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Doctor insights on: Peginterferon Alfa Medication

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Will I be able to drink alcohol while taking the medications ribavirin and peg intron (peginterferon alfa 2b)?

Will I be able to drink alcohol while taking the medications ribavirin and peg intron (peginterferon alfa 2b)?

Not recommended: Ribavirin must be used together with a Peg-Intron to treat chronic hepatitis C. Do not drink alcohol while taking ribavirin. Alcohol can increase the risk of damage to your liver. Hope it makes sense? ...Read more

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What are the drugs those can interact with pegasys (peginterferon alfa 2a)?

What are the drugs those can interact with pegasys (peginterferon alfa 2a)?

Many: There is a long list of drugs that may interact. The main ones are
azathioprine, methadone, stavudine, telbivudine and theophylline. You should take to your doctor to make sure that your curent medicines do not interact with pegasys (peginterferon alfa 2a). ...Read more

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What are effects of pegasys (peginterferon alfa 2a)?

Depends: From a hepatitis c treatment standpoint, using Pegasys (peginterferon alfa 2a) in combination with Ribavirin and a protease inhibitor can have dramatic treatment effect (i.e. Lead to cure of hepatitis c depending on the stage of your liver disease). Now "side-effects" can range from "flu-like" symptoms to lab abnormalities, depression, rash, GI symptoms, anxiety/irritability, insomnia, etc. Discuss with your doctor. ...Read more

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What happens when I miss a dose of peginterferon alfa-2a ?

What happens when I miss a dose of peginterferon alfa-2a ?

Report it: When you miss a dose of peg interferon, you should report it to your treating physician. If it is just one dose, chances are you may have it injected later that day or week. If it is not feasible, i think you will still need to continue on with your treatment, as one dose is unlikely to change the trend you've had. Talk to you doc, though. ...Read more

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What are the potential side effects of peginterferon alfa-2a ?

What are the potential side effects of peginterferon alfa-2a ?

Talk to your doctor!: Some of the common side effects of Pegasys (peginterferon alfa 2a) (peg-interferon alfa-2a) are fatigue, depression, headache, fever, low white cell count, muscle pain and chills. However, there are potentially more serious side effects as well. The risk of developing side effects may depend on your other health problems. You should talk to your doctor. ...Read more

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Is juvederm safe while taking peginterferon and ribasphere. No mor detail

I would wait to use: Usually when being treated with peg interferon and ribavirin, you become immunosuppresed (i.e. Low immune system), so any other injections like juvederm can lead to local inflammation/skin reactions, infections and confound the other symptoms that you might be experiencing while undergoing treatment. I would wait to use juvederm until you finish your treatment therapy. ...Read more

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Any long term side effects from pegasys (peginterferon alfa 2a)?

Usually not: In general, once you have finished your treatment with pegasys, (peginterferon alfa 2a) side effects/symptoms that you were having during treatment slowly disappear, but can take up to 6 months and in some instances 1 year although rare. It can result in autoimmune disorders, although this is also rare. I would discuss your concerns with your treating physician for other rare long term side effects. ...Read more

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What are some common side effects of pegasys (peginterferon alfa 2a)?

What are some common side effects of pegasys (peginterferon alfa 2a)?

Flu-like symptoms: Although Pegasys (peginterferon alfa 2a) has been known to make psychiatric symptoms worse and cause some problems with bone marrow suppression (anemia, low white count, low platelets), the most common side effect is flu-like symptoms. ...Read more

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Can you tell me the difference between peginterferon alfa 2a & peginterferon alfa 2b?

Can you tell me the difference between peginterferon alfa 2a & peginterferon alfa 2b?

Drug names: Both are pegylated interferons. Peginterferon alfa 2a is made by roche branded Pegasys (peginterferon alfa 2a) and is a slightly larger molecule. Peginterferon 2B is made by schering and its dose is calculated based on body weight. The brand name is peg-intron.

These drugs have similar efficacy and side effects. ...Read more

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What is the usual procedure for preparing and injecting pegasys (peginterferon alfa 2a)?

What is the usual procedure for preparing and injecting pegasys (peginterferon alfa 2a)?

Simple Steps: Simple steps but all need to be done and it is best to have formal treating by a health care provider before starting. Basically it involves preparing the syringe and then drawing up the medication. Next you will need to find a spot on your abdomen or thigh and then inject into a pinched segment of skin. ...Read more

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Has anyone used peginterferon alpha 2B and temezolomide for melanoma?

Has anyone used peginterferon alpha 2B and temezolomide for melanoma?

Alone or in combo?: Both of these drugs have been used separately to treat metastatic or high risk melanoma. However, the combination of these two drugs must be considered experimental, without even knowledge of safe doses let alone efficacy. ...Read more

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Hi I'm 37 yr old and HCV + geno 3 ,should I go for interferon 2a + ribav or peginterferon 2a + ribav ,which is the best for me ,please advice.

Hi I'm 37 yr old and HCV + geno 3 ,should I go for interferon 2a + ribav or peginterferon 2a + ribav  ,which is the best for me ,please advice.

Harvoni: Well my dear your in luck. A new medication called Harvoni just came on the market. Its a combination of 2 very very effective medications (Ledipasvir-sofosbuvir). Its 1 pill a day, no interferon or ribaviron needed. The cure rate at 12 weeks is reported to be spectacular @ >94%. 12 weeks and your done. Ask your infectious disease doctor....its going to revolutionize Hep C treatment! ...Read more

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Long term after effect of pegasys (peginterferon alfa 2a) interferon?

Usually none: Most, if not all side effects usually resolve over 4-6 weeks. Rarely, some autoimmune conditions such as alopecia (loss of hair) if precipitated may not reverse. ...Read more

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Infergen use after pegasys (peginterferon alfa 2a) failure appropriate?

Not really: I am assuming you are asking about hepatits c treatment. Infergen is an old type of interferon. Data suggest that Infergen has little or no benefit after Pegasys (peginterferon alfa 2a) failure. There are new oral medications. These medications (pills) along with Pegasys (peginterferon alfa 2a) and Ribavirin has very good response rate, if you are infected with type i hepatitis c virus. Response rate is doubled from previous treatment. ...Read more

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What is the definition or description of: Peginterferon alfa 2b allergy?

What is the definition or description of: Peginterferon alfa 2b allergy?

Interferon SEs: Pegylated interferon alfa-2b, or PegIntron, acts as a cytokine agent to help rid the body of certain types of infections. It was a used in Hep C treatment in the past. Side effects can include headache, fatigue, mood changes, trouble sleeping, hair loss, nausea, pain at the injection site, fever, plus other more severe effects including psychosis, liver problems, blood clots, heart trouble etc. ...Read more

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What is the difference between pegasys (peginterferon alfa 2a) & peg-intron?

What is the difference between pegasys (peginterferon alfa 2a) & peg-intron?

Size of the molecule: Pegasys (peginterferon alfa 2a) is larger size and comes in solution where as pegontron comes as powder that needs to be reconstituted with saline before administration. Efficacy wise, Pegasys (peginterferon alfa 2a) may be marginally better. ...Read more

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Why are some slow in seeking approval for peg-intron and pegasys (peginterferon alfa 2a)?

Why are some slow in seeking approval for peg-intron and pegasys (peginterferon alfa 2a)?

Price: It is a very expensive medication!
insurance want to make sure it is indeed indicated before paying such a pricey medication. ...Read more

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What is the difference between pegasys (peginterferon alfa 2a) & pegintron in treatment of hcv?

What is the difference between pegasys (peginterferon alfa 2a) & pegintron in treatment of hcv?

Packaging...: Pegasys (peginterferon alfa 2a) and pegintron (peginterferon alfa 2b) are two drugs fda approved for treatment of chronic hepatitis c. They are slightly different in their chemical composition but studies indicate they are virtually equally effective in what they do and have very similar side effect profiles. Insurance usually drives which of the two is preferred on their formulary. ...Read more

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What is the difference between pegasys (peginterferon alfa 2a) & pegintron for treatment of hcv?

What is the difference between pegasys (peginterferon alfa 2a) & pegintron for treatment of hcv?

Very little: These are both long acting forms of pegylated interferon that can be injected once a week. Cure rates using each are similar. Pegasys (peginterferon alfa 2a) has been given a slight edge in cure rates by kaiser and veteran's admin studies as well as the uspstf. Most hepatitis c drug companies that combine their new drugs with interferon and Ribavirin use pegasys (peginterferon alfa 2a). But your provider will use what he/she is used to. ...Read more

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I was treated with pegintron & rebitol for HCV & my count increased from 130 to 460 at 48 th vial can I complete with pegasys (peginterferon alfa 2a)?

I was treated with pegintron & rebitol for HCV & my count increased from 130 to 460 at 48 th vial can I complete with pegasys (peginterferon alfa 2a)?

No benefit: The us preventative services task force recommends that pegintron and Pegasys (peginterferon alfa 2a) are similar enough that if someone did not achieve cure with pegintron, they should not attempt retreatment with Pegasys (peginterferon alfa 2a) since it will likely not help. Talk to your provider about new options in hepatitis c drug development and when they might be available for your genotype of hepatitis c. ...Read more

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Please answer! what kind of side effects remain after the completion of HCV treatment by pegasys (peginterferon alfa 2a) + ribaverine?

Please answer! what kind of side effects remain after the completion of HCV treatment by pegasys (peginterferon alfa 2a) + ribaverine?

Hepatitis C: Generally Pegasys effect is out of your system in few weeks and Ribavirin can stay in the system for upto 6 months.
After that there should be no side effects ...Read more

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Hepatitis c injection" peg intron (peginterferon alfa 2b) a" has many side effects. How can they be decreased.?

Hepatitis c injection" peg intron (peginterferon alfa 2b) a" has many side effects. How can they be decreased.?

Tylenol (acetaminophen) / Benadryl: You can try premedicating with tylenol (acetaminophen) and benadryl. Alternate injection sites. Get plenty of rest. ...Read more

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Will valerian root cause react badly with peginterferon alfa 2a and ribavirin for hep c?

Will valerian root cause react badly with peginterferon alfa 2a and ribavirin for hep c?

No...: Herbal remedies e.g. Valerian root, silymarin will probably not interfere with conventional antiviral treatment of hepatitis c - no studies i'm aware of. Conversely, there are no studies taking them will do any good - so you may want to save your money. Good luck! ...Read more

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My husband is treated for 3 months with Sovaldi, Peginterferon now his reports show HCV as non-detected.. but the Globulin value is 4.3.how to control?

My husband is treated for 3 months with Sovaldi, Peginterferon now his reports show HCV as non-detected.. but the Globulin value is 4.3.how to control?

HCV treatment: Great news for your your husband to have undetectable HCV. I will not worry about the mildly elevated globulin level. You may want to repeat it in a few weeks. ...Read more

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What is the course of duration of peginterferon(interferon alfa2b) in the treatment of hepatitis b? Plz explain in detail.

What is the course of duration of peginterferon(interferon alfa2b) in the treatment of        hepatitis b? Plz explain in detail.

Hepatitis B: Interferon Alfa 2B can be used for treatment of CHRONIC hepatitis B. It is not for acute Hepatitis B which often resolves spontaneously. The dose for chronic hep B is 10 mill units subcutaneous or IM shot 3times/week for 16 weeks, or 5 mill units daily for 16 wk. get with your doctor to see if you have the chronic form of hepatitis. Good luck! ...Read more