Doctor insights on:
Pet Breast Cancer Recurrence
This depends on if your are looking for local recurrence in the breast (ultrasound can help) or distant recurrence (in other organs outside the breast)-pet is better.
They are both great tests. If you have concerns, I recommend contacting your oncology team and consider getting a second opinion. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Support: Have you discussed your prognosis with your doctor? Good places to start would be other patients that have been through similar situations. Seek out support groups! Get involved in a charity! Be active! ...Read more
Tumor factors - based on TNM staging, receptor status, grade etc
treatment factors - optimal therapy vs. Not
patient factors - genetic predisposition - this is rarely the issue
time factor - longer the time lapse since initial therapy, lesser the odds. ...Read more
Variable.: Breast cancer may recur either in the breast ("local recurrence") or elsewhere in the body (distant metastasis). The risk of metastasis varies from very low to high, and is correlated with the stage of the cancer; the stage is associated with the size of the cancer and lymph node involvement. Local recurrence following lumpectomy and radiation therapy is less than 5%. ...Read more
NO: There is never an always or never a never in medicine. All patients are individuals ...Read more
The chance of having breast cancer recur is about the same for every year that you are alive. The chance of having cancer come back in the tenth year after treatment is not significantly lower than having it come back in the fifth year after treatment.
For more info:
http://www. Ccij-online. Org/article. Asp? Issn=2278-0513;year=2012;volume=1;issue=4;spage=201;epage=205;aulast=saha. ...Read more
10-15% Hereditary: We believe that only 10-15% of breast cancers are hereditary, with the rest being environmental in origin. People w/the hereditary form of breast cancer tend to get diagnosed earlier in life and may get cancer in both breasts. When treated by lumpectomy or (single) mastectomy, it is not uncommon to develop a second, unrelated breast cancer; therefore, many opt for double mastectomies. ...Read more
YES for ER positive: Oopherectomy has been proven to reduce recurrence in estrogen-receptor positive pre-menopausal women. Prior to tamoxifen, it was a commonly used treatment for metastatic disease and is now known to reduce recurrence in high-risk premenopausal hormone-receptor positive breast cancer, even without the use of other endocrine therapies. ...Read more
Is it possible to have a recurrence from triple negative breast cancer even after being in remission for 10 years?
Is arimidex (anastrozole) when given as prevention of recurrence of breast cancer only used with estrogen receptive cancer?
Yes*: Arimidex (anastrozole) belongs to a category of drugs called aromatase inhibitors. These are effective chemotherapeutic agents for people with either estrogen-sensitive or *progesterone-sensitive breast cancers. This is only effective after menopause; premenopausal women may use tamoxifen for a similar response rate. ...Read more
The bone dr gave me strontium ranelate for my osteoporosis t-3.5. Is it true it increases risk for breast cancer recurrence?
There is not a single paper published using the words strontium renalate and cancer in its title:
http://www. Ncbi. Nlm. Nih. Gov/pubmed? Term= (strontium%20ranelate%5btitle%5d)%20and%20cancer%5btitle%5d
i think you can be reassured.
There is a radioactive strontium that is sometime used for bone metastasis treatment, and that, or course, would be more concerning. ...Read more
Lump in surgery scar: When surgery is performed, many hair follicles in the area are disrupted in the area and new cysts can form. Cysts are not a problem. However, in the area of previous breast cancer, we would be concerned about a recurrence, so any new lesions must be seen by a dermatologist or the breast surgeon. ...Read more
My mom has 3rd breast cancer recurrence but is brca1/2 negative. Am I high risk for breast cancer?
Yes you are: Breast cancer does have some hereditary tendency. So sisters and daughters of a breat cancer patients have a small increase in their risk for developing breast cancer. Yet >90% of the time there is no relationship to such an occurrence. So you need to be vigilant but not worry much about it. Just learn about breast self examination and do annual mammograms beginning at age 40 yr. ...Read more
My mom had been diagonsed with breast cancer chest wall recurrence and surgery had been done and lump had been removed.
I had a hysterectomy at 26 after her 2 positive breast cancer recurrence during pregnancy. I am overweight and need tips to best lose weight please! ?
Walk and weights:
The way to lose weight is to "burn" more calories than you eat.
1st- muscle uses more calories at rest than fat, so increasing muscle in the body increases the calories burned all day, every day. Train with situps, pushups, wall sits, and using elastic bands (huge stretchy bands).
2nd - walk! Build up to 2-3 miles a day.
3rd-keep track of calories and workouts. Try "my fitness pal" (free app). ...Read more
Bright: Pet scans take advantage of the thought that most caners are more metabolically active than the normal tissues around them. This makes the cancers show up as "hot" or "bright" on pet imaging. There are other areas that are "bright" normally as well, like brain and to some extent liver. However, when using pet for breast cancer staging one is looking to see if there are unexpected bright areas. ...Read more
I have Stage4 Breast Cancer. PET showed Multiple subcentimeter lesions and focal fatty marrow within the left sacral ala. Areas for concern?
Yes: May need to sample the area (biopsy) to make sure is not a metastatic lesion (s) ...Read more
Image?: DO YOU HAVE A COPY OF THE IMAGE TO SHOW ONLINE? DID YOU MEAN YOU WANT TO KNOW WHO TO SEE FOR A SECOND OPINION? IF IT IS THE LATTER, YOU NEED TO SEE AN ONCOLOGIST. ...Read more
PET - CT: Pet-ct scans are a means of combining the x-ray of a ct scan with the functional study of a pet scan. The pet scan can see over-active cells that are actively using glucose. The over-active cells may represent cancer cells and is a means of telling if cancer cells are spreading or growing somewhere in the body. The ct scan may see a growth & the pet scan can see if the growth has overactive cells. ...Read more
What could be the causes of increased uptake by a nonenlarged subcarinal node on pet scan in a patient with breast cancer?
Dx breast cancer at 39, thyroid cancer at 40. Is a PET scan needed to rule out mets and am I at a risk for other cancers?
Genetic testing: You definitely need genetic counseling and testing. A complete family history will help direct this as well. There is no role for screening to look for metastatic disease if you are not known to have it. ...Read more
Pet scan in jan 2013 showed 4 cancerous nodules in lungs from breast cancer. New pet scan july 2013 - lung spots no longer metabolically active; does this mean they are no longer cancerous?
Favorable Response: Pet provides the benefit of early identification of ineffective chemotherapy, particularly metastatic breast cancer, as various alternative treatment options are available & allows patients to be spared the toxicities of ineffective treatments. Complete metabolic response is a great prognostic indicator with significantly increased overall survival compared to patients showing no response. ...Read more
Oct 2012-pet scan done with 2 areas of concern after breast cancer dx....Had biopsy and bone scan that were both neg...All cancer treatment done and #2 pet showed same areas-no change. Why bone scan?
D/w your MD: The best person to answer your question is your doctor. Have a discussion with your doctor and see what the reason is. Most likely is the same reason your doctor did the bone scan last time- to ensure that this is also unchanged on the bone scan. Unlike the bone scan, the pet scan was not done dedicated only to check the bone. What is your cancer marker, alkaline phosphatase level? D/w your md. ...Read more
An MRI in nov 2012 showed a radiological cyst on l. Femur; pain since may 2012. I have stage 111c breast cancer. Should I get a pet /ct?
What is the best treatment for s tage 2a breast cancer in a 63 yo male. No nodes were positive and pet CT scan was negative. Er positive.?
Tamoxifen: After a mastectomy, use of tamoxifen in an er+ tumor has the best historical experience for this rare condition in men. The decision to use chemotherapy may depend on comparable metrics used for breast cancer in women such as size of tumor, grade, presence of markers (her2neu, high ki- 67). Though no data in men, oncotype DX theoretically can help with treatment decision about need for chemo. ...Read more
Do I need a pet scan after surviving breast cancer? I had breast cancer (stage 1) and treatment was successful. I just had a mammogram and there was no cancer. Treatments were chemotherapy and radiation.
You and your oncolog:
You and your oncologist need to discuss this. Given the low stage, and assuming successful completion of treatment, pet/ct might not be indicated at this time. It does depend on the specifics of your case.
Pet/ct is useful in evaluating for distal metastatic disease. It does not replace mammography, ultrasound or breast MRI for local recurrence surveillance ...Read more
It can, indirectly.: If you just received the news of having breast cancer, the anxiety and stress associated with that can make your heart skip a beat and make you faint. Also, pain medication and chemotherapy regimens that patients with breast cancer sometimes receive can make one weak and dizzy. ...Read more
One In A Million: The incidence of breast cancer in teenagers is actually less than 1in a million. Benign breast lumps such as fibroadenomas are not uncommon, however. Regardless of age, any new lump warrants medical evaluation. ...Read more
Variable: First and foremost, not all breast cancers spread: many are confined to the breast without any ability to travel to other organs. For those that 'spread', the growth rates vary between months to decades before they become detectable. Furthermore, chemotherapy may eradicate these cells that have spread, and they may never become evident. ...Read more
I wish we knew!: We really don't know what causes breast cancer. We do know that women with a long exposure to estrogen are at a higher risk. If you started your period early, or never got pregnant, you have more estrogen exposure. But these are things you can't really change. However, alcohol intake is associated with breast cancer, so decrease how much you drink. And lower your body fat. And avoid bpa plastics. ...Read more
Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more
Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more
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