Doctor insights on:
Person Thalassemia Marry Safely
Sure: Thalassemia is generally a recessive trait, though through the vagaries of genetics your children could still be affected, but much less likely so. Thalassemia usually doesn't cause significant harm, but does need to be identified and counseling done regarding future labs. So if you love the guy, probably going to be worth it! ...Read moreSee 1 more doctor answer
I'm not aware...: Of a thalassemia specific diet. A few thoughts though. A balanced diet is advised for anyone. Thalassemia pts can have ineffective erythropoiesis, and more rapid red cell turnover. Thus a folate (folic acid) supplement could be warranted. Also, pts often have more robust fe absorption, so monitoring may be warranted. You should be followed by a hematologist or a primary provider comfortable w/ thalassemia. ...Read more
Yes: It's a horrible disease but the newer remedies are helping these folks live longer and better. ...Read more
Yes: Marriage is no problem. Getting pregnant, however, may not be recommended if they have moderate or severe thalassemia. If they have only "trait", they will be fine if their children only inherit "no trait" or "trait from either mom or dad". If a child inherits "trait" from both mom and dad, the child might have a problem. A geneticist and hematologist can give more details for individual cases. ...Read moreSee 1 more doctor answer
Hgb A2 and Hgb F: Thalassemia is a genetic disease and depending of the genetic type it will be major or minor. Anemia is severe plus others serious symptoms, splenomegaly, growth retardation, abnormal bone marrow.The level of serum bilirubin, iron and ferritin are elevated. Bone marrow study reveals market erythroid hyperplasia. The minor type has a benign course. Complete blood count is an important test also. ...Read more
Yes!: Sickle cell and beta thalassemia both affect the same part of hemoglobin. If you inherit a sickle gene from one parent and a thalassemia gene from the other, you have sickle/b-thalassemia. The severity depends on whether the thal gene works a little (b+) or not at all (b0). Sickle cell and Alpha thalassemia are inherited independently; you can inherit both from the same parent or one from each. ...Read more
Yes: The mutations causing sickle cell disease and beta thalassemias both occur in the beta hemoglobin gene. There are many people who have one copy of beta hemoglobin with the sickle cell mutation, and the other copy carries a beta-thalassemia mutation. Depending on the combination, symptoms can vary. For a nice summary, see: http://www.Cdc.Gov/ncbddd/sicklecell/facts.Html. ...Read moreSee 1 more doctor answer
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