Top
30
Doctor insights on: Peginterferon Alfa 2a

Share
Dr. Jeffrey Wint
18 Doctors shared insights

Peginterferon Alfa 2a (Overview)

Peginterferon alfa-2a is a gastroenterology drug.


1

1
What are the potential side effects of peginterferon alfa-2a?

What are the potential side effects of peginterferon alfa-2a?

Talk to your doctor!: Some of the common side effects of Pegasys (peginterferon alfa 2a) (peg-interferon alfa-2a) are fatigue, depression, headache, fever, low white cell count, muscle pain and chills. However, there are potentially more serious side effects as well. The risk of developing side effects may depend on your other health problems. You should talk to your doctor. ...Read more

Dr. Jeffrey Wint
18 Doctors shared insights

Peginterferon Alfa 2a (Overview)

Peginterferon alfa-2a is a gastroenterology drug.


2

2
What are effects of pegasys (peginterferon alfa 2a)?

Depends: From a hepatitis c treatment standpoint, using Pegasys (peginterferon alfa 2a) in combination with Ribavirin and a protease inhibitor can have dramatic treatment effect (i.e. Lead to cure of hepatitis c depending on the stage of your liver disease). Now "side-effects" can range from "flu-like" symptoms to lab abnormalities, depression, rash, GI symptoms, anxiety/irritability, insomnia, etc. Discuss with your doctor. ...Read more

3

3
What happens when I miss a dose of peginterferon alfa-2a?

What happens when I miss a dose of peginterferon alfa-2a?

Report it: When you miss a dose of peg interferon, you should report it to your treating physician. If it is just one dose, chances are you may have it injected later that day or week. If it is not feasible, I think you will still need to continue on with your treatment, as one dose is unlikely to change the trend you've had. Talk to you doc, though. ...Read more

4

4
What are the potential side effects of peginterferon alfa-2a?

Talk to your doctor!: Some of the common side effects of Pegasys (peginterferon alfa 2a) (peg-interferon alfa-2a) are fatigue, depression, headache, fever, low white cell count, muscle pain and chills. However, there are potentially more serious side effects as well. The risk of developing side effects may depend on your other health problems. You should talk to your doctor. ...Read more

5

5
Any long term side effects from pegasys (peginterferon alfa 2a)?

Usually not: In general, once you have finished your treatment with pegasys, (peginterferon alfa 2a) side effects/symptoms that you were having during treatment slowly disappear, but can take up to 6 months and in some instances 1 year although rare. It can result in autoimmune disorders, although this is also rare. I would discuss your concerns with your treating physician for other rare long term side effects. ...Read more

6

6
What are some common side effects of pegasys (peginterferon alfa 2a)?

What are some common side effects of pegasys (peginterferon alfa 2a)?

Flu-like symptoms: Although Pegasys (peginterferon alfa 2a) has been known to make psychiatric symptoms worse and cause some problems with bone marrow suppression (anemia, low white count, low platelets), the most common side effect is flu-like symptoms. ...Read more

7

7
What are the drugs those can interact with pegasys (peginterferon alfa 2a)?

What are the drugs those can interact with pegasys (peginterferon alfa 2a)?

Many: There is a long list of drugs that may interact. The main ones are
azathioprine, methadone, stavudine, telbivudine and theophylline. You should take to your doctor to make sure that your curent medicines do not interact with pegasys (peginterferon alfa 2a). ...Read more

8

8
Can you tell me the difference between peginterferon alfa 2a & peginterferon alfa 2b?

Can you tell me the difference between peginterferon alfa 2a & peginterferon alfa 2b?

Drug names: Both are pegylated interferons. Peginterferon alfa 2a is made by roche branded Pegasys (peginterferon alfa 2a) and is a slightly larger molecule. Peginterferon 2B is made by schering and its dose is calculated based on body weight. The brand name is peg-intron.

These drugs have similar efficacy and side effects. ...Read more

9

9
What is the usual procedure for preparing and injecting pegasys (peginterferon alfa 2a)?

What is the usual procedure for preparing and injecting pegasys (peginterferon alfa 2a)?

Simple Steps: Simple steps but all need to be done and it is best to have formal treating by a health care provider before starting. Basically it involves preparing the syringe and then drawing up the medication. Next you will need to find a spot on your abdomen or thigh and then inject into a pinched segment of skin. ...Read more

10

10
Long term after effect of pegasys (peginterferon alfa 2a) interferon?

Usually none: Most, if not all side effects usually resolve over 4-6 weeks. Rarely, some autoimmune conditions such as alopecia (loss of hair) if precipitated may not reverse. ...Read more

12

12
Infergen use after pegasys (peginterferon alfa 2a) failure appropriate?

Not really: I am assuming you are asking about hepatits c treatment. Infergen is an old type of interferon. Data suggest that Infergen has little or no benefit after Pegasys (peginterferon alfa 2a) failure. There are new oral medications. These medications (pills) along with Pegasys (peginterferon alfa 2a) and Ribavirin has very good response rate, if you are infected with type I hepatitis c virus. Response rate is doubled from previous treatment. ...Read more

14

14
What is the difference between pegasys (peginterferon alfa 2a) & peg-intron?

What is the difference between pegasys (peginterferon alfa 2a) & peg-intron?

Size of the molecule: Pegasys (peginterferon alfa 2a) is larger size and comes in solution where as pegontron comes as powder that needs to be reconstituted with saline before administration. Efficacy wise, Pegasys (peginterferon alfa 2a) may be marginally better. ...Read more

15

15
Why are some slow in seeking approval for peg-intron and pegasys (peginterferon alfa 2a)?

Why are some slow in seeking approval for peg-intron and pegasys (peginterferon alfa 2a)?

Price: It is a very expensive medication!
insurance want to make sure it is indeed indicated before paying such a pricey medication. ...Read more

16

16
What is the difference between pegasys (peginterferon alfa 2a) & pegintron in treatment of hcv?

What is the difference between pegasys (peginterferon alfa 2a) & pegintron in treatment of hcv?

Packaging...: Pegasys (peginterferon alfa 2a) and pegintron (peginterferon alfa 2b) are two drugs fda approved for treatment of chronic hepatitis c. They are slightly different in their chemical composition but studies indicate they are virtually equally effective in what they do and have very similar side effect profiles. Insurance usually drives which of the two is preferred on their formulary. ...Read more

17

17
What is the difference between pegasys (peginterferon alfa 2a) & pegintron for treatment of hcv?

What is the difference between pegasys (peginterferon alfa 2a) & pegintron for treatment of hcv?

Very little: These are both long acting forms of pegylated interferon that can be injected once a week. Cure rates using each are similar. Pegasys (peginterferon alfa 2a) has been given a slight edge in cure rates by kaiser and veteran's admin studies as well as the uspstf. Most hepatitis c drug companies that combine their new drugs with interferon and Ribavirin use pegasys (peginterferon alfa 2a). But your provider will use what he/she is used to. ...Read more

18

18
I was treated with pegintron & rebitol for HCV & my count increased from 130 to 460 at 48 th vial can I complete with pegasys (peginterferon alfa 2a)?

I was treated with pegintron & rebitol for HCV & my count increased from 130 to 460 at 48 th vial can I complete with pegasys (peginterferon alfa 2a)?

No benefit: The us preventative services task force recommends that pegintron and Pegasys (peginterferon alfa 2a) are similar enough that if someone did not achieve cure with pegintron, they should not attempt retreatment with Pegasys (peginterferon alfa 2a) since it will likely not help. Talk to your provider about new options in hepatitis c drug development and when they might be available for your genotype of hepatitis c. ...Read more

19

19
Please answer! What kind of side effects remain after the completion of HCV treatment by pegasys (peginterferon alfa 2a) + ribaverine?

Please answer! What kind of side effects remain after the completion of HCV treatment by pegasys (peginterferon alfa 2a) + ribaverine?

Hepatitis C: Generally Pegasys effect is out of your system in few weeks and Ribavirin can stay in the system for upto 6 months.
After that there should be no side effects ...Read more

20

20
Will valerian root cause react badly with peginterferon alfa 2a and ribavirin for hep c?

Will valerian root cause react badly with peginterferon alfa 2a and ribavirin for hep c?

No...: Herbal remedies e.g. Valerian root, silymarin will probably not interfere with conventional antiviral treatment of hepatitis c - no studies I'm aware of. Conversely, there are no studies taking them will do any good - so you may want to save your money. Good luck! ...Read more

22

22
What is the definition or description of: Pegasys allergy?

What is the definition or description of: Pegasys allergy?

Pegasys allergy: Pegasys (Peginterferon alfa-2a) is an immunosuppressive & antiviral medication used in the treatment of hepatitis B or C. An allergy occurs when your body’s immune system creates antibodies to a foreign substance causing a reaction that can be mild to severe. For potential adverse effects see: https://www. Drugs. Com/pegasys. Html ...Read more

23

23
What are interferon alpha-2a and pegylated interferon alfa-2a (pegasys)?

2 versions 1 drug: They are the same drug except that the pegylation makes that drug longer acting, so it can be given less often. ...Read more

24

24
In my 3rd week of 180mcg pegasys/week & 800mg ribasphere/day. Imgoing on 15 days of my period (never been more than 5) w/headache, is this normal?

In my 3rd week of 180mcg pegasys/week & 800mg ribasphere/day. Imgoing on 15 days of my period (never been more than 5) w/headache, is this normal?

Pegasys (peginterferon alfa 2a) & Ribavirin: These drugs used for hepatitis c treatment, among others, can have serious side effects. Ribavirin is associated with headaches. The prolonged menstrual bleeding can be a sign of a blood dyscrasia. It would be wise to follow up with your physician immediately. ...Read more

25

25
What do you think of the hepatitis C treatment {pegasys & rebetol}?

What do you think of the hepatitis C treatment {pegasys & rebetol}?

Not only Rx: Peg-interferon and Ribavirin are the standard treatment for hepatitis c unless you have genotype 1 where addition of a pi such as Incivek (telaprevir) can improve response rates and shorten treatment course. ...Read more

26

26
Can you tell me about the hepatitis C treatment {pegasys & rebetol}?

Can you tell me about the hepatitis C treatment {pegasys & rebetol}?

AVOID: Yes. Avoid anyone recommending such treatment in 2014. This is outdated, not very effective, and CURE is now possible in nearly 100% of the cases with the more appropriate medications available today. Please get to a Hep C treater/specialist for the best outcome. ...Read more

27

27
Methadone best alt. To narcotic painkiller to ask md for from pain due to pegasys/ribavirin treatment?

Methadone best alt. To narcotic painkiller to ask md for from pain due to pegasys/ribavirin treatment?

No: Ribavirin and pegylated interferon cause many many nasty symptoms, but pain is not a prominent one of them, and there is no need for opioids. I have treated over 1000 people who were getting this treatment, and I myself went through this treatment 7 years ago (and it was a success). No narcotics should be needed or used. If you are having severe pain, something else is causing it. ...Read more

28

28
3.5 weeks of pegasys/ribasphere tx; severe light sensitivity/pain behind both eyes, neck, shoulder&hands tingling&pain; normal symptoms or should I go to er?

3.5 weeks of pegasys/ribasphere tx; severe light sensitivity/pain behind both eyes, neck, shoulder&hands tingling&pain; normal symptoms or should I go to er?

Call your doctor: These meds may cause severe flu symptoms. But you can get other illnesses causing the same symptoms- like irritation of the lining of the brain. Call your doctor. ...Read more

29

29
Is juvederm safe while taking peginterferon and ribasphere. No mor detail

I would wait to use: Usually when being treated with peg interferon and ribavirin, you become immunosuppresed (i.e. Low immune system), so any other injections like juvederm can lead to local inflammation/skin reactions, infections and confound the other symptoms that you might be experiencing while undergoing treatment. I would wait to use juvederm until you finish your treatment therapy. ...Read more