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Doctor insights on: Person Thalassemia Marry Safely

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Can a person with alpha thalassemia marry someone with beta thalassemia safely?

Can a person with alpha thalassemia marry someone with beta thalassemia safely?

Yes: Marriage is no problem. Getting pregnant, however, may not be recommended if they have moderate or severe thalassemia. If they have only "trait", they will be fine if their children only inherit "no trait" or "trait from either mom or dad". If a child inherits "trait" from both mom and dad, the child might have a problem. A geneticist and hematologist can give more details for individual cases. ...Read more

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Dr. Michael Engel
272 doctors shared insights

Thalassemia (Definition)

An inherited condition ...Read more


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Can a person wtih alpha thalassemia trait donate blood?

Can a person wtih alpha thalassemia trait donate blood?

Maybe: A person with Alpha thalassemia trait may be not anemic or mildly anemic. If he is not anemic, he can be a blood donor. However, since he has a more difficult time making hemoglobin (to make new red blood cells), he may not wish to be a blood donor. ...Read more

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Can a normal & healthy person may marry with e beta thalassemia , safely?????

Can a normal & healthy person may marry with e beta thalassemia , safely?????

Yes: If you do not carry the gene in any way, any children will be carriers. HbgE/beta thalassemia is a disease that can be mild or severe. The best way to ease your mind is to seek genetic counseling. All the best. ...Read more

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Can an alpha thalassemia carrier marry a beta thalassemia carrier?

Can an alpha thalassemia carrier marry a beta thalassemia carrier?

Of course you can: A person can marry anyone they like. From a thalassemia perspective, and assuming your Alpha thal trait is in cis, your child has a 50/50 chance of being Alpha thal trait vs. Normal and a 50/50 chance of being beta thal trait vs. Normal. Given there is consideration of inheriting two distinct trait states, it would be prudent to sit with a genetic counselor to understand the implications clearly. ...Read more

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Can sickle thalassemia patients get married ?

Can sickle thalassemia patients get married ?

Yes: You need to be aware of the likely consequences if you marry someone with similar genetic mutations. It's a horrible thing to live with sickle cell disease or thal major. Get good genetic guidance if you are are considering starting a family together. ...Read more

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Ivf ethical for people with sickle cell trait?

Ivf ethical for people with sickle cell trait?

Yes: But you should also have your partner tested. If he also has the sickle cell trait, then you can actually have the option to do genetic testing to pick embryos that are not effected with sickle cell disease. ...Read more

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It happens that a man with hemoglobin e-trait father a thalassemic child?

It happens that a man with hemoglobin e-trait father a thalassemic child?

It's possible. : Thalassemia is a condition characterized by reduced expression of either Alpha or beta globins, which together make up hemoglobin. There are people who have Alpha deficiencies that are clinically silent (so called silent carrier). Having a child with person with alpha-thal trait, for example, is one way to have a clinically significant alpha-thal. There are other possibilities as well. ...Read more

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Are blood transfusions after delivery be safe for someone with alpha thalassemia trait?

Are blood transfusions after delivery be safe for someone with alpha thalassemia trait?

Safe if necessary: Blood transfusions are given only when necessary especially in the younger population or blood disorders. Transfusions are necessary for major bleeding resulting in shock, low blood pressures, or continued blood loss. All transfusions are screened and safe but there is always a 1-3% risk of a clerical error. Pts. With blood disorders face increased risk of blood transfusion reactions. ...Read more

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How can one inherit alpha thalassemia?

4 alpha genes...: It is a bit complicated given that there are 4 Alpha chain genes and Alpha thalassemia can involve mutations in one, two (in two different ways) or three genes (mutations in four genes is usually not compatible with life). For excellent website, see: http://www.Stjude.Org/stjude/v/index.Jsp?Vgnextoid=d966885309c6f110vgnvcm1000001e0215acrcrd. ...Read more

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Can a person with beta thalassemia trait be a blood donor?

Can a person with beta thalassemia trait be a blood donor?

Yes, but unlikely: A person with beta thalassemia trait may be not anemic or mildly anemic. If he is not anemic, he can be a blood donor. However, since he has a more difficult time making hemoglobin (to make new red blood cells), he may not wish to be a blood donor. ...Read more

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Is it safe to marry a thalassemia minor patient?

Yes, but: Yes, but you should be tested to know your status if you plan to have children. The thalassemia minor won't hurt you at all. If your partner has thalassemia minor (i.e. Thalassemia trait), i would bet they are fine and have no issues. If you also have thalassemia trait, there is a chance you could have a baby with thalassemia (disease). You should see a genetic counselor. ...Read more

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If a man with sicklecell trait will all his children carry the trait?

If a man with sicklecell trait will all his children carry the trait?

No choice: Statistically ,half the offspring would be expected to get the trait and half not.However, every time you conceive, you flip a coin and get what you get.Every kid might get trait, every kid might be normal, or some of either. ...Read more

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Can a person who has sickle cell trait and "O" Positive blood, donate blood?

Can a person who has sickle cell trait and "O" Positive blood, donate blood?

Sickle cell trait: If you have the trait you can donate blood, but if you have the disease you are not eligible ...Read more

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Interested to know how does a person inherit trisomy 13?

Interested to know how does a person inherit trisomy 13?

They don't: Trisomy 13 is a spontaneous new event that occurs when 2 #13 chromosomes in either the egg (sperm) join with the one from the opposing side. The other 22 chromosomes pass only one of each. The fetus ends up with 47 chromosomes, not the normal 46. It is not passed on the genes like eye color or other features. It is an accident of nature. ...Read more

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How does a widowed father deal with a young lady who wants to marry him?

How does a widowed father deal with a young lady who wants to marry him?

Depends: Do you have feelings for her? You must have at least made some entry level gestures. Does she love you or does she just want your cash, or security, or someone to help share childcare issues? Would she still want you if she had to sign a pre-nuptial agreement? Is there a significant age difference? So many questions. There are counselors for this as well. ...Read more

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What to do about alpha thalassemia trait (minor) with asthama?

What to do about alpha thalassemia trait (minor) with asthama?

Nothing: Alpha thal minor is uttery trivial. Manage your asthma and if you choose to marry, be aware of your alpha-thal and the risk that marrying someone else with the same condition puts your children at risk. ...Read more

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If both parents have thalassemia trait, what will happen with their offspring?

25-50-25: Generally, the hemoglobinopathies are inherited in an autosomal recessive fashion, which means you must have an abnormal copy of the gene from each of your parents. If each parent has one abnormal copy of the same gene, then each child has a 25% chance of being normal, a 50% chance of having one copy of the abnormal gene (trait), and a 25% chance of having two abnormal copies (thalassemia.). ...Read more