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Doctor insights on: Perivascular Lymphocytic Dermatitis

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Vacuolar interface dermatitis, tight superficl perivascular & periadnexial lymphocytic infiltrate, mild incr. In dermal mucin. No fungus.-rash biopsy.?

Vacuolar interface dermatitis, tight superficl perivascular & periadnexial lymphocytic infiltrate, mild incr. In dermal mucin. No fungus.-rash biopsy.?

Varied possibilities: These findings suggest several possible entities. Based on this description of biopsy findings diagnoses including connective tissue disease such as lupus erythematosus may be considered, as well as a drug reaction. However, the only way to accurately make a diagnosis is to correlate the biopsy findings with the clinical presentation and other symptoms a patient may be having. ...Read more

Dr. John Chiu
2,663 Doctors shared insights

Rash (Definition)

A skin rash is a symptom in which a person has changes on part or all of his skin, such as color changes, bumps, blisters, oozing, peeling, ...Read more


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Derm biopsy report: mild vacuolar dermatitis with scattered papillary dermal interstitial eosinophils and perivascular lymphocytes. What does it mean?

Derm biopsy report: mild vacuolar dermatitis with scattered papillary dermal interstitial eosinophils and perivascular lymphocytes. What does it mean?

Biopsy report: You need to discuss this with the person who did the biopsy and ordered the report. They are in the best position to interpret it. We don't even know where the biopsy was from. ...Read more

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Hi doctors, can you tell me what is perivascular and interstitial dermatitis with eosinophils and slight spongiosis?

Hi doctors, can you tell me what is perivascular and interstitial dermatitis with eosinophils and slight spongiosis?

Since that is a: Pathology diagnosis, you need to take your results to a dermatologist. Comparing the pathology with the clinical findings will get you a correct diagnosis ...Read more

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Can perivascular dermatitis leave thinng scarring severely sensensitve skin on glans and under penis for years biospy said that it was but never ictch?

Can perivascular dermatitis leave thinng scarring severely sensensitve skin on glans and under penis for years biospy said that it was but never ictch?

Here are someā€¦: Clinically, at least, I would like to congratulate for not being skin malignancy. Perivascular dermatitis is merely a descriptive term as seen on the microscope. But how this may be correlated with clinical picture is still unclear and how to manage your current condition is also uncertain. In facing current dilemma, One has to consider the balance between medical necessity and pro-possibility. ...Read more

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Does dermitis and ecmeza on penis cause itching it cracked on glans and under leaving scarring no itching ever biospy said perivascular dermatitis???

Does dermitis and ecmeza on penis cause itching it cracked on glans and under leaving scarring no itching ever biospy said perivascular dermatitis???

Non-specific: These are all non-specific terms. Perivascular dermatitis on biopsy is not a diagnosis. It is descriptive only. Cushing's syndrome? Iatrogenic or primary???? Treated? You need the most skilled attention to this. I hope you have a good dermatologist. ...Read more

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What is mild superficial perivascular lymphocytic inflammation?

What u r describing: Sounds like a lymphocytic dermatitis; these rashes can be caused by reactions to medications or alternatively other allergic reactions. Speak with your physician for further insight. ...Read more

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Hi, My skin biopsy shows "hyperkeratosis and acanthosis of the epidermis and in dermis perivascular lymphocytic infitrate" will Ciclosporin help me?

Hi, My skin biopsy shows "hyperkeratosis and acanthosis of the epidermis and in dermis perivascular lymphocytic infitrate" will Ciclosporin help me?

Not specific enough: This sounds like a fairly benign pathologic description, so I doubt you would need cyclosporine, unless there is other information, or there has been no response to more benign therapies ...Read more

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Causes of modest superfical perivascular lymphocytic infiltrate? Vessels show reactive changes, no necrosis, no eosinophils and no neutrophils seen.

Causes of modest superfical perivascular lymphocytic infiltrate? Vessels show reactive changes, no necrosis, no eosinophils and no neutrophils seen.

Skin inflammation: This indicates an inflammatory process involving the skin, but it doesn't point to a specific cause. You will need to follow with your dermatologist regarding the cause and treatment of your condition. ...Read more

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Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes. Does thismean allergic vasculitis?

Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes. Does thismean allergic vasculitis?

No: There is no involvement of the blood vessels themselves- thus not vasculitis by definition. This is a very common skin biopsy finding which has no diagnostic meaning other than ruling out a more serious condition. ...Read more

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My skin biopsy says mild perivascular lymphcytic infiltrate. Mild mucopolysacharide like material in papilary dermis extending to skin. What is this?

My skin biopsy says mild perivascular lymphcytic infiltrate. Mild mucopolysacharide like material in papilary dermis extending to skin. What is this?

Nonspecific.: This is a very nonspecific picture. It can be seen in many common skin conditions, such as sunburn, eczema, and medication rashes. The fact that the pathologist did not list a diagnosis indicates that the appearance is too nonspecific to pinpoint a cause, so (s)he just described what (s)he saw. ...Read more

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Lymphocytic dermatitis where do you get this?

Lymphocytic dermatitis where do you get this?

1 cause is medicine: Rashes due to medications and other types of allergic reactions are two causes (of many) which can cause a lyphocytic dermatitis. I would suggest you speak with a physician to obtain further information on this condition. ...Read more

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"there is an accompanying mild perivascular & interstitial acute & chronic infiltrate." what does that mean in layman's terms? (vulvar biopsy)

"there is an accompanying mild perivascular & interstitial acute & chronic infiltrate." what does that mean in layman's terms? (vulvar biopsy)

Not much: It's a little bit inflamed & has been for some time. These mild changes may be more helpful to the dermatologist who may be trying to make a specific diagnosis -- or just a tipoff on "nothing to worry about." your physican will give you the final word. ...Read more

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What's the difference between white matter lesions and perivascular spaces? There's a possibility to one mimic the other?

What's the difference between white matter lesions and perivascular spaces? There's a possibility to one mimic the other?

MRI findings: Sometimes perivascular spaces look like changes in the white matter. They are terms used to describe nonspecific findings. White matter lesions are normally discrete, not nearby blood vessels, and sometimes have MRI characteristics that help us know they are due to a stroke or MS. It is possible that one looks like the other, depending on what kind of MRI is done, and who is interpreting it. ...Read more

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Enlarged perivascular spaces on Mri. What does it mean? And why would the radiologist report something like that?

Enlarged perivascular spaces on Mri. What does it mean? And why would the radiologist report something like that?

Part of their job: Radiologist would report anything that is not considered normal. More importantly, you should talk to the doctor ordering the test to see if your symptoms match the abnormality seen on the images. In most cases, many variations of the normal are just that, variations without any significant pathology. Feel gokd ...Read more

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My son had a skin biopsy (7 yrs). N the report says perivascular lymphoctic infiltrate with extravasated rbc. I need to know what does it mean.

My son had a skin biopsy (7 yrs). N the report says perivascular lymphoctic infiltrate with extravasated rbc. I need to know what does it mean.

Possibly viral: Many reactions to viruses have histology (microscopic appearance) with this description. Would need to see the entire report and slide to be sure. ...Read more

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Could a dilated perivascular space shown on MRI be a marker for ms? The size is same since 2010.

Could a dilated perivascular space shown on MRI be a marker for ms? The size is same since 2010.

Not at all: Nondiagnostic for any disease. Your description of the MRI is NOT consistent with MS. ...Read more

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I had bilat. Mastectomy last Nov. On non cancer side path. Stated" perivascular chronic inflammation". Could that cause problem during the surgery?

I had bilat. Mastectomy last Nov. On non cancer side path. Stated" perivascular chronic inflammation". Could that cause problem during the surgery?

Likely not: This is likely a chronic thing. This may be precancerous development. You need to see the doctor that did the surgery and have the surgeon talk to the pathologist. If there is no cancer there is no cancer. The chronic vascular phenomena may be just that and no more. Get peace of mind also if you talk to your cancer doctor. Should not cause a problem during surgery. Best wishes ...Read more

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Mri no contrast "incidental superficial left ventral pontine tegmentum tiny 3 mmt2 hyper intensity in keeping with a perivascular space"? Help please!

Mri no contrast "incidental superficial left ventral pontine tegmentum tiny 3 mmt2 hyper intensity in keeping with a perivascular space"? Help please!

If correct, no prob: Perivascular spaces are often normally seen in the brain on mri. If the interpretation of your MRI is correct, a perivascular space is a normal finding. ...Read more

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Affected by perivascular sheathing 4years ago (re).Now it seems my vision is foggy and it started on left eye too. Specialists in our city found nothing?

Affected by perivascular sheathing 4years ago (re).Now it seems my vision is foggy and it started on left eye too. Specialists in our city found nothing?

Retinal vasculitis: May cause perivascular sheathing or thickening of either the veins or arteries in the retina. Autoimmune vasculitis is a frequent concern. Any of these diseases can cause such inflammation which can damage the retina and cause permanent visual loss. A retina specialist who can conduct a Fluorescein angiogram can help. Also get TB test. Many autoimmune diseases have manifestations in the retina. ...Read more

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What are mildly prominent dilated perivascular spaces on a brain mri?

What are mildly prominent dilated perivascular spaces on a brain mri?

Normal: Perivascular (also known as perivenular or virchow-robin) spaces can be seen at any age and have bizarre or asymmetric configurations. They tend to become more numerous and larger as a person ages, and are benign.

The only concern is if they are confused for a cystic space caused by a disease. Knowing where v-r spaces are likely to develop makes it much easier to accurately diagnose them. ...Read more

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Superficial left pontine tegmentum tiny 3 mm t2 hyperintensity in keeping with a perivascular space on mri. Could this be from a stroke?

Superficial left pontine tegmentum tiny 3 mm t2 hyperintensity in keeping with a perivascular space on mri. Could this be from a stroke?

Stroke: Not to worry. Perivascular spaces (Virchow-Robin spaces) are normal and not caused by a stroke. They can occur throughout the brain. The perivascular spaces vary in size (up to 5 mm) and are associated with arteries in the brain. ...Read more

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Help understand skin biopsy result: "There is a sparse perivascular lymphohistiocytic inflammatory infiltrate. CD117 highlights only a few scattered mast cells. Diagnosis: Mild superficial perivascular infiltrate." Anything of concern here?

Help understand skin biopsy result: "There is a sparse perivascular lymphohistiocytic inflammatory infiltrate. CD117 highlights only a few scattered mast cells. Diagnosis: Mild superficial perivascular infiltrate." Anything of concern here?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the findings listed in the report are non-specific and non-diagnostic. Do you have any symptoms? Why was the biopsy done? ...Read more

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My head MRI shows I have enlarged perivascular spaces and a cyst in pineal gland should I consult a neurosurgeon?

My head MRI shows I have enlarged perivascular spaces and a cyst in pineal gland should I consult a neurosurgeon?

Not neccessarily: The neurosurgeon will not treat either of those conditions. They are relatively common findings and typically benign. Some surgeons will arrange for a followup MRI to assure that the cyst is not growing, but this is cost ineffective. The vast majority of the cysts are benign and enlarged perivascular spaces has no significance. ...Read more

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What does this mean: flow void is identified in major intracerebral blood vessels. Small prominent perivascular spaces in inferior basal ganglia bil?

What does this mean: flow void is identified in major intracerebral blood vessels. Small prominent perivascular spaces in inferior basal ganglia bil?

Doctorspeak: This is doctorspeak for normal findings on the MRI.
A flow void indicates there is blood flow. Lack of a flow void would be bad. This is normal.
Prominent perivascular spaces are likewise a benign (nothing to worry about) finding. ...Read more

Dermatitis (Definition)

Dermatitis means inflammation of skin. Contact dermatitis, allergic contact dermatitis and seborrheic dermatitis are ...Read more


Dr. Cornelia Franz
1,059 Doctors shared insights

Rash (Definition)

A rash is a change to skin condition which can affect color, appearance, or texture. It may or may not ...Read more