Top
20
Doctor insights on: Pegasis Interferon

Share
1

1
What are interferon alpha-2a and pegylated interferon alfa-2a (pegasys)?

What are interferon alpha-2a and pegylated interferon alfa-2a (pegasys)?

2 versions 1 drug: They are the same drug except that the pegylation makes that drug longer acting, so it can be given less often. ...Read more

Interferon (Definition)

Interferons are a diverse group of proteins that belong to a class of glycoproteins known as cytokines. Interferons were first discovered for their ability to block viral replication within host cells. They also have been found to activate immune cells for many disease processes. There are several classes of interferons, types i, ii and iii, depending on ...Read more


3

3
Infergen use after pegasys (peginterferon alfa 2a) failure appropriate?

Infergen use after pegasys (peginterferon alfa 2a) failure appropriate?

Not really: I am assuming you are asking about hepatits c treatment. Infergen is an old type of interferon. Data suggest that Infergen has little or no benefit after Pegasys (peginterferon alfa 2a) failure. There are new oral medications. These medications (pills) along with Pegasys (peginterferon alfa 2a) and Ribavirin has very good response rate, if you are infected with type i hepatitis c virus. Response rate is doubled from previous treatment. ...Read more

4

4
Long term after effect of pegasys (peginterferon alfa 2a) interferon?

Usually none: Most, if not all side effects usually resolve over 4-6 weeks. Rarely, some autoimmune conditions such as alopecia (loss of hair) if precipitated may not reverse. ...Read more

5

5
Whats intron a (interferon alfa 2b)?

Whats intron a (interferon alfa 2b)?

Interferon alpha: Is a treatment for chronic hepatitis c and is also occasionally used in certain types of lymphoma and leukemia. It is a manufactured protein that is derived from a real human protein. There are some very significant side effects that include severe flu-like symptoms, depression, nausea, diarrhea, headaches. ...Read more

7

7
Peg-intron / ribavirin treatment side effects?

Peg-intron / ribavirin treatment  side effects?

Many: The side effects are too many to list here but some of the more common ones (occur in >10% of patients) are fever, fatigue, headache, insomnia, depression, emotional lability, rash, nausea, diarrhea, weight loss, anemia, muscle aches, joint pains, flu-like syndrome and injection site reations. ...Read more

8

8
What is intron a (interferon alfa 2b)?

What is intron a (interferon alfa 2b)?

Interferon alfa-2b: Interferon Alpha 2b, made from recombinant dna, used in the treament of several illnesses. A poor name -- an intron is defined to be a portion that is transcribed by messenger RNA but then the corresponding portion of messenger RNA is removed by RNA splicing before translation. ...Read more

9

9
Glatiramer acetate (copaxone) vs. Interferon?

See answer below: Both are used in rrms with similar efficacy levels. Copaxone (glatiramer) does not need blood monitoring and is administered as a subcutaneous sc injection daily. Side effects include injection site reactions. Interferons need lab work monitoring, can be a weekly injection into a muscle (avonex), every other day sc (betaseron) or three times a week sc (rebif). Most commo side effects include flu-like symptoms. ...Read more

10

10
What is the difference between pegasys (peginterferon alfa 2a) & peg-intron?

What is the difference between pegasys (peginterferon alfa 2a) & peg-intron?

Size of the molecule: Pegasys (peginterferon alfa 2a) is larger size and comes in solution where as pegontron comes as powder that needs to be reconstituted with saline before administration. Efficacy wise, Pegasys (peginterferon alfa 2a) may be marginally better. ...Read more

12

12
What is the difference between pegasys (peginterferon alfa 2a) & pegintron for treatment of hcv?

What is the difference between pegasys (peginterferon alfa 2a) & pegintron for treatment of hcv?

Very little: These are both long acting forms of pegylated interferon that can be injected once a week. Cure rates using each are similar. Pegasys (peginterferon alfa 2a) has been given a slight edge in cure rates by kaiser and veteran's admin studies as well as the uspstf. Most hepatitis c drug companies that combine their new drugs with interferon and Ribavirin use pegasys (peginterferon alfa 2a). But your provider will use what he/she is used to. ...Read more

13

13
What are effects of pegasys (peginterferon alfa 2a)?

Depends: From a hepatitis c treatment standpoint, using Pegasys (peginterferon alfa 2a) in combination with Ribavirin and a protease inhibitor can have dramatic treatment effect (i.e. Lead to cure of hepatitis c depending on the stage of your liver disease). Now "side-effects" can range from "flu-like" symptoms to lab abnormalities, depression, rash, GI symptoms, anxiety/irritability, insomnia, etc. Discuss with your doctor. ...Read more

14

14
What is the difference between pegasys (peginterferon alfa 2a) & pegintron in treatment of hcv?

What is the difference between pegasys (peginterferon alfa 2a) & pegintron in treatment of hcv?

Packaging...: Pegasys (peginterferon alfa 2a) and pegintron (peginterferon alfa 2b) are two drugs fda approved for treatment of chronic hepatitis c. They are slightly different in their chemical composition but studies indicate they are virtually equally effective in what they do and have very similar side effect profiles. Insurance usually drives which of the two is preferred on their formulary. ...Read more

15

15
Are interferon and peg-interferon different?

PEG interferone: Peg (pegylated) interferon is a long acting interferon, used to treat hepatitis b and c. Interferons are proteins released in the body in response to viral infections. Interferons are important for fighting viruses in the body, for regulating reproduction of cells, and for regulating the immune system. ...Read more

See 1 more doctor answer
17

17
What is cimzia (certolizumab pegol) injections used for?

What is cimzia (certolizumab pegol) injections used for?

Cimzia (certolizumab pegol): Certolizumab, a biological drug, very expensive, used to treat some auto-immune diseases in selected cases ...Read more

18

18
Betaseron (interferon beta 1b) adverse reactions?

Betaseron (interferon beta 1b) adverse reactions?

Multiple..: 1) depression 2) allergic reaction 3) injection site necrosis http://www.Rxlist.Com/betaseron-drug/side-effects-interactions.Htm. ...Read more

20

20
How effective are interferon alfacon-1 injections for treating hepatitis C?

How effective are interferon alfacon-1 injections for treating hepatitis C?

Not Very: The interferons are not very effective for treatment hepatitis C. Depending on the type (genotype) of hepatitis C, the cure rate ranges from about 30% to 75% at best. There are now newer medications called Direct Acting Antivirals which are much more effective and have fewer side effects than the interferon medications. ...Read more

Dr. Creighton Wright
22 doctors shared insights

Pegasys (Definition)

Pegasys is an antiparasite agent which is a kind ...Read more