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Doctor insights on: Pemphigus

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Dr. Lindsay Strowd
127 doctors shared insights

Pemphigus (Overview)

Pemphigus is a group of rare autoimmune skin conditions characterized by blistering lesions in the skin and mucosal membranes such as in the mouth.


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What causes pemphigus?

What causes pemphigus?

Autoimmune antibody: A glycoprotein the binds skin cells (keratinocytes) together is the reported target of auto-immune antibodies in pemphigus. ...Read more

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Dr. Peter Kurzweil
44 years in practice
16M people helped
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Dr. Lindsay Strowd
127 doctors shared insights

Pemphigus (Overview)

Pemphigus is a group of rare autoimmune skin conditions characterized by blistering lesions in the skin and mucosal membranes such as in the mouth.


2

2
What are the most common symptoms of pemphigus?

What are the most common symptoms of pemphigus?

Pemphigus: Severe autoimmune disease where your antibodies attack the dermis and epidermis cells (aka skin). You need to see a dermatologist about this asap. Risks include infection, dehydration, and ultimately death if not treated appropriately. ...Read more

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Dr. Peter Kurzweil
44 years in practice
16M people helped
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My cousin was diagnosed with pemphigus vulgaris.She is on steroid and imuran therapy since last two years but not recovering completely.Please help.

My cousin was diagnosed with pemphigus vulgaris.She is on steroid and imuran therapy since last two years but not recovering completely.Please help.

Tough one: You need an experienced dermatologist that deals with immune skin diseases and these are usually found in academic centers. If your friend lives close to a tertiary care referral hospital, i would look there. They know about all the new studies going on in the field and can try different treatment options. ...Read more

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What are the tests for pemphigus?

What are the tests for pemphigus?

Biopsy: The diagnosis of pemphigus is made by history and examination of characteristic lesions on the skin or in the mouth and throat. A definitive diagnosis is made by biopsy with examination of the tissue by a dermatopathologist. ...Read more

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What is the best medicine to treat pemphigus. I have heard about mestinon working?

What is the best medicine to treat pemphigus.  I have heard about mestinon working?

Pemphigus: Phemphigus vulgaris is a potentially fatal autoimmune mucocutaneous blistering disease. Conventional therapy consists of high-dose corticosteroids, imminosuppressove agents, and intravenous immune globulin. Studies show that the biologic Rituximab and intravenous Immune Globulin is very effective with refractory pemphigus vulgaris. Mestinon is not as effective as rituximab. ...Read more

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I have pemphigus vulgaris and I am treating it with mycophenolate and prednisone. Currently, I have scabs on my scalp that apears to not heal. What is causing this not to heal? The prednisone?

Pemphigus: Your pemphigus condition could be causing sores/scabs in your scalp just as it could be causing other sores/scabs in other bodily areas. Follow-up with your dermatologist. Prednisone is anti-inflammatory and should generally help your pemphigus and not be causing spontaneous sores/scabs in your scalp. ...Read more

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Dr. Peter Kurzweil
Board Certified
44 years in practice
16M people helped
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What is the treatment for pemphigus?

What is the treatment for pemphigus?

No one best medicine: Prednisone is the drug most commonly used to treat pemphigus. Other immunosuppressive agents are used either with or instead of Prednisone depending upon the individual's response & tolerance. All of these medications have potentially significant adverse effects so management by an expert in this disease and in using these drugs is vitally important. What's best for one is not best for another. ...Read more

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Can accupuncture cure pemphigus vulgaris? Need expert opinions!

Can accupuncture cure pemphigus vulgaris? Need expert opinions!

Doubt it: There is no scientific study showing that it works, thus the answer would be no. ...Read more

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Can pemphigus be hereditary?

Can pemphigus be hereditary?

Not really: Pv, pemphigus vulgaris, is not thought to be a genetic disease. However, a family history of pv might increase your risk. As of yet, no pv gene has been found that when mutated conveys the disease. ...Read more

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What causes pemphigus?

Autoimmune antibody: A glycoprotein the binds skin cells (keratinocytes) together is the reported target of auto-immune antibodies in pemphigus. ...Read more

Get help now ›

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Dr. Peter Kurzweil
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16M people helped
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