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Doctor insights on: Periactin For Sleep

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Is it safe to take 4mg of lunesta (eszopiclone) in conjunction with 4mg of periactin to help me sleep. I suffer from ptsd, chronic insomnia, adhd.

Is it safe to take 4mg of lunesta (eszopiclone) in conjunction with 4mg of periactin to help me sleep. I suffer from ptsd, chronic insomnia, adhd.

Heavy: This is a powerful regimen for sleep. I think that the use of eszoplicone chronically may lead to cognitive disturbances that are hopefully reversible with discontinuation. Additionally, antihistamines used chronically can lead to weight gain or cognitive impairment as well. Talk with your doctor about any concerns and as always try to implement sound sleep hygiene before you go to sleep! ...Read more

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Dr. Heidi Fowler
4,987 doctors shared insights

Sleep (Definition)

Sleep is a topic that involves concepts such as how long it takes to fall asleep, how many times one wakes up at night, how many hours one sleeps at night, sleep stages, ...Read more


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On cyproheptadine for headaches. Take half a 4mg tab at bedtime. But now I'm sleeping through my alarms and constantly feel exhausted everyday.

On cyproheptadine for headaches. Take half a 4mg tab at bedtime. But now I'm sleeping through my alarms and constantly feel exhausted everyday.

Sleepiness is: A known side effect of cyproheptadine because it's an antihistamine like Benadryl (diphenhydramine). There are several other options for migraine medicine. Your doctor can help you pick one without this side effect. ...Read more

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Can periactin (cyproheptadine hydrochloride) make you gain weghit!?

Can periactin (cyproheptadine hydrochloride) make you gain weghit!?

Absolutely yes: Periactin (cyproheptadine hydrochloride) (cyproheptadine) is a very effective anti-histamine. It is quite sedating and increased appetite is and associated weight gain are well-known side effects. ...Read more

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How can I use periactin (cyproheptadine hydrochloride) to gain weight?

How can I use periactin (cyproheptadine hydrochloride) to gain weight?

Discuss w your DR.: Per Drugs.Com (regarding use of periactin): 'In healthy, thin individuals, weight gain of 4 kg in 56 days has been reported with a dosage of 12 mg orally per day.' ...Read more

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How long to develope tolerance to cyproheptadine periactin (cyproheptadine hydrochloride)?

How long to develope tolerance to cyproheptadine periactin (cyproheptadine hydrochloride)?

Highly variable: It may be a few weeks or months but I have one patient with chronic hives who has been on the same dose for over four years. ...Read more

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Does periactin (cyproheptadine hydrochloride) make you gain weight? Please, need some answers?

Does periactin (cyproheptadine hydrochloride) make you gain weight? Please, need some answers?

Yes, it can: Periactin (cyproheptadine hydrochloride) (cyproheptadine), is mainly used as an antihistamine, particularly for cold-induced urticaria (welts caused by cold objects). It also has effects on the brain, including sedation and increase in appetite, leading to weight gain. ...Read more

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Are there any alternates similar to periactin (cyproheptadine hydrochloride) (cyproheptadine)?

Could be several but: It depends why you are taking it...This is an antihistamine which helps itching. But, it can make you sleepy, or even hungry(sometimes given to increase appetite). There are several over the counter anti-histamines(which you to be available only by prescription) which are very helpful --allegra, zyrtec, claritin (loratadine). Read the labels and see if they help you. If not check with the dr. Who prescribed it. ...Read more

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Which are side effects of periactin (cyproheptadine hydrochloride)?

Which are side effects of periactin (cyproheptadine hydrochloride)?

Some common: Many people experience an increase in appetite (leads to weight gain) and some experience drowsiness. This old antihistamine has been replaced by others that tend to be as effective with less side effects. ...Read more

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Would periactin (cyproheptadine hydrochloride) be used in the same capacity as reactin?

Would periactin (cyproheptadine hydrochloride) be used in the same capacity as reactin?

Reactin vs periactin (cyproheptadine hydrochloride): No they are not similar in any way.Reactin is cetrizine sold in canada under name of reactin, it is once a day allergy medicine, it is second genaration allergy med, and is not as sedating as first generation like benadryl, (diphenhydramine) and periactin periactin is a first generation antihistamine, is sedating and has to be taken 3or4 time a day, generic name cycloheptadine. ...Read more

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After ceasing to take periactin, (cyproheptadine hydrochloride) my behaviour has changed, could be withdrawal?

After ceasing to take periactin, (cyproheptadine hydrochloride) my behaviour has changed, could be withdrawal?

Not withdrawal: Periactin (cyproheptadine hydrochloride) (cyproheptidine) makes you sleepy. Sometimes it makes you hungry but it's not habit-forming or addictive. If you feel more alert, less drowsy, have more energy, and decreased appetite that's just the effects of this classical antihistamine wearing off. ...Read more

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What is the definition or description of: Periactin allergy?

What is the definition or description of: Periactin allergy?

Usually not aproblem: Periactin or Cyproheptadine is used to treat allergies or sometimes given to increase appetite since it has a this side effect. Cold urticaria commonly responds to this also. Allergic reactions to this medication are not commonly observed. ...Read more

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Can i get periactin (cyproheptadine hydrochloride) without prescription?

Not in the USA: It is only available by prescription...But Allegra , zyrtec, and Claritin (loratadine) are good, over the counter antihistamines (which used to only be available by prescription). ...Read more

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Could i get my doctor to prescribe me cyproheptadine (ciplactin or periactin)?

Could i get my doctor to prescribe me cyproheptadine (ciplactin or periactin)?

Yes: Both are older antihistamines. They do cause quite a bit of sedation and can cause confusion in the young, elderly and enhance sedative properties of other drugs. Action is no better than 2nd generation non sedating antihistamines, with the exception of some anxiety relieving effects due to sedation. ...Read more

Dr. Heidi Fowler
37 doctors shared insights

Cyproheptadine Hydrochloride (Definition)

Cyproheptadine hydrochloride is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Michael Gabor
40 doctors shared insights

Periactin (Definition)

Periactin is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more