Doctor insights on:
PPIs;H2blockers: Proton pump inhibiters like omeprazole, nexium, Prevacid or dexelent by itself or in combination with h2 blockers like ranatadine; Reglan (metoclopramide) will relieve the symptoms of non acid laryngopharyngeal reflux.Robinul forte can also be used as it cuts down the pepsin secretion to some extent. Along with that life style modifications, elevating the head end of bed avoidfoods like dairy, wheat;eggs, wt loss. ...Read more
Amino acid links: Pepsin is an enzyme whose zymogen (pepsinogen) is released by the chief cells in the stomach and that degrades food proteins into peptides. Pepsin is most efficient in cleaving peptide bonds between hydrophobic and preferably aromatic Amino Acids such as phenylalanine, tryptophan, and tyrosine. ...Read more
So theoretically - if you did not eat any protein - then surely the pepsin would not be activated?
None: Pepsin, the powerful enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, or dairy products in the stomach. Once in the small intestine, the ph is higher rendering pepsin inactive in further digestion of proteins. Absorption of proteins occurs primarily in the small intestine. ...Read more
Pepsin: Pepsin operates best in a very acid environment. It's optimal pH is 1.5, which is approximately the same pH as the stomach environment where the acid has been secreted. Hope that helps. ...Read more
Stop it.: There is no good research that I can find that says this even works! Since there is no unbiased information about the product, then info on side effects will also likely be biased. Stop it. If your diarrhea does not improved, see your doc. Eat okra, the vegetable, instead of a pill, instead. It's high in fiber and has other good things in it. ...Read more
Aloe is well-known for soothing burns and can also soothe inflamed and irritated mucous membranes.
There are many aloe juices out there and some are better than others. This article tells how to make your own:
Reliable brands include Lily of the Desert and Pharm-Aloe ...Read more
Good question: The enzymes are not exact, but they act similarly. Papya has been a traditional aid to digestion. However, how equivalent the papaya pepsin is to your natural enzyme I do not know. ...Read more
NO.: Betaine is only used for patients with homocysteinuria (a genetic metabolic defect) and occasionally xerostomia (inability to produce saliva) or fatty liver disease. Betaine can cause nausea, diarrhea, body odor, and severe GI distress. If your child is having digestive issues, please see her doctor for proper evaluation and treatment. ...Read more
Would Pepsin GI (8MG Zinc with 29.5MG L-Carnosine) be a helpful supplement to take if I currently have gastritis?
Possibly, but: PepZin is a compound of L-carnitine and Zinc marketed in Japan for treatment of stomach distress and peptic ulcer disease. Studies support it's healing effect in a number of gastric conditions. If you've self diagnosed your condition as gastritis you should check with a physician to be sure you don't have an ulcer or H.pylori related gastritis. Most U.S. physicians are not familiar with PepZin. ...Read more
A rapid spit test found pepsin in my saliva (35ng/ml). This is meant to be low, but should I be worried? Is some extraesophageal reflux normal?
Some is normal: It is believed that everyone has some extra esophageal reflux. It is only a problem when it starts causing symptoms like phlegm in the throat, throat clearing, difficulty swallowing, lump in the throat sensation, hoarseness, and sore throat to name some of the common symptoms. ...Read moreSee 1 more doctor answer
I am having burning diarrhea after taking Betaine HCL with pepsin for the first time before breakfast. Should I discontinue taking or is this normal?
Yes: Yes pepsin and other enzymes called proteases are activated by the acid in the stomach . The proteases break apart the Amino Acid links within the chain that makes a protein. The freed Amino Acids are then absorbed by the small intestines. Some small chains of Amino Acids are also broken down in the small intestine or absorbed directly. ...Read moreSee 1 more doctor answer
A nutritionist has suggested i go on betaine hydrochloride with pepsin tablets upping dose each time until i get burning sensation. Is it safe?
Yes: Betaine hydrochloride will kill silent infections and doing a detox similar to yours will improve lymphatics. Additionally if there is biliary sludge betaine hcl detox will improve bile flow. Pepsin will improve digestion. If there is irritation use bromelain in addition which will heal the irritation and ulcerations. We use betaine hcl detox for lyme disease - upto 10gm-15gm twice daily. ...Read more
I've heard i can take glycopyrrolate to help reduce pepsin for non acidic reflux but do I have to be careful taking with omeprazole and domeridone ?
I don't advise it: If you are taking domperidone for gastroparesis, Glycopyrrolate is likely to make it worse. It slows down bowel function and causes constipation and bloating. It has major anticholinergic side effects which you can review at www.Drugs.Com these side effects slow down intestinal function and gastric function. ...Read more
Pepsin and Cancer : Some well-reviewed studies have linked the action of pepsin, a natural enzyme produced in the stomach to promote digestion of proteins, to increased promotion of some oral and laryngeal cancers. Some popular web sites tout the positive effects of pepsin, while others warn of the over use of anatscids that actually may interfere with digection. It is best to consult a gastroenterologist. ...Read more
I'm weening myself off Prevacid (lansoprazole) with the help of a Betaine/Pepsin HCL pill every morning. It helps but I now have heart palpitations. Side effect?
Betaine HCL/pepsin: There are no reported cases on palpitations but theoretically the pepsin/HCL combo could have negative vagal feedback ( vagus stimulation produces pepsin on our stomach). The vagus nerve via parasympathetic stmulation slows the heart and if it is inhibited there could be increase heart rate. You could try stopping the meds and seeing if palpitations stop. Check B6, folate (folic acid) ,B12 .F/U with doc. ...Read more
I get excessive sticky white mucus build up in the larynx area, is this likely to be pepsin, bile or acid, it never burns my throat ?
Throat mucus: Throat mucus can come from chronic allergies either in the air or also from foods you're eating. Frequent causes are dairy products. Mucus is not the same as pepsin, bile, or acid -- but if you have gerd your throat can be irritated. Chronic cough can come with this. Please discuss this with your physician. ...Read more
Can pepsin and acids in throat caused by LPR, get into both parotids and cause pain, soreness and stinging upon eating? No apparent swelling.
Unlikely: I think that would be extremely unlikely, but one can "never say never". It also depends on how the LPR was diagnosed. If you haven't had a formal pH study, you should consider if since your having problems. There are woress studies for 48 hours that measure acid only, and 24 hr studies that measure acid and non-acid reflux. Consider a consult with a GI doctor interested in esophageal testing. ...Read more
Is Alkaline water effective in eliminating pepsin effect in sore throat due to laryngo pharyngeal reflux . ?
There are none...: Even the strongest opiates only "take the edge off" for people in chronic pain. Meds are only one part of dealing with the pain. A useful tool, but pain is so necessary for survival that we are not "allowed" to monkey with it much. In acute pain, the transition from miserable to less miserable can be great. In chronic pain, it's just part of the plan. ...Read more
So call your doc: This is the HT public information site.We are thousands of volunteer docs based primarily in the US who answer medical questions.We do not offer treatments. State medical boards require a physician/patient relationship,a retrievable record,recent exam with vital signs for prescribing.Failure to do so can lead to loss or restriction of license. It may seem minor to you but it is not. ...Read moreSee 1 more doctor answer
Sometimes: Sometimes they are. For the most part, expired drugs simply lose potency once past their expiration date. There are, however, some drugs that actually become harmful if taken after they expire. As such, it is best to throw out any medications you have after a year. ...Read more
ASPRIN: Actually no one has decided on 'safest'. Asprin has been around since before you were born and unless you take too much (yes, too much of anything isnt good) most people are okay with it. If the pain it too severe for asprin you need to know what causes it. Good diagnosis is called for. See the dr. ...Read more
Applies to skin: Topical just refers to how a medication is applied. In this case to the skin and is meant to treat local skin problems. Some meds are applied to the skin but are meant to be absorbed into the body in which case we use the term "transdermal" since it is meant to pass through the skin to affect the whole body. ...Read more
Why R you depressed?: If your depression is affecting your life and/or those around you and you have trouble dealing with it or not knowing how to etc..It is very reasonable to seek help, either from a therapist, your physician/nurse, or both. Psychotherapy may be adequate for some, others may need both meds (many choices, depending on your symptoms/needs) and therapy. Consult doc. Good luck. ...Read moreSee 2 more doctor answers