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Doctor insights on: Pathophysiology Of Systemic Lupus Erythematosus

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Systemic lupus erythematosus--what is sle?

Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more


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Is there a cure for systemic lupus erythematosus (sle)?

SLE treatment: Systemic lupus erythematosus (sle) is a long-term autoimmune disorder that may affect the skin, joints, kidneys, brain, and other organs. There is no cure for sle. The goal of treatment is to control symptoms. ...Read more

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What are some alternative therapies for sle (systemic lupus erythematosus)?

What are some alternative therapies for sle (systemic lupus erythematosus)?

None: Diet and omega 3 fatty acids may help but there are no specific vitamin or herbal supplements for sle. Avoiding sugar and dairy is helpful for some people. Omega three fatty acids along with vitamin c and b complex may reduce symptoms. ...Read more

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What are the tests for systemic lupus erythematosus?

What are the tests for systemic lupus erythematosus?

Positive ANA and...: Positive ANA and a positive double stranded dna antibody titer of significance. This coupled with clinical criteria is the least required for diagnosis. ...Read more

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What is 'systemic lupus erythematosus' in clear tems?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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What are the symptoms of systemic lupus erythematosus?

What are the symptoms of systemic lupus erythematosus?

Many: People with lupus may have joint pain, skin rashes, chest pain, heart probelms, hair loss, fingers changing color in the cold, rash in the sunshine, neuro-psychologic problems. These are only soemof the symtpoms peopel can have. They can also have none of these. Your physician will evaluate all of these, get labs tests and imaging. ...Read more

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What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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Docs can you explain what is 'systemic lupus erythematosus' in clear details?

Docs can you explain what is 'systemic lupus erythematosus' in clear details?

An auto immune disea: Systemic lupus is a auto immune disease that can affect any part of the body.The immune system of the patient attacks its own body cells and tissues, and that causes inflammation and damage to the tissues it most often affecrs heart, skin.Joints, blood vessels, lungs, kidneys , liver and nervous system the incidence of sle is 9 times in women than men. ...Read more

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
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Is systemic lupus erythematosus a kind of cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Is systemic lupus erythematosus a kind of cancer?

No : It is an autoimmune disorder that can affect multiple organs. It is not cancer. ...Read more

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How can one cure systemic lupus erythematosus?

How can one cure systemic lupus erythematosus?

No cure but ...: Lupus cannot be cured but the symptoms can often be controlled. In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Lupus can be mild. Many lupus patients have non-life threatening disease. Lupus can be severe. Kidney or brain involvement portends a worse prognosis. ...Read more

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What do you recommend for systemic lupus erythematosus?

See rheumatologist: It is critical to see a rheumatologist, who can determine if it is lupus, if it actually compromises your health, what body systems are affected and if treatment is needed, to tailor the treatment to the risks they present. ...Read more

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What is the definition or description of: systemic lupus erythematosus?

SLE: Lupus erythematosus is a name given to a collection of autoimmune diseases, in which the human immune system becomes hyperactive and attacks normal, healthy tissues.Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. ...Read more

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What is the definition or description of: systemic lupus erythematosus diagnostic panel?

What is the definition or description of: systemic lupus erythematosus diagnostic panel?

Labs for a + ANA: The antinuclear antibody test (ANA) is the initial screening test for lupus, but since it produces a lot of false positives, follow up testing for other auto antibodies is needed. The other tests in the panel are usually more specific for lupus, but less sensitive. Panels sometimes produce dubious results, so any positive test has to be taken in context. ...Read more

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How much should people with systemic lupus erythematosus pay extra for the insurance in usa?

None: The reason that insurance exists is to spread the risk of any single person having any disease is divided among many healthy people with no disease.Our current system is prejudiced against anybody with a "pre-existing" illness such as yours and makes you pay extra.Makes getting insurance(or keeping it ) tough.It is a lose-lose;dr and patient, win for insurance company.My gripe with aca. ...Read more

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How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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Can active systemic lupus erythematosus be caused by prescription medication? Need expert opinions!

Drug-induced lupus: Yes, some prescription medications can definitely cause drug-induced lupus which often will resolve after the drug is stopped. Many of the drugs that can cause lupus do NOT cause lupus in the majority of people treated with them. There may be genetic susceptibility to drug-induced lupus and/or the right trigger. Many possible meds. Best way is to be evaluated by a board certified rheumatologist ...Read more

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Why is the butterfly rash in systemic lupus erythematosus?

Why is the butterfly rash in systemic lupus erythematosus?

Thin skin: Thin area around the nose/cheeks is very sensitive to sun and the first to show sle signs. ...Read more

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
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Is systemic lupus erythematosus a kind of cancer disease, and is it fatal?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Is systemic lupus erythematosus a kind of cancer disease, and is it fatal?

Not a cancer: Sle is an autoimmune disease that can affects multiple organ including kidney, brain, joints, skin, blood, eyes etc. It is not cancer. Yes, it can be very debilitating and lethal if not treated properly. You need to see a rheumatologist and discuss in detail with your md. ...Read more

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What can I use for systemic lupus erythematosus symptoms if I don't have a new doctor yet?

Many but need doctor: The first thing to do is define your lupus, everyone with lupus is different.You need to contact your physician - see a rheumatologist, define your lupus and then you decide on your treatment. Not everyone with lupus needs meds, but you need good health habits - no smoking, exercise, etc defining your type of lupus will clarify the best medications for you to take. ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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Is the cognitive dysfunction that results from systemic lupus erythematosus typically permanent?

It depends: Lupus can cause both reversible and irreversible changes to the nervous system, and these can affect personality, memory, and other basic aspects of patients' lives. That said, simply being sick can aggravate depression, sleep deprivation, etc. Controlling pain and other disruptive elements of the disease, can improve quality of life and help people be more who they would like to be. ...Read more

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Dr. John Chiu Dr. Chiu
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Prednisone is most likely to be indicated in the management of systemic lupus erythematosus due to what?

Dr. John Chiu Dr. Chiu
2 doctors agreed:
Prednisone is most likely to be indicated in the management of systemic lupus erythematosus due to what?

Antiinflammatory: Prednisone suppresses inflammation and thus it is intended to control the inflammation resulting from many diseases including lupus and rheumatoid arthritis. It is not a cure or specific for any disease , just a temporary solution. Long term high-dose prednisone can lead to many serious side effects. ...Read more

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Can systemic lupus erythematosus cause swelling in one hand?

Can systemic lupus erythematosus cause swelling in one hand?

Yes: A common symptom of sle is arthritis or joint pain and swelling which can involve just one hand. Usually there will be other symptoms as well such malar rash (red rash over the cheeks), increased sensitivity to sun, possibly hair loss and rash on the body, hands or knuckles or scalp. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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What are the risks of getting your wisdom teeth extracted with systemic lupus erythematosus?

Depends: If you have been on steroids recently for flare ups of sle, it could lead to post operative complications. Also, there is always a chance that there may be a latent cardiac problem that will only become apparent when you are under stress, like during a surgery. I would see and oral surgeon, and have him/her work with your physician to manage your case safely. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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Is lupus erythematosus infectious?

No: Is a immune based disease does not recognize self and attacks multiple organs. ...Read more

Dr. John Chiu Dr. Chiu
2 doctors agreed:
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Can I donate my eggs if I have lupus erythematosus?

Dr. John Chiu Dr. Chiu
2 doctors agreed:
Can I donate my eggs if I have lupus erythematosus?

Probably not: Since your genes may well render the baby at a higher risk of developing an autoimmune disease, I'd prefer that you don't. However it would be a different matter if you decide to have a child of your own due to your own needs but your eggs would not be ideal as donor eggs. I am not a genetic counsellor but why take the risk? ...Read more

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What is worse lupus erythematosus or polymorthic light eruption?

Lupus: Lupus can be associated with internal problems including problems with the kidneys, sores in the mouth, hair loss and other issues. Pmle involves the skin only and resolves relatively easily with topical steroid use and can be controlled with sunscreen use. Lupus can progress over time and should be monitored closely by a physician for signs of progression. ...Read more

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What is difference between lupus erythematosus and polymorthic light eruption?

Autoimmune : Lupus is an autoimmune condition in which antibodies are made against your own body. Sun can trigger a flareup of rashes associated with lupus. Pmle on the otherhand is a variable rash on sun exposed areas such as the arms and chest that occurs early in the sunny season of the year. This does not have autoantibodies associated with it. These can be distinguished via blood work and a skin biopsy. ...Read more

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What is the cause of lupus erythematosus?

Autoimmune: Systemic lupus erythematosus is an auto immune illness. This means people have a immume response against themselves and their own tissues. The hallmark blood test is a positive anti-nuclear antibody or an ana. Depending on what tissue is involved results in the clinical symptoms such as rash, arthritis, kidney disease etc. The cause seems be a combination of genetic and environmental exposures. ...Read more

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Atenolol-induced lupus erythematosus http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Atenolol-induced lupus erythematosus           http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Let me explain: I read the article, this medication could induce symptoms of autoimmune disease including lupus, but lupus has no cure to date but those symptoms disappear with the treatment. That the main difference. ...Read more

Dr. Gurmukh Singh
3 doctors shared insights

Lupus (Systemic Lupus Erythematosus) (Definition)

An inflammatory disease caused by the immune system attacking one's own tissues throughout the body. ...Read more