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Doctor insights on: Pdca Deming

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Read about a LPR5 gene mutation family in science magazine,does new drug LP33401 increase bone width too or juz BMD in the mice experiment?

Read about a LPR5 gene mutation family in science magazine,does new drug LP33401 increase bone width too or juz BMD in the mice experiment?

Interesting question: When I searched for lp40331, I found it to be the part no. for a John Deere T-shirt. The leprosy susceptibility genetic loci are fascinating, however. Armauer Hanson discovered Mycobacterium leprae in Bergen, Norway in 1873. Genetic susceptibility to leprosy was long suspected by epidemiologists, and now confirmed, explaining why many family or tribe members are resistant. See OMIM.org %609888 ...Read more

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New Lancet article: Obesity in middle age lowers Alzheimer's risk by a third. New Neurology: Obesity in middle age increases risk fourfold. What gives?

New Lancet article: Obesity in middle age lowers Alzheimer's risk by a third. New Neurology: Obesity in middle age increases risk fourfold. What gives?

Haven't seen either: Article are written many ways and you need to see the article to clarify it. They may have looked at different groups, may have assumes the wrong information, put in misinformation, used different statistical models etc. An in depth analysis may explain this ...Read more

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Any dr read this destroying the myth about testosterone replacement and prostate cancer by abraham morgentaler, md, facs introduction by william fa?

Any  dr read  this destroying the myth about testosterone replacement and prostate cancer
by abraham morgentaler, md, facs introduction by william fa?

Yes: Great book. Morgantaler is the doc when it comes to testosterone. When it comes to testosterone adn prostate cancer all is not what it seems. This is not standard but have a look here http://1.Usa.Gov/n7ggvn ...Read more

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Brain mri-white spots/migraines. Told this is abnormal for 39 y/o. Dad & grandma-early onset dementia (50s). Do white spots = dementia in my future?

Brain mri-white spots/migraines. Told this is abnormal for 39 y/o. Dad & grandma-early onset dementia (50s). Do white spots = dementia in my future?

...hold on cowgirl!!: I've seen lots of scanned images with "white spots" that turned out to be artifact rather than tissue pathology...Similar to having a dirty lens on your microscope! there are some genetic markers for certain types of dementias that would be much more useful to you...And all it takes is a swab of the buccal mucosa inside your mouth, and, of course, a little money! seek more opinions on "white dots". ...Read more

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Non-native French speaker here: reading my 5 month-old books in French won't negatively affect or slow her language development will it?

Non-native French speaker here: reading my 5 month-old books in French won't negatively affect or slow her language development will it?

Bilingualism does: not cause receptive or expressive delays. A typical child may learn one language more rapidly & may mix words from each. Age 0-5 is optimal for learning a language's phonemes, or smallest units of sound, so (s)he can learn incorrect phonemes with prolonged exposure. Mixed/expressive language disorder, Autistic Spectrum Disorder or Global Developmental Delays require that one language be taught. ...Read more

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Has anyone with atherosclerosis dissolved the plaque with meds, herbs, foods, etc.?

Has anyone with atherosclerosis dissolved the plaque with meds, herbs, foods, etc.?

Vegan diet: Medications such as statins generally stabilize the plaque which decreases chances of plaque rupture and heart attack. In smaller studies they have been shown to decrease the plaque size by very small amounts. A vegan diet low in fat and concentrated sugars probably gives the best chance of reducing plaque burden (google dr. Easselstyn for more info). ...Read more

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Any truth about vitamin K2 for reversing arterial calcification?

Any truth about vitamin K2 for reversing  arterial calcification?

Adjunct only : I think it is unfounded. Calcification isn't even the real problem in vascular disease, and vitamin k is simply a cofactor for the synthesis of the amino acid that often binds calcium. It set off my Bad Science detector. You are welcome to try it. It do 't spend too much money. ...Read more

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How does imatinib stop the signaling pathway of mutated kit in patients with gist?

How does imatinib stop the signaling pathway of mutated kit in patients with gist?

Inhibits enzyme: The drug fits precisely into a "pocket" in the enzyme encoded by the mutant gene, blocking the enzyme's function. ...Read more

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Fertility: thoughts on frenchscientists discoving link btw use of ovarian stim drugs to a 2.6 fold increase in acute lymphoma inchildren. Chlomid ok?

Fertility: thoughts on frenchscientists discoving link btw use of ovarian stim drugs to a 2.6 fold increase in acute lymphoma inchildren. Chlomid ok?

Clomid (clomiphene) risk: As with everything in medicine, time will tell , more research, etc also, if Clomid (clomiphene) is the way a couple can have a baby the benefit versus risk of other alternatives must be considered as well as costs. Clomid (clomiphene) is one of the most affordable means to stimulate ovulation. ...Read more

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21days in icu forsepsis, parkinson, prostate & kidney disease.E-coli in urine.Now urine shows same result-2 high sensitive drugs become resistant. Help.

21days in icu forsepsis, parkinson, prostate & kidney disease.E-coli in urine.Now urine shows same result-2 high sensitive drugs become resistant. Help.

Advanced question: If resistance is seen with 2 classes of antibiotic drugs, an alternate antibiotic which e coli is sensitive to, will be chosen and the source of the infection- likely a chronic foley catheter- will be removed. You ICU team of doctors is the most appropriate group to ask this question, specifically the id specialist (if there is one in your institution). ...Read more

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What is: "r/o atypical Nevus" in doctor's note?

What is: "r/o atypical Nevus" in doctor's note?

Biopsy: An atypical Nevus is suspicious for malignancy. Therefore a biopsy is often done to establish a histopathological diagnosis and treatment plan. ...Read more

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Cancer cell loves sugar.R fruits not suitable as cancer patients' diet? Read sum books tat veggie n fruit diet can inhibit cancer cell.Is tat correc?

Cancer cell loves sugar.R  fruits not suitable as cancer patients' diet? Read sum books tat veggie n fruit diet can inhibit cancer cell.Is tat correc?

Not effective: Cancer cells survive by outcompeting your normal cells. They certainly thrive on sugar, but all cells do. If you were to limit sugar, to starve out cancer, you would starve out every other cell as well. Veggie and fruit diets have health benefits but no proven anti-cancer benefits. ...Read more

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Please explain how warfarin contributes to arterial calcification, despite great lipid profile, in patient who has taken drug for 27 years.

Please explain how warfarin contributes to arterial calcification, despite great lipid profile, in patient who has taken drug for 27 years.

Some articles: I hope these studies help: http://goo.Gl/vnjyg http://goo.Gl/xwwh3 http://goo.Gl/yymu8 there are others, but i hope these help. Would be difficult to explain in this limited space. ...Read more

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U/S 2day shows 1xkidney angiomyolipoma & 2xSmall GBpolyps (<4mm). Same U/S in March15 (I was 6 mos pg at time) no mention of these? R these new? Why?

U/S 2day shows 1xkidney angiomyolipoma & 2xSmall GBpolyps (<4mm). Same U/S in March15 (I was 6 mos pg at time) no mention of these? R these new? Why?

Yes: Angiomyolipoma is a fatty tumor benign in nature. A cyst is also benign and can arise as a new condition therefore may have not been seen on prior ultrasound six months earlier. These conditions need to be followed on periodic basis ...Read more

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