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Doctor insights on: Peginterferon Alfa 2b

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Dr. Neigatha Graney
2 doctors shared insights

Peginterferon Alfa 2b (Overview)

Peginterferon alfa-2b is a gastroenterology drug.


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What effects does betaseron (interferon beta 1b) have on breastfeeding?

What effects does betaseron (interferon beta 1b) have on breastfeeding?

Interferon for MS?: It should be okay. No information is available regarding whether it can be passed onto an infant in mother's milk. No studies are available regarding harm in infants. Have your pediatrician monitor the progress during the health maintenance visits. ...Read more

Dr. Neigatha Graney
2 doctors shared insights

Peginterferon Alfa 2b (Overview)

Peginterferon alfa-2b is a gastroenterology drug.


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Can you tell me the difference between peginterferon alfa 2a & peginterferon alfa 2b?

Can you tell me the difference between peginterferon alfa 2a & peginterferon alfa 2b?

Drug names: Both are pegylated interferons. Peginterferon alfa 2a is made by roche branded Pegasys (peginterferon alfa 2a) and is a slightly larger molecule. Peginterferon 2B is made by schering and its dose is calculated based on body weight. The brand name is peg-intron. These drugs have similar efficacy and side effects. ...Read more

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What are the differences between immunosuppressive drugs and rituxan (rituximab)?

What are the differences between immunosuppressive drugs and rituxan (rituximab)?

Rituximab: Rituximab is one class of immunosuppresant therapy. It is an chimeric (composed of human and animal) monoclonal antibody directed against a surface marker (cd20) on your b-cells. Your b-cells naturally produce your own body's antibodies to help fight infections. There are other types of immunosuppresants which have different targets than b-cells, such as t-cells, and cytokines such as tnf-alpha. ...Read more

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What are common side effects of combination (ribavirin + interferon) treatment?

What are common side effects of combination (ribavirin + interferon) treatment?

Lots...: Fatigue, headache, rigors, fever, insomnia, irritability, depression, dizziness, impaired concentration, anxiety, emotional lability, hair loss, pruritus, dry skin , rash, nausea, anorexia , weight loss, diarrhea, vomiting, abdominal pain, anemia, injection site reaction, muscle and joint pains, shortness of breath, cough, flu-like symptoms, birth defects, chest pain, suicidal behavior to start. ...Read more

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Any side effects from rituxan (rituximab) therapy?

Any side effects from rituxan (rituximab) therapy?

Mostly infusion rxns: Rituxan is given intravenously slowly at first to look for common immediate reactions like chills, fever, shakes, itching, hives, headache all of which could be prevented or lessened by giving premedications like Benadryl (diphenhydramine) and steroids. Reactivation of hepatitis b, lowering resistance to infections, rapid destruction of tumor cells causing i'll effects to organs (tumor lysis) can also occur. ...Read more

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My husband is taking mestinon, (pyridostigmine) methotrexate, and prednisone for myasthenia gravis. Are all 3 needed?

My husband is taking mestinon, (pyridostigmine) methotrexate, and prednisone for myasthenia gravis.  Are all 3 needed?

Quite possibly: About 1/3 can see spontaneous remission, 1/3 stabilize on chronic medications, and 1/3 have progressive difficulties. In appropriate candidates, minimally invasive thoracic surgery to remove thymus (thymectomy) can possibly cure or stabilize disease or decrease amount and/or types of meds. This link may help: http://goo.Gl/3xxmd. ...Read more

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Is it safe to get a hepatitis b vaccine while on anabolic steroids? Hepatitis b vaccine anabolic steroids

Is it safe to get a hepatitis b vaccine while on anabolic steroids? Hepatitis b vaccine
anabolic steroids

Yes: The Hepatitis B Vaccine is not a live vaccine but is made from dna particles only and cannot cause infection. It is well tolerated and safe. This vaccine is given even to newborn babies (in a smaller dose) 3 doses will normally give immunity for life. There is an accelerated dosing given to those traveling into high risk zones--this dosing requires a later fourth dose. Bad disease--get protected! ...Read more

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Drug interactions Sotalol, sertraline & amiodarone ?

Drug interactions
  Sotalol, sertraline & amiodarone ?

Adverse effects: Significant QT prolongation. Symptoms need immediate evaluation may indicate torsade de pointes, eletrolyte abnormalities. Combination of multiple drugs that prolong QT interval is not advisable. needto check magnessium and potassuim levels. ...Read more

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Can retrovir (zidovudine) and stavudine (d4t, zerit) be taken together in an HIV regimen of medicine?

Can retrovir (zidovudine) and stavudine (d4t, zerit)  be taken together in an HIV regimen of medicine?

Yes: But the choice of combinations will depend upon assessment by a competent HIV specialist, measuring not only the sensitivity of the virus in a given patient, but the tolerance of that patient to the side-effects of the medicines. ...Read more

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What is isoniazid inh taken for?

What is isoniazid inh taken for?

Tuberculosis : Inh is one of drugs used to treat pulmonary tuberculosis. ...Read more

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What is the new treatment for hep c and liver cirohsis if the patient is not the right candidate for interferon.

What is the new treatment for hep c and liver cirohsis if the patient is not the right candidate for interferon.

New medicines : Many newer medications in clinical trials have treated patients very successfully with interferon- free regimens treatment in clinical trials offers access to the medicines prior to general use, and several should be approved soon. Some are called proteases and nucleotides. Once they prove to work and not cause too many side effects, the fda will review and eventually approve for general use. ...Read more

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Results: Hep C quant. : 2,802,680 HCV log10: 6.448. Reflex to genotype was unable to determine genotype even though there was sufficient HCV RNA?

Results: Hep C quant. : 2,802,680 
HCV log10: 6.448. Reflex to genotype was unable to determine genotype even though there was sufficient HCV RNA?

Hepatitis C virus: Sometimes it's not possible to determine the genotype of this virus, which thus makes the expected response to treatment more uncertain. This is a 'slippery virus' -there are 11 major genotypes (designated 1-11), and many subtypes (a, b, c, etc.) A hepatologist (GI subspecialist) or an ID doctor who works with Hep C patients can help you. You'll need an established relationship for treatment... ...Read more

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What exactly is adjuvant chemotherapy?

What exactly is adjuvant chemotherapy?

Preventative: Adjuvant therapy, is treatment given following the primary, main or initial treatment. It is usually given after surgery where all detectable disease has been removed, but where there remains a statistical risk of relapse due to occult disease In contrast neoadjuvant therapy, is given before the main treatment to reduce the size of the tumor so as to facilitate more effective surgery. ...Read more

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HC worker. 1992 Hep B vac, 2004 titer & booster. 2012 labs hep B neg. Labs done last wk; now told that Hep B test is positive?? How can this be?

HC worker. 1992 Hep B vac, 2004 titer & booster. 2012 labs hep B neg. Labs done last wk; now told that Hep B test is positive?? How can this be?

The vaccine worked: Lab tests aren't perfect and sometimes can be wrong. Or maybe the negative result was from the wrong kind of test. Vaccination makes hepatitis B surface antibody (HBsAb) positive. Tests for surface antigen (HBsAg) or core antibody (HBcAb) remain negative. Most important, you can be sure you are immune and protected by the vaccine -- so no worries. ...Read more

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Dose dalacin c 300 mg works correctly for infection ?

Dose dalacin c 300 mg works correctly for infection ?

Depends . . .: Whether any given antibiotic works depends upon whether the infection is caused by a sensitive bacteria. For instance, common cold is caused by a virus and thus won't be affected by any antibiotic. Anyway, dalacin c is a brand not sold in the states. Whether the generic Clindamycin will work "correctly" depends upon what caused your infection. Ask your doc for culture & sensitivity. ...Read more

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(28 male) hb 11.5, hct 35.9, MCH 25.3, uibc 380, serum iron 18, iron saturation 5, serum ferritin 5. Have taken oral iron drops? Any concerns?

(28 male) hb 11.5, hct 35.9, MCH 25.3, uibc 380, serum iron 18, iron saturation 5, serum ferritin 5. Have taken oral iron drops? Any concerns?

IDA - cause?: The best measure of iron deficiency anemia (ida) is serum ferritin (which is low here). The gold standard is a bone marrow biopsy (bmb), but that is rarely needed. The real question is what is the cause of the ida in a 28 year old male? Iron can help improve the iron stores and ability to produce rbcs and raise hgb. Need to find root cause. ...Read more

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What is longterm prognosis for grade 3, stage 1b, triple positive breast cancer, double mastectomy and 6 treatments of TCH with one year of herceptin, (trastuzumab)?

What is longterm prognosis for grade 3, stage 1b, triple positive breast cancer, double mastectomy and 6 treatments of TCH with one year of herceptin, (trastuzumab)?

Better now: Exact prognosis is not possible, but your oncologist should discuss your prognosis with based on population statistics, such as Adjuvant! Online, or better still, your Oncotype Dx score based on the gene profile of your cancer. ...Read more

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Can you tell me the difference between peginterferon alfa 2a & peginterferon alfa 2b?

Drug names: Both are pegylated interferons. Peginterferon alfa 2a is made by roche branded Pegasys (peginterferon alfa 2a) and is a slightly larger molecule. Peginterferon 2B is made by schering and its dose is calculated based on body weight. The brand name is peg-intron. These drugs have similar efficacy and side effects. ...Read more

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What is the definition or description of: Peginterferon alfa 2b allergy?

What is the definition or description of: Peginterferon alfa 2b allergy?

Interferon SEs: Pegylated interferon alfa-2b, or PegIntron, acts as a cytokine agent to help rid the body of certain types of infections. It was a used in Hep C treatment in the past. Side effects can include headache, fatigue, mood changes, trouble sleeping, hair loss, nausea, pain at the injection site, fever, plus other more severe effects including psychosis, liver problems, blood clots, heart trouble etc. ...Read more

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Hepatitis c injection" peg intron (peginterferon alfa 2b) a" has many side effects. How can they be decreased.?

Hepatitis c injection" peg intron (peginterferon alfa 2b) a" has many side effects. How can they be decreased.?

Tylenol (acetaminophen) / Benadryl: You can try premedicating with tylenol (acetaminophen) and benadryl. Alternate injection sites. Get plenty of rest. ...Read more

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Will I be able to drink alcohol while taking the medications ribavirin and peg intron (peginterferon alfa 2b)?

Will I be able to drink alcohol while taking the medications ribavirin and peg intron (peginterferon alfa 2b)?

Not recommended: Ribavirin must be used together with a Peg-Intron to treat chronic hepatitis C. Do not drink alcohol while taking ribavirin. Alcohol can increase the risk of damage to your liver. Hope it makes sense? ...Read more

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Is juvederm safe while taking peginterferon and ribasphere. No mor detail

I would wait to use: Usually when being treated with peg interferon and ribavirin, you become immunosuppresed (i.e. Low immune system), so any other injections like juvederm can lead to local inflammation/skin reactions, infections and confound the other symptoms that you might be experiencing while undergoing treatment. I would wait to use juvederm until you finish your treatment therapy. ...Read more

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Need info on interferon alfa-2b?

Need info on interferon alfa-2b?

Google it: Since i don't know what specific information you need, it is difficult to answer in a concise manner given the limitation of our responses. Honestly i would "google it" as there are a lot of medical and non medical topics that might help you. If you have further specific questions, i would be happy to answer. ...Read more

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Who should not take interferon alfa-2b injections?

Contraindications: See list of contraindications at: https://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=12503

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What are effects of pegasys (peginterferon alfa 2a)?

Depends: From a hepatitis c treatment standpoint, using Pegasys (peginterferon alfa 2a) in combination with Ribavirin and a protease inhibitor can have dramatic treatment effect (i.e. Lead to cure of hepatitis c depending on the stage of your liver disease). Now "side-effects" can range from "flu-like" symptoms to lab abnormalities, depression, rash, GI symptoms, anxiety/irritability, insomnia, etc. Discuss with your doctor. ...Read more

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What happens when I miss a dose of peginterferon alfa-2a ?

Report it: When you miss a dose of peg interferon, you should report it to your treating physician. If it is just one dose, chances are you may have it injected later that day or week. If it is not feasible, i think you will still need to continue on with your treatment, as one dose is unlikely to change the trend you've had. Talk to you doc, though. ...Read more

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What are the potential side effects of peginterferon alfa-2a ?

What are the potential side effects of peginterferon alfa-2a ?

Talk to your doctor!: Some of the common side effects of Pegasys (peginterferon alfa 2a) (peg-interferon alfa-2a) are fatigue, depression, headache, fever, low white cell count, muscle pain and chills. However, there are potentially more serious side effects as well. The risk of developing side effects may depend on your other health problems. You should talk to your doctor. ...Read more

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Any long term side effects from pegasys (peginterferon alfa 2a)?

Usually not: In general, once you have finished your treatment with pegasys, (peginterferon alfa 2a) side effects/symptoms that you were having during treatment slowly disappear, but can take up to 6 months and in some instances 1 year although rare. It can result in autoimmune disorders, although this is also rare. I would discuss your concerns with your treating physician for other rare long term side effects. ...Read more

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What side effects are associated with interferon alfa-2b injections?

Many; see below: Many of patients experience flu-like symptoms like fever, chills, headache, fatigue, and weakness within 1-2 hours of taking the medication. Symptoms like irregular heartbeat, chest pressure or tightness, hallucinations, irritability, insomnia, depressive mood, and suicidal thoughts may also occur. It’s important to report any of these to your doctor. ...Read more

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What are some common side effects of pegasys (peginterferon alfa 2a)?

What are some common side effects of pegasys (peginterferon alfa 2a)?

Flu-like symptoms: Although Pegasys (peginterferon alfa 2a) has been known to make psychiatric symptoms worse and cause some problems with bone marrow suppression (anemia, low white count, low platelets), the most common side effect is flu-like symptoms. ...Read more

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What are the drugs those can interact with pegasys (peginterferon alfa 2a)?

What are the drugs those can interact with pegasys (peginterferon alfa 2a)?

Many: There is a long list of drugs that may interact. The main ones are azathioprine, methadone, stavudine, telbivudine and theophylline. You should take to your doctor to make sure that your curent medicines do not interact with pegasys (peginterferon alfa 2a). ...Read more

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What is the usual procedure for preparing and injecting pegasys (peginterferon alfa 2a)?

What is the usual procedure for preparing and injecting pegasys (peginterferon alfa 2a)?

Simple Steps: Simple steps but all need to be done and it is best to have formal treating by a health care provider before starting. Basically it involves preparing the syringe and then drawing up the medication. Next you will need to find a spot on your abdomen or thigh and then inject into a pinched segment of skin. ...Read more

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Hi I'm 37 yr old and HCV + geno 3 ,should I go for interferon 2a + ribav or peginterferon 2a + ribav ,which is the best for me ,please advice.

Hi I'm 37 yr old and HCV + geno 3 ,should I go for interferon 2a + ribav or peginterferon 2a + ribav  ,which is the best for me ,please advice.

Harvoni: Well my dear your in luck. A new medication called Harvoni just came on the market. Its a combination of 2 very very effective medications (Ledipasvir-sofosbuvir). Its 1 pill a day, no interferon or ribaviron needed. The cure rate at 12 weeks is reported to be spectacular @ >94%. 12 weeks and your done. Ask your infectious disease doctor....its going to revolutionize Hep C treatment! ...Read more