Doctor insights on:
Pathophysiology Of Osteomalacia
Osteomalacia: Osteomalacia is abnormal bone formation leading to softening of the bones. Abnormal bowing and increased fracture risk result. It is usually, but not always, due to vit D deficiency. There are multiple causes of vit D deficiency. Diagnosis based on clinical history, blood and urine tests, and characteristic X-ray findings. Sometimes bone biopsy may be necessary.See 1 more doctor answer
Osteomalacia: No. A Dexa detects osteoporosis, or decreased amount of bone matrix. Osteomalacia is an abnormal type of bone, soft bones, abnormal building process. You can have both osteoporosis/malacia, so dexa is still done in the workup to measure the amount of bone. Vit D deficiency, GI disorders that cause malabsorption, kidney disease, liver disease, certain drugs... all are part of the differential.See 1 more doctor answer
Yes and no: Normal bone growth and mineralization require adequate calcium and phosphate. Rickets refers to deficient mineralization at growth plates, whereas osteomalacia refers to same deficiency at bony matrix. They usually occur together, however, once growth plates have fused, only osteomalacia occurs.See 1 more doctor answer
Osteomalacia: This is a bone disorder characterized by impaired bone mineralization and impaired growth usually seen in children leading to "bowed legs" and bone and muscle pain, stunted growth. Basic problem is vitamin d deficiency. There are several causes of vitamin d deficiency. Lack of sun shine being one of those!
Vit d: Vit d from sun helps absorb calcium.
Carefully: It means a softening of the articular cartilage in joint. Usually mainly knee. It may be inherited or traumatic, and you can't stop it. Protect your joint from stress as in lb/sq ". Jumping increases this a lot, even down a stair, off a tailgate etc. Jogging is repetative trauma and can take it's toll swimming is good exercise. If swollen, gives out grinds, surg clean out may help smoothen it.
Varies: It varies a lot based upon the underlying cause. Some forms may be simply from a nutritional deficiency and may have a rapid response to nutritional supplementation; some forms may be from kidney disorders and may not have a simple treatment.
In my estimation, at: Least it should be 6 months, so the bone turnover can occur. Once you have it, I believe you should be on the Vit D therapy for years and years, initially to replenish your bone stock and later to maintain it. It goes without saying the cause, if any could be identified, should be treated as well.
So if I am teenager I need calcium so does that mean I stop eat whole grain as I may suffer from osteomalacia?
Need both: Teenagers need at least1200 mg of calcium/d, which is equivalent to 4 dairy servings or a combination of dairy and supplemental pills. If you do not get an average of 30 minutes of sun exposure daily, you should also supplement Vitamin D, as 70% of people in the northern US states have been found to be deficient. Vit D is needed for bones to use calcium. Whole grains are in breads, cereals, etc
Heard conflicting advise on calcium dosage for men. What is optimum dose if I have diabetes, osteoperosis & osteomalacia but normal calcium levels?
Don't take calcium: You need to take sufficient vitamin d from sun or supplements to be in the high side of normal. This may require as much as 10, 000 units of vitamin d3 a day. Do not take calcium supplements. All healthy unprocessed food contains calcium and all the other necessary minerals like magnesium.And zinc that you need. Small doses of zinc blocks osteoclasts. Cadmium plays a role in all these problems.
I have Osteomalacia. What exercises are safe / recommended for maintaining fitness, and what should I avoid?
Better...: Talk to your PMD......he will give the best advice depending on the extent of your disease, age, other meds and disease processes.
What causes osteomalacia? I've been told I have soft bones, or osteomalacia. What does this mean, and what causes it? .
Many causes: Osteomalacia is soften of bones secondary to decreased bone matrix and precursor cartilage.Many causes include vitamin d deficiency, reduced exposure to sunlight, kidney failure, inherited tubular defects in kidneys, diseases in chlldren include cystic fibrosis, osteogenesis imperfecta, nutritional rickets etc. Osteoporosis is lack of mineralization which comes with older age. Lack of exercise, etc.
What is the best way to increase bmd, so I can do another surgery to hold my spine w/ hardware? I have osteomalacia & osteoperosis, but normal calcium
YOU SHOULD BE: Discussing that with the doc doing your surgery as that doc may have someone he or she uses to help increase you bmd, in my practice I have pts on many different meds, a good one is prolia- twice yearly subq, or I refer pts for Reclast (zoledronic acid) a once yearly IV infusion, but u need to discuss with your docs as they may ahve one they prefer.
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