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Doctor insights on: Pathophysiology Of Iron Deficiency Anemia

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What causes iron deficiency anemia?

What causes iron deficiency anemia?

Low Iron: In women of reproductive age, one of the most common causes of iron deficiency is heavy periods. There are other causes. Blood loss, acute or chronic, can cause it as well. To determine the cause, see a doctor for evaluation and appropriate testing and treatment. ...Read more

Dr. Steven Ginsberg
1,284 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more


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Why is iron deficiency anemia a microcytic anemia?

Why is iron deficiency anemia a microcytic anemia?

Decreased Hemoglobin: Red blood cells (rbcs) are essentially little bags carrying lots of hemoglobin (hb). Iron is an important constituent of the hb molecule. Low iron = low hemoglobin = less packing into rbc. Since the RBC is now filled less, a microcytic anemia results. ...Read more

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Is polychromasia typically associated with microcytic anemia (iron deficient anemia)?

Is polychromasia typically associated with microcytic  anemia (iron deficient anemia)?

Iron deficiency is: Usually hypo chromic. Polychromasia is seen in rapidly changing circumstances like hemolytic anemia. ...Read more

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What causes anemia besides iron deficiency?

What causes anemia besides iron deficiency?

Many: There are many causes for anemia (RBC), just list a few: 1) decreased production due to not enough nutrition, B12/folate/iron def, or bone marrow diseases or bone marrow suppression from drugs/radiations or due to chronic kidney disease (not enough epoietin); 2) increased destruction: intravascular or extravascular hemolysis; 3) blood loss or chronic disease/cancer or some congenital diseases. ...Read more

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How vit cyanoCObalamine deficiency causes megaloblastic anemia?

B12: You need this vitamin to synthesize DNA (T's from U's). If you can't do this, the nuclear growth can't keep up with the cytoplasm and the red cells end up bigger before they can be released. Hence "megalo-". ...Read more

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Why is iron deficiency anemia different from the other types of anemia?

Why is iron deficiency anemia different from the other types of anemia?

Iron deficiency: There are many types of anemia caused by many types of disorders. Red blood cells require iron in order to develop properly. Without iron, we do not produce adequate numbers of cells which results in anemia. Iron deficiency needs to be explained always and requires an examination and further testing. Simply replacing iron without an investigation and or examination can result in missed diseases. ...Read more

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Can hypothyroidism cause iron deficiency anemia?

Can hypothyroidism cause iron deficiency anemia?

Yes it can: Iron deficiency anemia is more common in people with hypothyroidism.Red blood cells production falls and it can not be corrected just by iron sup;ements, and it improves as hypothyroidism is corrected. ...Read more

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What is the difference between iron deficiency and iron deficiency anemia?

Matter of degree: When iron intake is inadequate for a prolonged period, iron storage in body is depleted. This is called iron deficient state. When this iron deficient state continues and iron store is further depleted, anemia develops, namely iron deficiency anemia. ...Read more

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How serious is iron deficiency anemia?

How serious is iron deficiency anemia?

Severity and cause: Will depend on how severe it is and whether you are pregnant or not. If you only have mild deficiency-you probably don't have any symptom. If severe enough, tired, fatigue, dizziness, chest pain, shortness of breath can be the symptoms. In pregnancy iron is very important for the fetus. It is crucial to know what is the cause. Bleeding? Malabsorption, cancer? Etc- this needs to be found out. ...Read more

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What differences are there in megaloblastic anemia and pernicious anemia?

Pernicious = Vit B12: Megaloblastic anemia refers to any condition which causes large red blood cells (folate (folic acid) deficiency, vitamin B12 deficiency, etc.) pernicious anemia can be thought of as a *type* of megaloblastic anemia which is caused by vitamin B12 deficiency secondary to malabsorption. ...Read more

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How are anemia and iron deficiency different?

Anemia: Anemia refers to low red blood cells. It can be caused by iron deficiency, but there are many other causes of anemia as well. Iron deficiency means there is not enough iron in the body. This is a common cause of anemia. ...Read more

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Why MCHC is low in iron deficiency anemia but normal in pernicious anemia?

Why MCHC is low in iron deficiency anemia but normal in pernicious anemia?

MCHC: MCHC=mean corpuscular hemoglobin concentration This value is a calculated value of hemoglobin per red cell. In iron deficiency the body has difficulty making enough hemoglobin, and the resultant cells are both small and low on hgb. The defect with PA is not with hgb synthesis but with cell replication and nuclear maturation, so the amount of hgb/cell is unaffected. ...Read more

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What are the causes of macrocytic hypochromic anemia?

See below: Macrocytic anemia has several causes. Most common causes are vitamins B12 and folate (folic acid) deficiency, liver disease, alcohol excess. There are other less common causes. ...Read more

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What are problems with untreated, iron deficiency, anemia?

Anemia: Your hemoglobin will go down, and you will end up requiring blood transfusions. Usually there is an underlying problem causing the anemia (most commonly from the intestines or the bone marrow), and this needs to be sorted out. ...Read more

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Can hypothyroidism be the cause of microcytic hypochromic anemia?

Can hypothyroidism be the cause of microcytic hypochromic anemia?

Not usually: Microcytic anemia is usually due to iron deficiency, rather than hypothyroidism. If associated with hypothyroidism, anemia is usually macrocytic (often secondary to pernicious anemia). Either way, an anemia deserves a thorough workup with your medical doctor, and treatment of your hypothyroidism. Best wishes! ...Read more

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Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Cell maturation: B12 and folic acid are need for DNA synthesis and maturation of all cells. The cells affected are not only red cells, white cell, and platelets but almost all cells in the body, including brain and spinal cord cells. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

Dr. Ed Friedlander
287 doctors shared insights

Iron Deficiency Anemia (Definition)

Too few healthy red blood cells due to too little ...Read more


Dr. Oscar Novick
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Iron Poor Blood (Definition)

It may mean any anemia, or ...Read more