Doctor insights on:
Pauci Immune Vasculitis
See details: It is a form of vasculitis effecting medium sized arteries and associated with a positive canca blood test. It usually begins as chronic sinusitis but with time can effect many other organ systems including eyes, heart, kidneys, joints, lungs and the nervous system. There are very effective treatments available. ...Read more
Not typically and : They can be seen in various scenarios. ...Read more
Generally yes.: Autoimmune disorders deregulate the immune system and may even compromise it. The medications used to manage these disorders suppress the immune system predictably. ...Read more
Yes: They represent any abnormal immune response and often therefore will suppress the normal immune response. ...Read more
SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more
No: No fibromyalgia is not an autoimmune disease. Fibromyalgia is a syndrome and not a disease. This means it is a collection of symptoms. The hallmark of fibromyalgia is chronic widespread pain. It is felt to be the result of overactive nerves. There appears to be abnormal processing of pain in the central nervous system. (the brain and the spinal cord). ...Read moreSee 2 more doctor answers
Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read moreSee 1 more doctor answer
Clear definition: Immune deficiency means that there is a defect in the immune system, and the person is more susceptible to have infectious diseases and cancer. There are ways to help be free of infections. Autoimmunity is a disorder in which the immune system attacks one or more of our own organs, due to a defect of regulation/tolerance. Treatment is with medications to suppress the immune responses. ...Read moreSee 1 more doctor answer
Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more
Does infectious disease specialist treat or study systemic scleroderma. Undifferentied diffuse connective tissue disease,raynauds?
No: these are generally dealt with by rheumatologists. Good luck. ...Read more
The kidney: Lupus nephritis by definition is the kidney and this is the system affected. However, SLE rarely just affects the kidney alone and other systems including skin, joints, heart, lungs, nervous system, an also be affected by lupus. Lupus nephritis requires major treatment by a specialist. ...Read more
Seizures mouth ulcers hepatocellular disease low blood count anticardiolipin antibodies 1:80 speckled ANA osteoarthritis spine Si joints LUPUS maybe?
I already have GPA vasculitis, what are my chances of getting any other type of vasculitis even when I'm immune suppressed? Thanks
Infections chances+: Immunosuppression for vasculitis can put you at risk for infections , but adifferent vasculitis condition developing from immunosuppression is not there though coexisting another vasculitic condition if there can surface anytime Immunosuppression also predispose to cancers while on them for a long period , becasue of viral infections while immunosuppressed cause changes in the structure of cells ...Read more
I'm a vasculitis patient and have been immune suppressed now for 8 years, i'm worried about cancer, and recently been having a lot of sym of ovary can?
Worry isn't helpful: I see that you are on Cyclophosphamide and this matches your vasculitis history. Despite 'pop' wisdom, Cyclophosphamide doesn't cause cancer by suppressing your immune toxicity, but by direct damage to genes. The usual cancers are bladder and acute myelogenous leukemia. Hopefully you get regular pelvic exams with palpation of your ovaries; this is the best screen for ovarian ca. ...Read more
Dr says I've immune low platelets & vasculitis. 28f lifelong martial artist+runner. If I'm careful, can I still bleed? Are they as serious as I read?
How low?: Mild immune thrombocytopenia is basically harmless, a disease of the lab tests. If your platelets are around 50,000 or below, I'd get a couple of opinions. I'd also insist on a more specific diagnosis that "vasculitis". Do you perhaps have lupus? How has the workup proceeded? I'm very glad you're exercising and if impact sports become a problem, consider swimming (my sport). ...Read more
Vasculitis on my skin, unknown cause, SGOT 43 on blood test everything else is normal hepatitis abc and auto immune negative, what could be going on?
Hard to cure: Vasculitis or arteritis can be associated with many conditions. If collagen vascular, like lupus, medication may control, if giant cell arteritis, such as temporal arteritis, steroids might totally reverse. In most other cases, chronic treatment with medication over years is necessary. Since most of these disorders are autoimmune, success may be on the horizon in some cases. ...Read more
Vasculitis is a: Very complicated illness. It can be mild or extremely severe and yes patients can die from vascuilitis. When vasculitis (or inflammation of blood vessels) affects organs such as the kidneys and/or brain, and bowel for example severe illness can occur and death can follow. There is treatment and you need to work closely with your doctors to prevent end organ damage and potentially death. ...Read moreSee 1 more doctor answer
Why ask why?: Vasculitis is defined by the presence of inflammatory white blood cells in blood vessel walls with reactive damage to mural structures. This can lead to bleeding and ischemia/necrosis downstream of the vessel. Affected vessels vary in size, type, and location in association with the specific type of vasculitis. There are many different types. The exact mechanisms underlying them are unknown. ...Read moreSee 1 more doctor answer
Blood vessel disease: Vasculitis refers to inflammation of blood vessels and can refer to capillaries, veins and all sizes of arteries. It can range from minor/moderate to severe and life threatening. There are many causes and this is a disorder Rheumatlologists are trained to diagnose and treat. ...Read more
Many: There are many tests for vasculitis that should be done. Discuss this with your doctor as the list can be very long. This is because there are so many different causes for vasculitis, ranging from infection, medications, auto inflammatory conditions, cancer and several other causes. Get it checked out. ...Read more
Many Causes: Vasculitis is inflammation of blood vessels. It can show signs in the skin. But it may also be internal and affect many organs. There are a wide range of causes and they should be evaluated promptly. In general, it can be caused by infection, medications, auto inflammatory conditions, cancer, as well as many others. If it is serious, it can lead to death. Get is checked out. ...Read more
Vasculitis: Vasculitis is an inflammation of the blood vessels and both arteries and the veins can be affected. The inflammation is caused by a type of white blood cell that sticks to the blood vessel, creating a cascade of inflammation (and destruction). There are many types of vasculitis: only some have been linked to an initial infectious component (kawasaki's) but none have been found to be catchy. ...Read moreSee 1 more doctor answer
Disease or Syndrome?: Wegener's granulomatosis (wg), more recently granulomatosis with polyangiitis (wegener's) (gpa), is an incurable form of vasculitis (inflammation of blood vessels) that affects the nose, lungs, kidneys, and other organs. Due to its end-organ damage, it is life-threatening and requires long-term immunosuppression. five-year survival is up to 87%, with some of the mortality due to toxicity of rx. ...Read more
Maybe??: It is used to treat intermittent claudication resulting from obstructed arteries in the limbs. Pentoxifylline improves blood flow through peripheral blood vessels and therefore helps with blood circulation in the arms and legs (e.g. Intermittent claudication). It does not treat vasculitis, per se! additional meds in a rheumatology war chest are needed! ...Read moreSee 1 more doctor answer
Serious illness: Wegner's granulomatous angiitis is caused by antibodies against a particular protein in neutrophils. Once uniformly fatal, it is now usually managed with strong medications by specialists. The eyes, ears, throat, lungs and kidneys are the usual targets. Wegener's greatness as a physician is tarnished by his having served the third reich, though not in the death camps; some avoid his name. ...Read more