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Doctor insights on: Pathophysiology Of Pertussis Whooping Cough

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What is the vector of pertussis (whooping cough)?

What is the vector of pertussis (whooping cough)?

Humans: Bordetella pertussis is strictly a human pathogen.

Dr. Sue Ferranti
3,573 Doctors shared insights

Cough (Definition)

The cough reflex is a protective mechanism that uses muscles in your throat and chest to expel mucous and saliva that may contain pathogens that would otherwise possibly be inhaled via aerosol or to expel pathogens infecting the throat and respiratory system. Cough benefits the host by reducing load and benefits the pathogen which may then spread via aerosol. ...Read more


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How can bordetella pertussis (whooping cough) reproduce?

How can bordetella pertussis (whooping cough) reproduce?

Sugar/water/mucous: The human respiratory system provides a luxurious collection of sugar, protein & water in the form of airway mucous. This provides ample nutrition for whooping cough & a multitude of other germs.

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How long is pertussis (whooping cough) considered contagious after symptoms begin?

How long is pertussis (whooping cough) considered contagious after symptoms begin?

Treated or not?: If pertussis is treated and you have started antibiotics you are contagious for about 5 to 7 days. If you are not treated the period extends from 3 to 6 weeks.

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How does whooping cough - bordetella pertussis - enter your body and what does it do?

How does whooping cough - bordetella pertussis - enter your body and what does it do?

Persistent cough: It is an airborne disease that you acquire from someone else and it is highly contageous. It can result with a persistent cough that may last weeks, even after treatment with antibiotics. The cough is incapacitating.

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Can you tell me how to know whether your child has pertussis (whooping cough) or bad cough?

Can you tell me how to know whether your child has pertussis (whooping cough) or bad cough?

You get tested: Unfortunately, the vaccine avoiders have increased the frequency of pertussis in the us to dangerous levels. With wide vaccine use, this disease affected as few as 2500 nationwide with rare deaths in the early 90's but is now up to 30, 000 nationwide, with more than 30 deaths/yr, most in infants. A test of the secretions in your kids nose can be assessed for evidence of the pertussis.

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Why is pertussis (whooping cough) still common in Canada but not in other developed countries?

Why is pertussis (whooping cough) still common in Canada but not in other developed countries?

Poor immunisations: Could either be because children are not getting immunized completely. It could also be because the immunity has been seen to wane in adults so until age 64 yrs they need TDap booster so they do not transmit it to children.

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I was fully vaccinated against whooping cough yet got it when I was 8. It wasn't as severe but it was positive for pertussis. Cause?

I was fully vaccinated against whooping cough yet got it when I was 8. It wasn't as severe but it was positive for pertussis. Cause?

Immunity wanes: Pertussis immunity wanes-decreases- even when fully vaccinated. Protection against pertussis in childhood is highest in the first year after 5th vaccine. Although immunity may wane, those who contract pertussis will have less severe disease. As an adult one needs at least one Dtap booster. Women need a Dtap booster with each pregnancy to protect their infants.

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What is in the pertussis (whooping cough) immunization?

What is in the pertussis (whooping cough) immunization?

TDAP: Adults have been given an additional component to the original tetanus vaccine for many years now. So it now includes tetanus, diphtheria and pertussis components in the vaccine. It is given as a one time booster vaccine when you are due for a tetanus vaccine, but also given after pregnancy or when you are caring for a newborn to protect them from pertussis.

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What can you tell me about whooping cough (pertussis)?

What can you tell me about whooping cough (pertussis)?

Respiratory tract: The germ targets the upper and lower respiratory tract. Early on there is just a runny nose and congestion, Over time it worsens, producing an outpouring of thick mucous that leads to the chronic cough.Affected infants can cough so hard they develop brain injury and or die during the process. Adults often have an intractable cough lasting 3 months or more.

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What are the initial symptoms of whooping cough (pertussis)?

What are the initial symptoms of whooping cough (pertussis)?

Pertussis: Is divided into three stages: catarrhal, paroxysmal and convalescent. The 1st stage is characterized by common cold symptoms for 1-2 weeks. The 2nd stage is marked by the characteristic cough, and the 3rd by gradual resolution over 2-3 weeks.

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How does whooping cough / pertussis enter your body and what does it do to you?

How does whooping cough / pertussis enter your body and what does it do to you?

Pertussis: Pertussis is extremely contagious and when a person inhales aerosol droplets in the air from a cough/sneeze at close range from an infected person, the chance of infection is high. This bacteria colonize the cells lining the airways and attaches to the cilia (small projections) and there is release of pertussis toxin and tracheal toxin damaging the airway leading to most of the symptoms.

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My sons cough is very bad and was wondering could this be whooping cough or pertussis?

My sons cough is very bad and was wondering could this be whooping cough or pertussis?

Would need to test: Vaccination for pertussis is included in the immunizations given at 2, 4, 6, and 15 months, with a booster at 4-6 years. How old is your son and is he up to date on his immunizations? Pertussis can be a very serious infection and outbreaks occur due to under-immunization. If his cough sounds bad or he is acting ill, take him to his doctor and mention your concerns.

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I'm wondering why are childhood cases of whooping cough (pertussis) in children on the rise?

I'm wondering why are childhood cases of whooping cough (pertussis) in children on the rise?

Deadly choice: Cases of whooping cough (pertussis) have increased in the us from ~2500 in the mid 90s to over 15000 per year due to increases in unvaccinated infants and children.This is primarily due to the public's mistrust of vaccines after some fraudulent research suggesting linkage to autism. Various celebrities have promoted this fiction. As a result more than 30 babies die/yr from whooping cough.

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Can you please lay out the initial symptoms of whooping cough, otherwise known as pertussis?

Can you please lay out the initial symptoms of whooping cough, otherwise known as pertussis?

3 phases: Phases 1 is like a common cold (7-10 days), phase 2 is the cough that would not stop and may last up to 1-2 months and phase 3 is recovery time.

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I just found out I have whooping cough "pertussis" how did I get this and how can I ease the coughing?

I just found out I have whooping cough "pertussis" how did I get this and how can I ease the coughing?

TREAT PERTUSSIS: You probably contracted it from an adult coughing in public. 'whooping cough" is an infection caused by the bacteria, bordetella pertussis. We have had several epidemics in idaho and the west coast lately. Thought of as a childhood illness it has 'made a come back' and now infects adults. The treatment is antibiotics. Prevention is the key: everyone over 19 should get a dtap shot! Cough meds help.

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Someone at my work has whooping cough (pertussis). What can I do to protect myself from contracting pertussis?

Someone at my work has whooping cough (pertussis). What can I do to protect myself from contracting pertussis?

Doctor can evaluate: The booster shot (tdap) is recommended for all adults, of all ages, to protect against pertussis. Depending on the individual situation, one's primary care doctor can advise on whether or not antibiotics are needed.

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How do I take care of someone with pertussis? What's the best way to take care of and attenuate the symptoms of someone who has whooping cough?

How do I take care of someone with pertussis? What's the best way to take care of and attenuate the symptoms of someone who has whooping cough?

Patient care: Make sure you have had immunization against whooping cough. Wear a mask when working with the patient. Offer symptomatic care in the form of fluids. Make sure the patient is gettin plenty of steam inhalation and is properly hydrated. Wash hands with soap and water after contact with patient.

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What are the symptoms of whooping cough (pertussis)? The symptoms of whopping cough are very similar to a flu, what are the main distinctions?

What are the symptoms of whooping cough (pertussis)? The symptoms of whopping cough are very similar to a flu, what are the main distinctions?

Cough: The cough one gets with whooping cough is very specific and is more paroxysmal or like a spasm. The patient coughs until there is no air left in the lungs and when they breath in it makes a "whooping" sound. With whooping cough the patient often feels well except when coughing but with the flu they will feel poorly even when not coughing, including headache, aches and chills.

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Dr. Elizabeth Wallen
223 Doctors shared insights

Whooping Cough (Definition)

A contagious bacterial disease that often causes violent, uncontrollable coughing. Difficulty ...Read more