Doctor insights on:
Pet Lung Cancer Diagnosis
No such thing: Pet scan identifies increased cellular metabolism. The suv is a measure of how metabolically active a "spot" or "nodule" is. It does not diagnose. Lung cancer (all cancers) is diagnosed by obtaining tissue and examining by pathologist. Any lung nodule must be thoroughly investigated and closely followed by a comprehensive thoracic team. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Several Options: Several tests can help stage lung cancer. A contrast enhanced (injected into a vein) CT is the usual first test. The advantage of a PET/CT (not just a PET) is the ability to look for disease in unexpected places (brain for example) or in areas which appear normal on CT, like small lymph nodes. PET shows areas which are using sugar for energy, as some cancers, including lung, do. ...Read more
Sort of...: The pet scan non-specifically show very metabolically active (consuming lots of energy), and lung cancer and its metastasis fit that category. It is not specific. Benign conditions like sarcoid can also make pet studies glow very brightly as well. Slow growing lung cancer, broncheoalveolar may not be pt avid. ...Read more
Maybe: Most lung cancers will be seen on a pet/ct scan, unless they are very small. But if it's the size of a blueberry or larger, it will be seen. Pet scans show bright spots where cells are using a lot of sugar (see picture). This can be from a cancer, an infection, or inflammation. So a negative pet scan means you probably don't have lung cancer. If you do, it's tiny! I hope you feel better! ...Read more
Does a PET scan have a much better chance of picking up a central lung cancer if it was missed at LDCT?
LDCT is a : Noncontrast lung nodule screening study, and it is possible that small central lesions may not be visualized due to proximity to normal blood vessels or other structures. PET is extremely sensitive, but if a diagnostic contrast enhanced CT scan with thinner collimation and higher resolution is negative, probably unnecessary. ...Read more
Can pet scan always diagnose /confirm presence of lung cancer or can only give indication and later biopsy is vital to confirm cancer if a nodule seen?
Bx definitive: A positron emission tomography (pet) scan is an imaging test that uses a radioactive substance called a tracer to look for disease in the body. It is often used to determine the treatment of cancer, if it is spreading, or improving, etc. Used in combination with tests such as ct or mri, it can provide a very high index of suspicion for cancer, but a bx is always definitive and used for tx. ...Read more
What test is best to rule out lung cancer or lukemia? MRI with contrast or pet scan? Been having heavyness weak pulse for 6 months
Tests: The best test to screen for lung cancer, in my opinion, is a chest ct scan as a conventional chest xray can miss it. A simple blood test, cbc and differential, is adequate to screen for leukemia. These are screening tests but a tissue diagnosis is required in most cases for a definitive diagnosis. Your pulse description is nonspecific. An MD can check your bp and pulse to look for abnormalities ...Read more
Fatigue for 3 yrs some muscle loss. PET showed 8mm cervical nodes suv2.2. noted unremarkable. Should I still worry about potential for lung cancer?
Paratracheal lymph node grown from 0.6cmx1cm to 0.8cmx1.35cm over 2 years. No SUV uptake on PET. Have fatigue, could this be lung cancer? Lungs clear.
My mom has stage 4 lung cancer. The pet scan showed 3 lesions by the spine. Does this mean the cancer has spread to her bones?
By the spine may b: Different from on or in the spine. Ask her Docs for specifics. ...Read more
How often do you need to use PET scan or bronchoscope to locate lung cancer because it does not show on CT scan but symptoms tell you to keep looking?
Clinical judgement: This pathologist is underwhelmed with the health or public benefits of intensive screening for tiny lung cancers. I'd hope that if the person is symptomatic, some other investigations are undertaken and the actual cause gets found. ...Read more
Fatigue 2 years. CT shows paratracheal node increasing over 2 years, 0.5x0.9cm to 0.7x1.1cm to 0.9x1.35cm. No uptake at PET. Worried about lung cancer?
Could my water retention for last two years be due to an undetected small cell lung cancer. Sodium has also been low over this time but pet/ct clear.
It is extremely: Unlikely that you would survive for two years with undetected and untreated SCLC. Therefore, it is unlikely that water retention would be caused by undetected SCLC. Low sodium and "water retention" suggests to me that you are over hydrated. Restrict your total fluid intake to <1.2 Liter/24 hours for three weeks and see if your retention resolves and your sodium improves. ...Read more
Life expectancy for lung cancer gone to brain. Pet scan shows no other cancer now, only 1 tumor on brain. Surgery and whole brsin radiation will be?
"oligometastatic": Patients with a single brain tumor as the only site of metastatic disease are called "oligometastatic." the chance of cure, though small, is real. Every cancer specialist has a few such patients. I would strongly recommend aggressive treatment, including either radiosurgery (cyberknife, gammaknife, etc.) to the brain or surgical resection, and again stereotactic or chemoradiation to the lung. ...Read more
In past 3years I have had 3 CT scans and 1 pet/ct scan all negative. Do I need more scans to rule out lung cancer? Still, have fatigue and muscle loss
You don't have it: Whether scans cut a risk of one's actually dying of lung cancer is a question I will leave to policy-makers. But your fatigue and muscle loss are not due to lung cancer. I'm glad your health conscious; I assume you've stopped smoking; and my hope for you is that you'll search for some other explanation AND continue an athletic, fitness-focused lifestyle to richly enjoy these years of your life. ...Read more
Does a negative pet/ct exclude lung cancer as a cause of my non-specific symptoms including fatigue, muscle loss and night sweats. Thank you.
20 months fatigue. LDCT negative in Aug 16. Ongoing sympts PET/CT neg in Nov16. Still fatigued & muscle loss, scan further for lung cancer? Thanks
Need more informatio: We need more information to advise you. We need to know your clinical evaluation, laboratory findings, etc ...Read more
Fatigue for 2 years with some muscle loss. Pet/ct scan was negative. What is chance of it missing lung cancer (exsmoker sorry, clean 2 years). Thanks?
Not zero: But very small. No test is perfect. There are a number of reasons for missed diagnosis of lung cancer. However, a PET CT is the best way to identify lung cancers. Not all nodules seen on CT are positive on PET but this is rare. If no nodules are seen on PET or CT, then the likelihood is less than 2-3/10,000. If you are worried, you can have a follow up low dose screening CT. PET is not needed. ...Read more
Does negative PET/CT rule out lung cancer for ongoing fatigue of 2 years & low sodium. Chest CT clear Feb 2016. Also, lost muscle, now concerned. Thanks?
Gen anaesthetic in Aug14 for knee op. Woke up with lung sharp pain on breathing lasted 2 weeks. Still suffering fatigue. Clear pet Oct16. Lung cancer?
Atelectasis: Gen Anesthesia w/ breathing tube and controlled ventilation can cause the normal lung to be under inflated during surgery. Once you are awake and breathing spontaneously the lungs re inflate to normal capacity. This can cause some pain esp if you are a smoker, Asthmatic, Obese, Obstructive sleep apnea, not physically fit. If pain and fatigue cont. See your PCP. ...Read more
3 years of non-specific symptoms then diagnosis of small cell lung cancer. What is likelihood of 3 year of symptoms relating to sclc? Thank you.
Zero: I'm sorry about your cancer. Small-cell grows very fast, usually from nothing, and folks typically remember symptoms beginning days or a few weeks before diagnosis. The cough, weight loss, and malaise that may herald this illness are also those of emphysema from the smoking that usually causes small-cell. I hope you get effective treatment and with today's Rx perhaps great luck. ...Read more
After diagnosis of lung cancer is made the next step is to accurately stage the cancer so that appropriate therapy can be discussed.
25% of lung cancers are Stage I or II at diagnosis and are treated with surgery. 75% of lung cancers are Stage III or IV. Selected Stage III cancers may be treated for cure with multi-modality treatment. Palliative treatment is used for most Stage III & all Stage IV ...Read more
Would you have symptoms of small cell lung cancer for 18 months prior to diagnosis, or does small cell grow too rapidly for this to happen?
Depends on the grade: After a biopsy, when small cell carcinoma is diagnosed, it is often given a "grade" by the pathologist (e.g., low-grade or high-grade) based on the appearance under a microscope. There are small cell cancers that can grow slowly, & only be discovered on screening CT scans (not causing any symptoms). Others cause symptoms & spread quickly (high-grade). Not all small cell cancers behave alike. ...Read more
I am just curious about what are the first symptoms of lung cancer, how long does it take a smoker to get it and what is the average age of diagnosis?
Often asymptomatic.: This is often asymptomatic with about 5-15% detected from symptoms. Pesistent cough is the usual presenting sign, with hemoptysis, wheeze, dyspnea or difficulty breathing, depending on its site. Hoarseness, and respiratory failure can mean spread beyond the lungs. This occurs most at 55-65 years and since smoking is the most common cause, it likely takes from its start so don't start smoking. ...Read more
Adenocarcinoma-non-small-cell lung cancer. How many people are doing ok after 1 year from diagnosis?
Stage and biology: It depends on the stage, the biology/genetic profiles, the treatment you received, age, overall condition etc. The earlier your stage is the higher your overall survival percentage is- off course providing that you receive the appropriate treatment. Discuss in detail with your oncologist. ...Read more
Can a diagnosis of lung cancer which already has spread to the liver, be mistaken for something else?
Infection: Clinical presentation of the patient and a confirmatory biopsy would be necessary if there was a question as to the diagnosis. ...Read more
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more
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