Doctor insights on:
Pet Esophageal Cancer Initial Staging
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?
Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
GB cancer is: Uncommon, so few studies done prospectively. Looking at results in people treated empirically, perhaps one person in 10 will respond. That needs to be balanced against side effects that tend to occur in most. Frank discussion about symptom rrelief focus rather than "shrink tumor" at all cost. ...Read moreSee 1 more doctor answer
Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read moreSee 1 more doctor answer
Yes/No: For early detection of Cancer, there are well defined screening guidelines which your primary care physician can share with you and guide you. For Colon cancer CT scan is not a good screening test. Instead Colonoscopy is the best test,but it is to be done> 40 years of age unless you have any symptoms like rectal bleeding or abdominal pain. Best thing you can do is to have an annual Physical exam. ...Read moreSee 1 more doctor answer
Prostate cancer: This is an advanced stage of prostate cancer; the good news is there are many new drugs and treatments for men in this stage that have been shown to extend life; in this stage survival is extremely variable from months to years isn't impossible. ...Read moreSee 1 more doctor answer
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Not good: Stage 3b non-small-cell-lung cancer is a very heterogeneous group of patients and as such there is no unanimous hard data on survival, unlike the earlier stages. Some may benefit from chemo- and radiation therapy to shrink the tumor and be resected. My advice is to go to the most renowned lung cancer specialist that is available to you and hope for the best. ...Read moreSee 1 more doctor answer
How sensitive is pet scan in detecting metastatic clear cell renal cancer, irrespective of screening guidelines (uiss/nccn) , side effects, cost?
TNM breast cancer: Tnm is one of the staging system commonly used for cancer. It stands for t-tumor ( the size of the tumor- the bigger is the tumor the higher is the stage) ; n- nodal status ( involvement to the lymph glands) - and m- presence of metastatic disease to the distant organ. See more here: http://cancer.Gov/cancertopics/wyntk/breast/page7. ...Read moreSee 1 more doctor answer
Tumor size & spread.: Stage i: the cancer is not touching the major blood vessels near the pancreas. Stage ii: the cancer extends beyond the pancreas, or the cancer has spread to a nearby lymph node. Stage iii: the cancer has wrapped around the major blood vessels near the pancreas. Stage iv: the cancer has spread to other organs. Surgery is usually not recommended for stage iii or IV tumors, but there are exceptions. ...Read moreSee 1 more doctor answer
Is tamoxifen essential in invasive ductal carcinoma (HR+/ER+)?
Does additional chemotherapy is neccesary in stage 1 cancer?
Yes, depends: Yes, anti-estrogen therapy is essential for ER+/PR+ invasive ductal carcinoma. While tamoxifen is used in premenopausal women, femara (letrozole) or arimidex used in postmenopausal women. Some stage I breast cancers (ER+/PR+) do not require further chemotherapy, others do. The need for additional chemotherapy can be assessed by tumor size, recurrence score from a special molecular testing, and etc. ...Read more
Many diseases have specific treatments based on their severity. A disease can have certain criteria to determine their severity and applying this criteria to determine how advanced the disease state is called staging. Most commonly this is applied to cancer, and be determining how far the cancer has spread locally and/or to distant sites a stage of cancer can be ...Read more
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