Doctor insights on:
No firm rule.: Cyclophosphamide carries a risk of causing cancer. Bladder cancers and leukemia would be the most common. The risk is related to dose and duration of treatment. Case reports suggest treatment after 4-5 years may be more dangerous. If the drug is effective, the benefit may outweigh the risk, but concern should be raised if the tratment lasts more than 1-2 years. ...Read more
My mom has pemphigus foliaceous. She now has diabetes and hemorrhoids from the steroids. Her diet is solely veggies! How to soften stools natural/OTC?
Need more info: This is a complicated problem and there is no quick answer. Your mom must make an appointment with the physician who is treating her diabetes who can make intelligent & important decisions to set things better and keep her health on the correct track both medically and nutritionally. ...Read more
Not yet: There is not yet a cure for pemphigus vulgaris, but the condition is controllable with immunosuppressive treatment. The usual treatment is with corticosteroids, which are often started at high doses, together with immunosuppressive drugs (azathioprine, cyclophosphamide, cyclosporin, methotrexate, etc.). New medicines called biologics (such as rituximab) are being studied, for treating pemphigus. ...Read more
No one best medicine: Prednisone is the drug most commonly used to treat pemphigus. Other immunosuppressive agents are used either with or instead of Prednisone depending upon the individual's response & tolerance. All of these medications have potentially significant adverse effects so management by an expert in this disease and in using these drugs is vitally important. What's best for one is not best for another. ...Read more
Blisters: This is a cruel disease in which the patient makes antibodies against a protein that holds the skin cells together. This is one of the most serious diseases in dermatology practice, and calls for a lasting relationship with one who you trust. Appearing suddenly, it may warn of a cancer deep in the body. Good luck. ...Read more