Doctor insights on:
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Pneumococcal vaccine prevents infection with the pneumococcus bacteria. Infection with this bacteria can make children very sick. It causes blood infections, pneumonia, and meningitis, mostly in young children. Although pneumococcal meningitis is relatively rare (less than 1 case per 100,000 people each year), it is fatal in about 1 of 10 cases in children. Pneumococcal meningitis can also lead to other health problems, including deafness and brain damage. Before routine use of pneumococcal conjugate vaccine, pneumococcal infections caused: over 700 cases of meningitis, 13000 blood infections, about 5 million ear infections, and about 200 deaths annually in the United States in children under five. In studies, most reactions after PCV13 were mild. They were similar to reactions reported after PCV7, which has been in use since 2000. Reported reactions varied by dose and age, but on average: About half of children were drowsy after the shot, had a temporary loss of appetite, or had redness or tenderness where the shot was given. About 1 out of 3 had swelling where the shot was given. About 1 out of 3 had a mild fever, and about 1 in 20 had a ...Read more
Chemo for --- ibc marginally successful. Then mastectomy, 7 lymph nodes positive. Now the surgeon wants rad, onc wants different chemo. Help!
Yes for rad: Definitely you should get an adjuvant radiation therapy following mastectomy. As per- chemo- if you get chemo first before surgery and unfortunately the response is only marginal- that indicates that your cancer is likely is resistant to chemo.So, adding more chemo post mastetcomy doubtfully will give you any benefit. Is this er+ or er-? If this is er+- then you should get aromatase inhibitor. ...Read more
49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?
Yes: If a 2b lesion has been completely resected with a lobectomy and there is no problem 6 months post surgery the best approach is for careful follow up. Adjuvant radiation for this stage of disease has shown no survival benefit and adjuvant chemo if initiated following surgery has only shown a 5% improvement in survival. ...Read more
Survival chances. Wife 4.2 CM stage 2B bc. Micrometastis one node one with .3mm. In chemo then rads. Chose double mastectomy. Her2+ estrogen and prog+?
Moderate: Some good factors: only 1 node - and with micromet , er+ pr+. Bad features: moderate size 4.2 cm, her2+. An aggressive tumor, but she is pursuing it aggressivelly with her treatment. She is at higher risk than average for recurrence. Fortunately, new bc drugs are being developed that may be useful if she does suffer recurrence. There are many like her who are survivors - i wish you well! ...Read moreSee 1 more doctor answer
Mult.Myeloma relapsed after treatment with velcade (bortezomib), (bortezomib) melphalan&dexamethasone. Melphalan stopped in dec, velcade (bortezomib) in april. Now takes carfilzomib& dexamethasone fever39.5. No infections.What causes fever?
Fever could be side : Effects of the chemotherapeutic agents and steroids considering there's no blood infection. Tylenol (acetaminophen) should help control the fever. Follow up with your oncologist. God bless you! http://www.Livestrong.Com/article/36171-herbs-cancer/. ...Read moreSee 1 more doctor answer
Diagnoged with cutaneous tcell lymphoma nhl.Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine.Nodules over body .?
Generally, yes: Rituxan (rituximab) is an antibody that binds the surface of B lymphocytes, which includes hairy cell leukemia. By itself it can induce remissions, but it is more effective when given in combination with other agents. Here is a link to a recent paper: http://www.ncbi.nlm.nih.gov/pubmed/25195120 ...Read more
Husband stage 4 lung adeno. Rcvd rad. To brain and foot for mets 6 rnds of avastin (bevacizumab) /chemo. Brain mets gone other tumors showed mild response what now?
Continue therapy: Response is positive thus far. Will have to wait and watch. ...Read more
Faltigue most days.
Wk1-WBC8.5(38% lymp) PLT320 Hgb14.2
Wk2-WBC5.6(51% lymp) PLT280 Hgb14.6
Wk2-WBC4.2(50% lymp) PLT217 Hgb14.2
is it leukemia?
Likely not say more: Your weekly cbc tests seem unusual but along the way, ask the doc to make a blood smear and check your cells. That would be a good start to see if you need more specific tests, like a viral test since your lymphocytes count varIes and fatigue, may indicate infection, say mononucleosis,but if the peripheral bood smear shows really bad cells, more than those seen in infections,See blood docs.ingat. ...Read more
Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?
Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read moreSee 3 more doctor answers
Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?
Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more
Is smudge cells indication of HIV? Husbands was 52. Wbc was 11.72. Rbc 4.66. Hgb 12.7 Hct 37.0. Mcv 79.4 rdw-cv 14.8. Lymp%14
Smudge cells: Smudge cells are often described as ruptured chronic lymphocytic leukemia cells appearing on the blood smears of CLL patients. HIV disease is tested either by the presence of antibodies to this virus or by PCR of HIV RNA. Should discuss this with the doctor ordering these tests. If you are concerned that your husband may have HIV you should both be tested for that and for all other STDs. Best. ...Read more
Multiple myeloma patient relapsed after Velcade , Revlimid (lenalidomide) and Carfilzomib. Any hope. Patient is 80 yrs old?
Variable: The survival rate for AML is variable. Dependes on prognostic factors ( clues for good or bad chances, ) and that would mainly include age, dna gene mutation types, type of AML (seven types) and performance status of the patient. In general the younger the patient the chances are better. In addition there is a seconday AML (after previous chemotherapy or other dieseas, ) that carry poor prognosis. ...Read more
My patient was given eox chemo with 3rd cycle of tab capicite. Can he now be given adjuvant chemo ?
Direct: Plez forgive my being direct, but that is a very technical question to be taken up with an experienced oncologist. Hrs, md. www.thepmc.org. ...Read more