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Doctor insights on: Paxil And Wellbutrin

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What's the differentiating side effects between Paxil and Wellbutrin?

What's the differentiating side effects between Paxil and Wellbutrin?

Serotonin vs dopamin: Paxil, a serotonin med, will have more GI side effects- nausea, cramping, Bowel changes, since it has a short half life, if not taken regularly some ppl report 'withdrawals' that feel like electric impulses on the nerves. Wellbutrin, a dopamine med, will have more central/autonomic nervous system SE like headaches, bp changes, insomnia, moodiness. ...Read more

Dr. Alan Ali
781 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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Unable to take anti-dep due to extreme sleepiness or fatigue (zoloft, paxil, (paroxetine) wellbutrin, etc.). Is this a common occurence or am I an exception?

Unable to take anti-dep due to extreme sleepiness or fatigue (zoloft, paxil, (paroxetine) wellbutrin, etc.).  Is this a common occurence or am I an exception?

Depression: Some people do not do well on anti-depressants. Consult with a clinical psychologist as you may do much better if your are in psychotherapy than simply taking meds. Also my workbook on depression is featured on the soundmindz.Org web site along with updated articles on depression treatment. Best wishes. ...Read more

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In essential thrombocytosis does the serotonin given off have an effect on depression? Also is it safe to take paxil, (paroxetine) wellbutrin, Ambien with et ?

In essential thrombocytosis does the serotonin given off have an effect on depression? Also is it safe to take paxil, (paroxetine) wellbutrin, Ambien with et ?

ET and depression: Et is not a contraindication to take anti depression medication . If your doctor thinks that you should be on ssri , from et-perspective , you should be fine it is not clear to me, however your statement regarding the serotonin and et . There is no relationship between et and serotonin. If your serum serotonin is elevated , your md should do a bit w/u to find out the cause of the elevation. ...Read more

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What's the best way to loose weight while on Paxil (paroxetine) and wellbutrin?

The same way: As you would if you were not on them. Eating sensibly, sleeping well and getting daily exercise. ...Read more

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Hello, is it true that the effect of Paxil (paroxetine) and wellbutrin both become less or insignificant by the time (work to limit time then not working in body).

It can happen with: Any antidepressant. We do not know why this happens. We also unfortunately do not have any comparative data on the antidepressants in this regard. Clinically i would say that I have seen Prozac last the longest without requiring change (unpublished data from my practice). We have two year data on Paxil (paroxetine) in this regard. When it happens, we augment or switch. Godt nytt år! ...Read more

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If you have broken sleep can you feel chronic dizzy/balance? Does Paxil (paroxetine) or wellbutrin help insomnia anxiety depression?

If you have broken sleep can you feel chronic dizzy/balance? Does Paxil (paroxetine) or wellbutrin help insomnia anxiety depression?

Anxiety/ depression: Paxil (paroxetine) (SSRI) may help with anxiety/ depression and as a result may also improve insomnia. Wellbutrin is not used for insomnia. It is used to treat atypical depression. Although it is not FDA approved for anxiety - recently it is is coming to light that it may help to reduce some anxious sxs. ...Read more

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Psychiatrist put me on [paxil cr 12.5, wellbutrin (bupropion) 150, clomipramine 50mg, laxoberon] all od. My anxiety attacks gettin worse.Any advise to stop panic plz?

Psychiatrist put me on [paxil cr 12.5, wellbutrin (bupropion) 150, clomipramine 50mg, laxoberon] all od. My anxiety attacks gettin worse.Any advise to stop panic plz?

Unusual combination: Wellbutrin is unlikely to help anxiety at all. Either Paxil (paroxetine) (p) or clomipramine (c) would be sufficient for anxiety disorder, but usually at significantly higher doses. If both are continued as doses are raised, there is increased risk of serotonin syndrome and and of side-effects from just c, as p tends to raise levels of c. Laxoberon for constipation. Talk to your doc about this. Hope this helps. ...Read more

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Which is better for borderline personality disorder n mood swings?Prozac, topamax, paxil, effexor, (venlafaxine) lexaproor wellbutrin?

Which is better for borderline personality disorder n mood swings?Prozac, topamax, paxil, effexor, (venlafaxine) lexaproor wellbutrin?

Depends: Any of those drugs may be useful under certain circumstances. It's important to recognize the drug is an adjunct to the primary treatment, which is long term psychotherapy. ...Read more

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Can paxil be taken if on wellbutrin and nortriptyline also?

Can paxil be taken if on wellbutrin and nortriptyline also?

Caution is advised: They can be taken together although caution is advised. Follow up with your prescribing physician if you experience any side-effects ( falls, weakness or any other unusual symptoms). ...Read more

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Have tried pristiq, (desvenlafaxine) wellbutrin, paxil, celexa, effexor, lexapro, etc. With lithium, haliperidol &abilify. A couple improve mood. Still anxious!thoughts?

Have tried pristiq, (desvenlafaxine) wellbutrin, paxil, celexa, effexor, lexapro, etc. With lithium, haliperidol &abilify. A couple improve mood. Still anxious!thoughts?

Many meds: You've tried many meds already, although there are some you haven't mentioned that often help anxiety: buspirone, beta-blockers, other mood stabilizers besides lithium, etc. But after a person has tried so many medications and still has symptoms, i'd suggest non-medication approaches: psychotherapy, mindfulness, relaxation training, exercise/yoga, etc. ...Read more

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My doc gave me Buspar (buspirone) since 2 months now and it's not working. Also proved antidepressants like zoloft, efexor, cymbalta, prozac, wellbutrin, paxil?

My doc gave me Buspar (buspirone) since 2 months now and it's not working. Also proved antidepressants like zoloft, efexor, cymbalta, prozac, wellbutrin, paxil?

Antidepressants: What is your question, it is confusing.Have you been all the antidepressants you mentioned or would like to try.You should consult your psychiatrist and discuss your concern. ...Read more

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10mg paxil (paroxetine). Pdoc wants me to switch to wellbutrin by starting at 75mg and taking 10mg Paxil (paroxetine) for 5 days then stop paxil (paroxetine). Need for Paxil (paroxetine) ween?

See a psychiatrist: I can only guess your medication is for depression. First of all I am clueless as to why your dose of Remeron is so low and every other night. Secondly i don't understand why you were coming off of just 10 mg of Paxil (paroxetine) which is rarely therapeutic. Thirdly, 75 mg of wellbutrin is too low as a starting dose. Find yourself a psychiatrist who will dose your meds properly with full remission from the depression as a goal. This will generally take 300 mg a day of wellbutrin.You can taper the Paxil (paroxetine) to 5 mg down from 10 and then stop it if you wish. That may help make any potential withdrawal more tolerable. Best wishes. ...Read more

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I have to cold turkey wellbutrin and Paxil (paroxetine) because i can't afford them anymore, is this going to hurt me? I'm already having zaps...

I have to cold turkey wellbutrin and Paxil (paroxetine) because i can't afford them anymore, is this going to hurt me? I'm already having zaps...

Won't damage you...: But if you are already having "zaps" or discontinuation symptoms, don't cold turkey" it. Generic Paxil (paroxetine) is on the 4 $ list of meds at target ; walmart. So you can get 30 tabs of either the 10 or the 20 mg dose for 4 bucks, or a 90 day supply for just $10. There are also other ways to get low cost meds if you do an internet search. Stopping wellbutrin (bupropion) is not usually a problem, Paxil is. ...Read more

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I take PAXIL (paroxetine) CR 37.5 MG DAILY FROM THE LAST 5 YEARS I WANT TO SWITCH TO WELLBUTRIN SR BT HOW MUCH IS ALL I WANT TO KNW ? ANY OTHER ADVICE THANK U :)

I take PAXIL (paroxetine) CR 37.5 MG DAILY FROM THE LAST 5 YEARS I WANT TO SWITCH TO WELLBUTRIN SR BT HOW MUCH IS ALL I WANT TO KNW ? 
ANY OTHER ADVICE 
THANK U :)

Need physician. : Paxil (paroxetine) has to be taper down gradually first. And u have to discuss with your psychiatrist about side effect and benefit of wellbutrin first. It's not what is equivalent dose but most important is how much you needs it and why you needs it . It is not wise to change without physician guidance. ...Read more

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Dr. Alan Ali Dr. Ali
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What do abilify, (aripiprazole) wellbutrin and Paxil do?

Dr. Alan Ali Dr. Ali
1 doctor agreed:

Combo: Together they treat depression which was not sufficiently managed with one antidepressant. ...Read more

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If im taking paxil (paroxetine) 30mg at what dose of wellbutrin to reverse sexual side effect ?

ED / R/O. LOW T: Paxil (paroxetine) at does above 20mg may decreSe libido. You should get a full exam and lab check, especially free and total testosterone , you may be going through male menopause (ANDROPAUSE ). If it is due to the Paxil (paroxetine) you can taper down or transistion to CYMBALTA which has less side effects . Also I recommend the Anxiety& Phobia Workbook for great overview of treatment strategies. ...Read more

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What to do if i developed a tolerance to Paxil (paroxetine) and the doctor changed me to wellbutrin.?

Follow your doctor : Your physician had a reason for recommending the change. Ask him/her for the reason, try the wellbutrin (bupropion) and if it doesn't help in a couple of weeks, ask to try something else. ...Read more

Dr. Krishna Kumar
617 doctors shared insights

Paroxetine (Definition)

Brand name paxil, (paroxetine) it's an ssri used for treating depression, anxiety, ocd, and several other conditions. It ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more