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Doctor insights on: Paxil Interactions

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Dr. Krishna Kumar
618 Doctors shared insights

Paroxetine (Definition)

Brand name paxil, (paroxetine) it's an ssri used for treating depression, anxiety, ocd, and several other conditions. It ...Read more


Dr. Mohammad Ashori Dr. Ashori
Family Medicine
12 years in practice
University of California - David Geffen School of Medicine at UCLA
3

3
I'm on 40mg of Paxil (paroxetine) and 135mg once daily dose of methadone. I know there's a interaction. But how risky is it? How bad is the interaction?

I'm on 40mg of Paxil (paroxetine) and 135mg once daily dose of methadone. I know there's a interaction. But how risky is it? How bad is the interaction?

Rare: The interaction are minimal. The higher the dose of these meds the higher the risk. However, overall, you are fairly safe since we rarely see complications such as arrhythmias in real practice.

Dr. Marisa Johnson Dr. Johnson
Internal Medicine - Nephrology & Dialysis
years in practice
University of Arkansas for Medical Sciences/UAMS College of Medicine
4
Dr. William Singer Dr. Singer
Pediatrics - Neurology
47 years in practice
State University of New York Upstate Medical University
5
Dr. Bennett Machanic Dr. Machanic
Neurology
48 years in practice
Johns Hopkins University School of Medicine
6

6
My doc gave me paxil and abilify (aripiprazole), then the pharmacist said there is a major interaction and to not take them together. I see alot of ppl take these.

Lots of experts: Would have your doctor talk with the pharmacist. I think direct confrontation can help clarify issues. In my opinion, if a pharmacist has a problem with a doctor's prescription, a phone call should ensue to the doctor, not provide confusing advice to the patient.

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Dr. Matthew Smith Dr. Smith
Psychiatry
36 years in practice
New York University School of Medicine
7
Dr. Stuart Winkler Dr. Winkler
Internal Medicine - Nephrology & Dialysis
44 years in practice
UCLA School of Medicine
8
Dr. Heidi Fowler Dr. Fowler
Psychiatry
21 years in practice
Uniformed Services University of the Health Sciences F. Edward Hebert School of Medicine
9

9
Dlpa supplement interaction I would like to ask a question and I intend to consult with my psychiatrist first but would like a second opinion. I am on lamictal, paxil, lithium and Adderall for ADHD and a bipolarii. My mood disorder isn't my biggest burden

Hello,: Hello, there seems to be variable input on this issue. Phenylalanine is an essential Amino Acid which is converted into tyrosine. Tyrosine is then used to produce Dopamine and norepinephrine. Of course, both of these neurotransmitters are impacted by a number of psychotropic medications. Dpla is contraindicated with monoamine oxidase inhibitors and reportedly should not be used with atypical antipsychotics. The majority of sites recommended that d.L. Phenylalanine not be used concurrently with standard antidepressant medications. Several sites recommended that dlpa not be used with Paxil (paroxetine) or with stimulants. Use of dlpa can be associated with insomnia, headaches and increased blood pressure due to overstimulation of the central nervous system. I could not find any literature that addressed using dlpa with lithium. It should be noted that the fda does not regulate supplements and that dosages of the active ingredients are often not standardized.

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Dr. Kenneth Adler Dr. Adler
Psychiatry
45 years in practice
University of Toledo College of Medicine
10

10
What does Paxil (paroxetine) do?

What does Paxil (paroxetine) do?

SSRI: Paxil (paroxetine) is a selective seritonin reuptake inhibitor. It is used to treat a number of conditions including depression, anxiety and ocd.

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Dr. Alan Ali Dr. Ali
Psychiatry
28 years in practice
University of Arkansas for Medical Sciences/UAMS College of Medicine
11

11
What's the concern with paxil (paroxetine)?

Dr. Alan Ali Dr. Ali
7 doctors agreed:
What's the concern with paxil (paroxetine)?

Paxil (paroxetine): Most concerns stem from the black box warning of increase suicidality, although rare, and the birth defects if taken during pregnancy.

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Dr. Jeffrey Juchau Dr. Juchau
Family Medicine
29 years in practice
University of Texas Medical School at San Antonio
12

12
How many hours does Paxil (paroxetine) last?

Paxil (paroxetine): The half life of Paxil (paroxetine) is 21 hours, meaning half of the drug is gone from your system in that time. It generally takes 6 half life's for a drug to be completely gone from York system. This would be 126 hours.

Dr. Chris Esguerra Dr. Esguerra
Psychiatry
12 years in practice
Keck School of Medicine of University of Southern California
13

13
Can you overdose on too many paxil (paroxetine)?

Can you overdose on too many paxil (paroxetine)?

Yes: Paxil/paroxetine's max dose is 50-60 mg. Any medication can cause severe harm when taken in an overdose. Paxil is no exception. Follow the directions from your physician. If in an overdose situation, call 911 and get immediate help.

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Dr. Alan Ali Dr. Ali
Psychiatry
28 years in practice
University of Arkansas for Medical Sciences/UAMS College of Medicine
14

14
What is the best time to take paxil (paroxetine)?

Dr. Alan Ali Dr. Ali
2 doctors agreed:

Paxil (paroxetine): In evening, since some sedation is expected.

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Dr. Jason Adler Dr. Adler
Pediatrics - Critical Care
20 years in practice
Tufts University School of Medicine
15

15
What are signs of overdose on paxil (paroxetine)?

Overdose paxil (paroxetine): Signs and symptoms of paroxetine (paxil) overdose include tremors, nausea, vomiting, sleepiness, dizziness, sweating, altered mental status, seizures, increased deep tendon reflexes, arrhythmias, and low blood pressure. Death is rare and has typically been described in patients taking multiple medications.

Dr. Jason Campbell Dr. Campbell
Family Medicine
12 years in practice
Texas A&M Health Science Center College of Medicine
16

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Can taking Paxil (paroxetine) make you gain weight?

Yes: Out of the ssri medications, Paxil (paroxetine) seems to be the one most common to contribute to weight gain (and this is on the fda adverse reaction list for this medication. Other ssris such as Prozac and zoloft (sertraline) do not have weight gain listed by fda as possible adverse reaction. Talk with your provider to consider alternatives if this concerns you.

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Dr. Brian Writer Dr. Writer
Psychiatry
12 years in practice
University of New England College of Osteopathic Medicine
17

17
Please describe the medication: paxil (paroxetine)?

SSRI Antidepressant: Paxil (paroxetine) is an ssri antidepressant approved for treatment of unipolar (as opposed to bipolar) depression as well as a variety of anxiety-spectrum conditions. It carries a relatively greater risk of medication interactions & is considered to be less safe for a developing fetus as compared to some other antidepressants. All antidepressants have risk of emergent suicidal thinking in young people.

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Dr. Heidi Fowler Dr. Fowler
Psychiatry
21 years in practice
Uniformed Services University of the Health Sciences F. Edward Hebert School of Medicine
18

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Is brisdelle the same thing as Paxil (paroxetine)?

Paroxetine is: Generic name and brand names include: BRISDELLE, PAXIL (paroxetine) & PEXEVA.

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Dr. Heidi Fowler Dr. Fowler
Psychiatry
21 years in practice
Uniformed Services University of the Health Sciences F. Edward Hebert School of Medicine
19

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Can Paxil (paroxetine) make me last longer in bed?

Maybe yes- maybe no: There is a possibility for longer erection as a side effect of paxil, (paroxetine) but it does not have this effect on all men.

Dr. Kenneth Adler Dr. Adler
Psychiatry
45 years in practice
University of Toledo College of Medicine
20

20
What is it like to quit using Paxil (paroxetine) cr?

Stopping Paxil (paroxetine): Stopping Paxil (paroxetine) abruptly can cause a discontinuation syndrome with multiple physical symptoms and increase chance of relapse. Suggest consulting with treating physician prior to attempting to stop medication.

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Paxil (Definition)

Paroxetine is a serotonin reuptake blocker which is a kind of ...Read more