to abuse, or help with a crash of other drugs. Both, have a high risk of a muscule movement disorder called tardive dyskensia, which can be permanent, and a syndrome called nms, neuroleptic malignant syndrome, which can be fatal... ...Read moreSee 1 more doctor answer
Baclofen VS Anarex: There is no such thing as "safer" medication, only those that work and don't work, based on the patient's individual circumstances and genetics. ...Read more
Compazine (prochlorperazine) does...: Ondansetron (zofran), a powerful anti-nausea drug, is a serotonin 5-ht3 receptor antagonist. It blocks these "receptors" linked to the crtz..The "vomiting center" located in our brains. Compared to compazine, (prochlorperazine) a piperazine phenothiazine linked to other brain receptors (d2), it causes very little sedation. Both are used to decrease nausea and vomiting after surgery. ...Read more
Zofran (ondansetron): Both are similar.Get a more detailed answer ›
Granisetron oral disintegrating 1 mg. tablet for chemo nausea is about equal to how many mgs. of oral disintegrating Zofran (ondansetron) or Zofran (ondansetron) regular pills?
Zofran (ondansetron) dosing: As a single dose before certain chemotherapy regimes, Granisetron can be given as a single 2mg dose, and Zofran (ondansetron) as a single 24mg dose, but only for single day chemotherapy when a high amount of nausea is anticipated. Side effects may occur and you will need to discuss this with your oncologist. ...Read more