Doctor insights on:
Pet Scan Accuracy Cancer Detection
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Glucose: Pet scan relies on the theory that tumors utilize a significant amount of glucose. Many different types of cancer can show up on pet scan but certain types of cancer are much more FDG avid. Low grade tumors usually have much less uptake than high grade tumors. In addition, mucinous neoplasms often do not have much FDG uptake. Small size tumors or micrometastases also may not show up on pet. ...Read more
Yes and no: Areas with cancer are usually hypermetabolic in a pet scan due to the increased uptake of the radioactive glucose by cancerous cells. Looking at an FDG pet scan alone, you can grossly see "dark" areas in the brain, heart, kidneys and bladder and these are due to physiologic distribution/excretion of fdg. Not all "dark" is cancer and cancer is often but not always "dark". ...Read more
Uptake on PET: The uptake of 18F-FDG by tissues is a marker for the tissue uptake of glucose, which in turn is closely correlated with certain types of tissue metabolism. Tumors in general are more metabolically active than normal tissues and this difference in uptake is what makes PET scans possible. Tumors that have a higher metabolic rate will have more FDG uptake. Tumors that are less active havel less. ...Read more
PET is not 100%: The distribution and intensity of hyper-metabolic activity appearance on a pet/ct scan could be abnormal and may represent malignancy but is not pathognomonic and may also represent inflammation, infection or granulomatous disease. If biopsy is correctly done, results of direct tissue are usually more certain. However, short interval follow-up with pet/ct is often recommended. ...Read more
No: SUV has no bearing on the aggressiveness of the cancer. It is a relative measure of the glucose metabolism. In fact, some very aggressive tumors have no FDG uptake at all. Some benign conditions like infection can have high uptake. The standard uptake value depends on many factors like patient body size and serum glucose level and the normal uptake in the tissue surrounding the target lesion. ...Read more
Not long ago I had a pet scan done, one lympnode lit up, it was light. I want to know if that still means cancer.?
Possibly: The purpose of a PET scan is to evaluate the extent of a cancerous process and see if before treatment there are several sites to be concerned about. After treatment to see if there is residual disease that may not have responded properly. If a node lights up it may suggest that there is still remaining disease. ...Read more
Is it better that the SUV Max on a pet scan is lower than higher? Does this mean the cancer Is less aggressive and less active What is the highest it can be!
What does a cancer free pet scan show? When a pet scan shows that a person is cancer free, does that really mean they're done with cancer? Is it cured? Are there any general statistics for a person who had cancer, but a pet scan later showed that the canc
PET: Pet scans are used for diagnosis, staging, and restaging of certain kinds of cancers such as lung, colorectal, esophageal, and head and neck cancers, and for monitoring response to therapy in breast cancer. Different kinds of cancers behave differently, and there is no guarantee that a given cancer is completely "cured, " even following complete remission. In general, evidence of a complete remission on a pet scan is a very favorable prognostic sign, and indicates that treatment was successful. Followup pet scans are still performed at regular intervals, often for the patient's lifetime, in order to monitor for any possible recurrence that might require new treatment. In general, if follow-up pet scans continue to show no evidence of disease over a period of many years, the likelihood of recurrence is low. ...Read more
My husband had colon cancer, had a colon resection and chemo. He has had 2 pet scans since. Churining?
A PET scan is: The most expensive imaging test. Using it to routine follow up can be justified if it alters care. Usually there is a defined course (# of cycles) and re-staging is done regularly with ct scans. Many insurers engage "pre-approval" screening to prevent over use. There are second and third line treatments for recurrent colon cancer, but ct scans do a good job of picking this up. ...Read more
Tricky: Not all cancers are bright on pet scans and not all bright activity in a pet scan is cancer. Inflammation/infection can also show bright activity. Pet scans are performed in conjugation with ct (pet/ct) and though pet is great for detecting metabolism, its specificity is not as great. Reading a pet requires care/skill. Normal activity is seen in the brain, heart, liver, spleen, kidneys, bladder. ...Read more
Radioactive sugar: A PET scan looks for areas in the body that are using more sugar than other areas. The only way to "see" the sugar is to label it with a short-lived radioactive tag. Areas that are much brighter on the scan than others can indicate areas of tumor, though inflammation and infection can also light up (sometimes to a lesser degree). Details of the clinical scenario should be provided when ordered ...Read more
Follow drs. Protocol: If metabolically active and of significant size tumor of cervix and metastases would likely be recognized on pet scan. Tumor does not arise in one day. Microscopic small lesions detected by pap smear are not likely recognized on pet scan. Treatment is determined by physician taking care of you. ...Read more
After cancer surgery I had 2 clear pet scans. Nw after 5 yrs the pet scan is abnormal. Possible causes?
Not enough info...: It is possible to have an abnormal scan at 5 years but I do not know enough about your history and what was abnormal in this scan. There are many sources of false positive on pet scan but without seeing your images or reports and without your exact history it is difficult to determine what the status is. ...Read more
How many number of pet scans can be used safely if patient insist pet for detecting metastatic lesions after removing primary cancer?
I had a total thyroidectomy due to suspicious nodules. The patho report showed a small 8mm cancer. Will I need to do a pet scan yearly for 5 yrs?
Maybe all done.: You had a total thyroidectomy for a microcarcinoma. Depending upon what the pathology showed, you are done. You can be followed by an endocrinologist who will be able to use a blood test, serum thyroglobulin, to screen for residual/recurrent disease. However, you should understand the nature of your cancer and any other findings in your thyroid outside of the cancer for best follow up care. ...Read more
Oncology: I've been told by a layperson that a PET scan is able to detect the presence of even a couple of dividing cancer cells. I think not. Right?
Mediastinal, bilat hilar & virchow nodes, post cancer 1a. Healtap dr say biopsy/pet scan. My onc dr: if they want u to have that, tell them to do it.
Your doc knows you: Your doctor knows you. No healthtap doctor or other online site knows you the same. There are likely to be many missing details in a short comment like the one you posted. It is imperative to meet with your doctor and ask him/her to explain your illness so you understand it best. If you can't get a satisfactory explanation, it may be useful to get a second opinion. Good luck! ...Read more
Sort of...: The pet scan non-specifically show very metabolically active (consuming lots of energy), and lung cancer and its metastasis fit that category. It is not specific. Benign conditions like sarcoid can also make pet studies glow very brightly as well. Slow growing lung cancer, broncheoalveolar may not be pt avid. ...Read more
PET scan: Pet scans are often used to look for metastatic disease and a clear scan means no obvious disease noted, a good sign but does not always guarantee one is disease free. ...Read more
Need more info: I would say unlikely if pet/ct liver was negative, but I need to know more about your mediacl history and other tests/treatments you may have had. ...Read more
I have a 2 CM nodule and smaller nodules in my lungs. Will be getting a pet scan. How quickly will it spread if it's cancer?
Following cancer surgery I had 2 clear pet scans. Now after 5 yrs the pet scan is abnormal. What can be the reason, what to do?
Abnormal PET....: It is difficult to say without knowing your exact history. What type of cancer was it? Was the pet performed at the same institution and interpreted by the same person? Abnormal pet could mean recurrence but without the report it is difficult to say. There are many causes of false positive on pet. Please look further into this calmly and discuss with your doctor to understand the details. ...Read more
Pet scans most often use a radioactive form of glucose, the energy source for most of the cells in our bodies. The pet scanner can detect and measure how much of the radioactive glucose analog, f-18 fdg, is in a particular organ or region. The areas using more glucose are hyper metabolic and generally more worrisome. Our brains and sometimes hearts prefer glucose as food, making ...Read more
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