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Doctor insights on: Pathophysiology Of Ventricular Septal Defect

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Is ventricular or atrial septal defect hereditary?

Is ventricular or atrial septal defect hereditary?

Most cases no: The chances of being born with a heart defect are approximately 8 per every thousand deliveries (a little under 1%). Most babies born with a heart defect (asd, vsd or any of a multitude of others) have no family members with heart disease. Now, when there is a first line family member with a heart defect the chances increase to about 2-3%, so there may be some genetic component. ...Read more

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Dr. Barton Cook
119 doctors shared insights

Ventricular Septal Defect (Definition)

A heart defect due to an abnormal connection between the lower chambers ...Read more


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What is different between PFO and ostium secundum atrial septal defect?

What is different between PFO and ostium secundum atrial septal defect?

Size & Location: A pfo is the persistence of a normal fetal communication between the top two chambers of the heart. A secundum ASD is an abnormal hole in the atrial septum. They vary in size though, so treatments vary. ...Read more

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What are causes of atrioventricular septal defect?

What are causes of atrioventricular septal defect?

Unknown: The heart is a very complex organ. We still do not fully understand how the normal heart develops in the fetus. We understand even less about what causes the heart to develop abnormally. It is likely that there are multiple genetic and environmental factors that contribute to abnormal cardiac development. ...Read more

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What is a secundum atrial septal defect?

What is a secundum atrial septal defect?

ASD: An atrial septal defect is a common congenital geart defect. It is a hole in the atrial septum - the wall between the left and right atrium. This lets blood flow from the left into right atrium (usually). If not caught at an early age, it results in excessive blood to right side of heart and lungs. Fixed with surgery (sutyred closed) or with a umbrella like device via cath. ...Read more

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Are atrial septal defects or atrial septal aneurysms ever the result of infection?

Are atrial septal defects or atrial septal aneurysms ever the result of infection?

Yes but very rarely: It is possible to have an infection in the heart which weakens the atrial septum (causing an aneurysm) or even creates a complete holes (atrial septal defects). This is a very rare finding though and the illness that caused it is generally quite severe. ASDs and atrial septal aneurysms are very common though and most just occur during fetal (i.e. baby) development . ...Read more

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Could ventricular septal defect cause diastolic murmur?

Could ventricular septal defect cause diastolic murmur?

Two ways: A large vsd with increased pulmonary blood flow may cause a diastolic flow rumble caused by a large amount of flow coming back from the lungs across the mitral valve into the left ventricle. Perimembranous and supracristal vsds can cause aortic valve deformation, and subsequent development of a diastolic murmur of aortic valve insufficiency. ...Read more

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What is meaning of a congenital heart defect in baby, especially the atrial septal defect?

Unfinished formation: The heart develops originally from a long tube that folds on itself in the embryo & forms the main chambers & features. The walls between the chambers are outgrowths that come together. If the walls did not completely form a gap will exist.In the upper chamber if a gap is left the atrial septal defect is "unfinished formation". ...Read more

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Will an interventricular septal defect automatically cause overriding of the aorta?

Will an interventricular septal defect automatically cause overriding of the aorta?

No.: There are many different types of ventricular septal defects (vsd). The only one associated with an overriding aorta is in the syndrome of tetrology of fallot. ...Read more

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What are the symptoms of atrial septal defect?

What are the symptoms of atrial septal defect?

Shortness of breath.: Many asds are asymptomatic, but when patients have symptoms, it's usually shortness of breath and exercise intolerance. If the ASD has been present for many years, it may cause an abnormal heart rhythm as well as lung injury. ...Read more

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What does hypokinesia of intraventricular septum apical.Concentric remodeling of the left ventricle w/segmental wall motion abnormality mean?

What does hypokinesia of intraventricular septum apical.Concentric remodeling of the left ventricle w/segmental wall motion abnormality mean?

Consequences: Description is very typical reflection for consequences of long term uncontrolled high cholesterol and blood pressure. I also guess that you might have had heart attack in past. (silent infarct?). Practically this mean that your heart is no longer as efficient pumping blood through your body as it used to be. You definitely need to be under care and see your doctor regularly to avoid worsening. ...Read more

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Hello doctors, can ventricular septal defect cause diastolic murmur?

Hello doctors, can ventricular septal defect cause diastolic murmur?

Not typical: The classic VSD physical finding is of course a holosystolic murmur. However, if the VSD is subarterial or supracristal, it can distort the aortic valve, sometimes causing leaflet prolapse. If this results in significant aortic insufficiency, there will be an associated diastolic murmur (with the insufficiency representing an indication for surgical repair). ...Read more

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Is pulmonary hypertension always present in atrial septal defect?

Is pulmonary hypertension always present in atrial septal defect?

No: People with asds do not always have pulmonary hypertension. An untreated ASD can potentially lead to pulmonary hypertension over a long period of time. But it's not always present. ...Read more

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What exactly is ventricular septal defect?

What exactly is ventricular septal defect?

A hole in the heart: A ventricular septal defect is one of the most common forms of congenital heart disease, and it consists of a hole in the muscular septum that separates the right and left ventricles (lower pumping chambers). The size and location of the hole determines whether or not surgery is necessary to fix the defect. In many instances, a vsd may spontaneously close without the need for an operation. ...Read more

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Can ventricular septal defect cause diastolic or systolic murmur?

Can ventricular septal defect cause diastolic or systolic murmur?

Yes: Almost all vsd's cause a syhstolic murmur. Larger defects with a lot of flow across them cause a diastolic murmur from increased flow across the mitral valve. ...Read more

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Does a ?Ventricular septal defect cause a diastolic murmur?

Does a ?Ventricular septal defect cause a diastolic murmur?

Holosystolic: Classically, a vsd results in increased blood flow from left to right ventricle due to pressure differences and results in a holosystolic murmur. Several situations where a diastolic murmur may be heard is 1) large vsd results in aortic cusp sucking into vsd and aortic regurg, 2) very large defect with so much flow to lungs and back to left side with diastolic rumble through mitral valve. ...Read more

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Why is atrioventricular septal defect common? With down's syndrome?

Chromosomal abnormal: The association of atrial septal defect with Down Syndrome is part of the constellation of body abnormalities that characterize it. ...Read more

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