Doctor insights on:
Pet Cervical Cancer Initial Staging Or Restaging
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?
Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Prostate cancer: This is an advanced stage of prostate cancer; the good news is there are many new drugs and treatments for men in this stage that have been shown to extend life; in this stage survival is extremely variable from months to years isn't impossible. ...Read moreSee 1 more doctor answer
Yes/No: For early detection of Cancer, there are well defined screening guidelines which your primary care physician can share with you and guide you. For Colon cancer CT scan is not a good screening test. Instead Colonoscopy is the best test,but it is to be done> 40 years of age unless you have any symptoms like rectal bleeding or abdominal pain. Best thing you can do is to have an annual Physical exam. ...Read moreSee 1 more doctor answer
Depends on cancer: Each cancer type has an optimum way to image it, especially with techniques that image physiology, like pet and bone scan, as opposed to techniques that image anatomy, like ct and mri. Pet is best for cancers that use a lot of glucose as an energy source, like lung cancer. Bone scans are best for cancers that disrupt bone, like prostate cancer. ...Read moreSee 2 more doctor answers
Several Options: Several tests can help stage lung cancer. A contrast enhanced (injected into a vein) CT is the usual first test. The advantage of a PET/CT (not just a PET) is the ability to look for disease in unexpected places (brain for example) or in areas which appear normal on CT, like small lymph nodes. PET shows areas which are using sugar for energy, as some cancers, including lung, do. ...Read moreSee 1 more doctor answer
Can hodgkin lymphoma transform to NHL? After 4 cycle of ABVD, PET showed an area with SUV 14. Initial diagnosis was HL IIb, bulky.
Yes it can: This change has been reported, so it is entirely possible. But only a biopsy of the new area or the growing lymph node can determine what is going on. Your oncologist should be able to help address this matter for you. Or you can seek a second opinion from another medical oncologist, if you are not totally satisfied with your current oncologist. ...Read more
How sensitive is pet scan in detecting metastatic clear cell renal cancer, irrespective of screening guidelines (uiss/nccn) , side effects, cost?
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
If lymph nodes clear in primary invasive casinoma of the breast stage 1, can bone metastasis occur ?
How long is process of evaluating mass after mammogram including biopsy or lumpectomy? Then how long till radiation? Probable dcis or stage 1 ductal.
3-5 weeks: Biopsy should be done soon after a suspicious lump is detected either by physical examination or mammogram. If it is cancer or dcis, a lumpectomy should follow anywhere from a few days to a few weeks later. The start of radiation depends on healing after lumpectomy, but radiation generally starts about 4 weeks later. Radiation generally takes 6-7 weeks to complete. ...Read moreSee 1 more doctor answer
Is tamoxifen essential in invasive ductal carcinoma (HR+/ER+)?
Does additional chemotherapy is neccesary in stage 1 cancer?
Yes, depends: Yes, anti-estrogen therapy is essential for ER+/PR+ invasive ductal carcinoma. While tamoxifen is used in premenopausal women, femara (letrozole) or arimidex used in postmenopausal women. Some stage I breast cancers (ER+/PR+) do not require further chemotherapy, others do. The need for additional chemotherapy can be assessed by tumor size, recurrence score from a special molecular testing, and etc. ...Read more
Not good: Stage 3b non-small-cell-lung cancer is a very heterogeneous group of patients and as such there is no unanimous hard data on survival, unlike the earlier stages. Some may benefit from chemo- and radiation therapy to shrink the tumor and be resected. My advice is to go to the most renowned lung cancer specialist that is available to you and hope for the best. ...Read moreSee 1 more doctor answer
Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read moreSee 1 more doctor answer
Stage iii-b colon cancer removed surgically. Suspected liver lesion resected and analyzed with not malignancy. Is kras analysis needed for recurrence?
Possibly: For initial treatment after surgery, you shouldn't need to get kras testing. However, if this is metastatic or recurrent colon cancer, then it may help to determine if egfr based therapies like Cetuximab can help (they only work for kras "wild type"). Remember that if you do recur (god forbid), management may be different at that future time! not something to worry about with your current story. ...Read moreSee 1 more doctor answer
Many diseases have specific treatments based on their severity. A disease can have certain criteria to determine their severity and applying this criteria to determine how advanced the disease state is called staging. Most commonly this is applied to cancer, and be determining how far the cancer has spread locally and/or to distant sites a stage of cancer can be ...Read more
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