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Doctor insights on: Periventricular Leukomalacia

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Dr. Dariush Saghafi
37 doctors shared insights

Periventricular Leukomalacia (Overview)

Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder.


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I am a basket case. My son has periventricular leukomalacia. Can you tell me something about it?

I am a basket case. My son has periventricular leukomalacia. Can you tell me something about it?

Discriptive term: Pvl is used to describe changes in the appearance of the brain substance that is adjacent to the ventricles of the brain (spinal fluid containing sacs in the middle). This occurs when blood flow or oxygen delivery to those sites was interupted and injury occured. Outcome is variable & movement disorders& motor delay are common. Therapy will often improve outcome. Developmental followup is a must. ...Read more

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Dr. Dariush Saghafi
37 doctors shared insights

Periventricular Leukomalacia (Overview)

Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder.


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What are the symptoms of periventricular leukomalacia?

What are the symptoms of periventricular leukomalacia?

Symptoms: Periventricular leukomalacia is a condition that mostly affects preterm infants. The hallmark symptom present in these children is a bilateral spasticity of the lower limbs. ...Read more

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What are the tests for periventricular leukomalacia?

What are the tests for periventricular leukomalacia?

Visible on US or CT: An ultrasound done through the soft spot will often detect pvl. Ct or MRI might also be helpful but the cranial ultrasound is easy to do & requires little preparation or stress on the patient so it is the more common study for this dx. ...Read more

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Can a combination of omega fatty acids 3, 6, 9 along with spirulina be helpful in treating "periventricular leukomalacia" for a kid of 11 years?

Can a combination of omega fatty acids 3, 6, 9 along with spirulina be helpful in treating "periventricular leukomalacia" for a kid of 11 years?

Unlikely to matter: Pvl is similar to having the corn crop die when it doesn't get rain. The nerve cells, like the corn, have a limited chance to grow & form & if nutrients don't come in time it dies.Nerves will not repair or regenerate after they die. Pvl reflects such an injury. Good basic nutrition allows you to maximize any remaining nerves, but extra herbs & supplements just create expensive urine. ...Read more

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What is the treatment for periventricular leukomalacia?

Dr. F. discussed: acute care. At the time of discharge from the NICu, an MRI of the brain is most predictive of outcome. The NICU will give you contact info for your state's Early Intervention Program. Enroll your baby & start services right away, even though you probably won't see any signs of motor impairment, as Occupational & Physical Therapy can minimize development of abnormal motor patterns. ...Read more

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What is periventricular leukomalacia?

What is periventricular leukomalacia?

PVL is caused by : lack of blood flow & oxygen to the white matter around the ventricles of the brain, an area most susceptible to damage around the end of the 2nd trimester. Severity of impairment varies widely, but isn't seen right away. Start Early Intervention therapy at 4-6 weeks as "Early Prevention" for optimal outcome. See: http://cerebralpalsy.org/about-cerebral-palsy/cause/periventricular-leukomalacia/ ...Read more

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What are the tests for periventricular leukomalacia?

Visible on US or CT: An ultrasound done through the soft spot will often detect pvl. Ct or MRI might also be helpful but the cranial ultrasound is easy to do & requires little preparation or stress on the patient so it is the more common study for this dx. ...Read more

See 1 more doctor answer
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What are the symptoms of periventricular leukomalacia?

Symptoms: Periventricular leukomalacia is a condition that mostly affects preterm infants. The hallmark symptom present in these children is a bilateral spasticity of the lower limbs. ...Read more

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What is the definition or description of: Periventricular leukomalacia?

What is the definition or description of: Periventricular leukomalacia?

PVL: Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder. ...Read more

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I am a basket case. My son has periventricular leukomalacia. Can you tell me something about it?

Discriptive term: Pvl is used to describe changes in the appearance of the brain substance that is adjacent to the ventricles of the brain (spinal fluid containing sacs in the middle). This occurs when blood flow or oxygen delivery to those sites was interupted and injury occured. Outcome is variable & movement disorders& motor delay are common. Therapy will often improve outcome. Developmental followup is a must. ...Read more

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Would like to know what immediate action can be taken for a child (11 yrs ) suffering from "periventricular leukomalacia" has an attack of fits. ?

Would like to know what immediate action can be taken for a child (11 yrs ) suffering from "periventricular leukomalacia" has an attack of fits. ?

Loss of blood flow &: oxygen causes death of white matter around the fluid-filled ventricles of the fetal brain, often between 26-42 wks. More common in "preemies", some causes are infection, maternal cocaine or meth use & bleeding in the ventricles. Pediatric neurologists treat Spastic Cerebral Palsy & Seizures. Special Education is needed for Intellectual Disability or Specific Learning Disability. See below. ...Read more

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What's the prognosis for periventricular leukomalacia (pvl) in a baby?

What's the prognosis for periventricular leukomalacia (pvl) in a baby?

See below: The prognosis varies. It depends on the severity of the pvl, and any other problems. The child should have his/her development followed closely. They may benefit from early intervention services, as well. ...Read more

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Are there good alternative medicines for kids with periventricular leukomalacia?

Are there good alternative medicines for kids with periventricular leukomalacia?

No: Periventricular leukomalacia is a condition where brain tissue has been lost in so-called "water-shed" areas. Since the tissue is gone, there is no treatment per se, although one may need to treat associated disorders, such as muscle stiffness or dysfunction, with medical or non-medical therapies. ...Read more

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What is the treatment for periventricular leukomalacia?

Dr. F. discussed: acute care. At the time of discharge from the NICu, an MRI of the brain is most predictive of outcome. The NICU will give you contact info for your state's Early Intervention Program. Enroll your baby & start services right away, even though you probably won't see any signs of motor impairment, as Occupational & Physical Therapy can minimize development of abnormal motor patterns. ...Read more

See 1 more doctor answer
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How common is periventricular leukomalacia in babies born full term?

How common is periventricular leukomalacia in babies born full term?

Uncommon: Very uncommon. Periventricular leukomalacia, or white matter pathology, represents some pathological process has occurred or is occurring. This would require an understanding of cause and perhaps an action plan wrt treatment, if possible. ...Read more

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Can a combination of omega fatty acids 3, 6, 9 along with spirulina be helpful in treating "periventricular leukomalacia" for a kid of 11 years?

Unlikely to matter: Pvl is similar to having the corn crop die when it doesn't get rain. The nerve cells, like the corn, have a limited chance to grow & form & if nutrients don't come in time it dies.Nerves will not repair or regenerate after they die. Pvl reflects such an injury. Good basic nutrition allows you to maximize any remaining nerves, but extra herbs & supplements just create expensive urine. ...Read more

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What is periventricular leukomalasia (pvl)?

What is periventricular leukomalasia (pvl)?

A problem...: Pvl as defined above is an type of brain injury that occurs in infants; the tissues surrounding the "ventricles"(which house fluid) are damaged leading to 'holes'. The problem arises in that there is no curative treatment for this disorder as of today; treatment focuses on helping the baby/child cope with the developmental and neurological consequences of the disorder in the first 2 years of life. ...Read more

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