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Doctor insights on: Periventricular Leukomalacia

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Dr. Krishna Kumar
36 doctors shared insights

Periventricular Leukomalacia (Overview)

Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder.


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I am a basket case. My son has periventricular leukomalacia. Can you tell me something about it?

I am a basket case. My son has periventricular leukomalacia. Can you tell me something about it?

Discriptive term: Pvl is used to describe changes in the appearance of the brain substance that is adjacent to the ventricles of the brain (spinal fluid containing sacs in the middle). This occurs when blood flow or oxygen delivery to those sites was interupted and injury occured. Outcome is variable & movement disorders& motor delay are common. Therapy will often improve outcome. Developmental followup is a must. ...Read more

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Dr. Krishna Kumar
36 doctors shared insights

Periventricular Leukomalacia (Overview)

Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder.


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What are the symptoms of periventricular leukomalacia?

What are the symptoms of periventricular leukomalacia?

Symptoms: Periventricular leukomalacia is a condition that mostly affects preterm infants. The hallmark symptom present in these children is a bilateral spasticity of the lower limbs. ...Read more

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What are the tests for periventricular leukomalacia?

What are the tests for periventricular leukomalacia?

Visible on US or CT: An ultrasound done through the soft spot will often detect pvl. Ct or MRI might also be helpful but the cranial ultrasound is easy to do & requires little preparation or stress on the patient so it is the more common study for this dx. ...Read more

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Can a combination of omega fatty acids 3, 6, 9 along with spirulina be helpful in treating "periventricular leukomalacia" for a kid of 11 years?

Can a combination of omega fatty acids 3, 6, 9 along with spirulina be helpful in treating "periventricular leukomalacia" for a kid of 11 years?

Unlikely to matter: Pvl is similar to having the corn crop die when it doesn't get rain. The nerve cells, like the corn, have a limited chance to grow & form & if nutrients don't come in time it dies.Nerves will not repair or regenerate after they die. Pvl reflects such an injury. Good basic nutrition allows you to maximize any remaining nerves, but extra herbs & supplements just create expensive urine. ...Read more

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What is the treatment for periventricular leukomalacia?

Dr. F. discussed: acute care. At the time of discharge from the NICu, an MRI of the brain is most predictive of outcome. The NICU will give you contact info for your state's Early Intervention Program. Enroll your baby & start services right away, even though you probably won't see any signs of motor impairment, as Occupational & Physical Therapy can minimize development of abnormal motor patterns. ...Read more

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What's periventricular leukomalacia?

What's periventricular leukomalacia?

Periventricular Leuk: Premature infant is prone to cerebral hemorrhage.Infarction of the periventricular white matter is called periventricular leukomalacia. ...Read more

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What is periventricular leukomalacia?

What is periventricular leukomalacia?

PVL is caused by : lack of blood flow & oxygen to the white matter around the ventricles of the brain, an area most susceptible to damage around the end of the 2nd trimester. Severity of impairment varies widely, but isn't seen right away. Start Early Intervention therapy at 4-6 weeks as "Early Prevention" for optimal outcome. See: http://cerebralpalsy.org/about-cerebral-palsy/cause/periventricular-leukomalacia/ ...Read more

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What are the tests for periventricular leukomalacia?

Visible on US or CT: An ultrasound done through the soft spot will often detect pvl. Ct or MRI might also be helpful but the cranial ultrasound is easy to do & requires little preparation or stress on the patient so it is the more common study for this dx. ...Read more

See 1 more doctor answer
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What are the symptoms of periventricular leukomalacia?

Symptoms: Periventricular leukomalacia is a condition that mostly affects preterm infants. The hallmark symptom present in these children is a bilateral spasticity of the lower limbs. ...Read more