Doctor insights on:
Pet Scan Accuracy Cancer Detection
Pet scans most often use a radioactive form of glucose, the energy source for most of the cells in our bodies. The pet scanner can detect and measure how much of the radioactive glucose analog, f-18 fdg, is in a particular organ or region. The areas using more glucose are hyper metabolic and generally more worrisome. Our brains and sometimes hearts prefer glucose as food, making ...Read more
Yes and no: Areas with cancer are usually hypermetabolic in a pet scan due to the increased uptake of the radioactive glucose by cancerous cells. Looking at an FDG pet scan alone, you can grossly see "dark" areas in the brain, heart, kidneys and bladder and these are due to physiologic distribution/excretion of fdg. Not all "dark" is cancer and cancer is often but not always "dark". ...Read moreSee 2 more doctor answers
Glucose: Pet scan relies on the theory that tumors utilize a significant amount of glucose. Many different types of cancer can show up on pet scan but certain types of cancer are much more FDG avid. Low grade tumors usually have much less uptake than high grade tumors. In addition, mucinous neoplasms often do not have much FDG uptake. Small size tumors or micrometastases also may not show up on pet. ...Read moreSee 2 more doctor answers
PET is not 100%: The distribution and intensity of hyper-metabolic activity appearance on a pet/ct scan could be abnormal and may represent malignancy but is not pathognomonic and may also represent inflammation, infection or granulomatous disease. If biopsy is correctly done, results of direct tissue are usually more certain. However, short interval follow-up with pet/ct is often recommended. ...Read moreSee 1 more doctor answer
Uptake on PET: The uptake of 18F-FDG by tissues is a marker for the tissue uptake of glucose, which in turn is closely correlated with certain types of tissue metabolism. Tumors in general are more metabolically active than normal tissues and this difference in uptake is what makes PET scans possible. Tumors that have a higher metabolic rate will have more FDG uptake. Tumors that are less active havel less . ...Read moreSee 1 more doctor answer
Oncology: I've been told by a layperson that a PET scan is able to detect the presence of even a couple of dividing cancer cells. I think not. Right?
Not long ago I had a pet scan done, one lympnode lit up, it was light. I want to know if that still means cancer.?
Possibly: The purpose of a PET scan is to evaluate the extent of a cancerous process and see if before treatment there are several sites to be concerned about. After treatment to see if there is residual disease that may not have responded properly. If a node lights up it may suggest that there is still remaining disease. ...Read more
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