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Doctor insights on: Pathophysiology Of Ankylosing Spondylitis

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What are the main causes of juvenile spondylitis, spondyloarthritis?

What are the main causes of juvenile spondylitis, spondyloarthritis?

Inheritance and a...: Genetics play a most important role, together with an inciting trigger, usually a gut or venereal infection. The gene most associated with this is hla-b27, but hla-b40/41 is second. In african american's b7 is more common. Spondylitis requires systemic drugs to treat, not only nsaids like alleve. ...Read more

Dr. Pierre Moeser
194 doctors shared insights

Ankylosing Spondylitis (Definition)

A defect that effects the spine, causing ligaments and other elements of the spine to calcify, making it essentially ...Read more


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What is ankylosing spondylitis?

What is ankylosing spondylitis?

No known cause: Ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. In particular, people who have a gene called hla-b27 are at significantly increased risk of developing ankylosing spondylitis. ...Read more

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What is the difference between rheumatoid arthritis and ankylosing spondylitis?

Difference: They are both rheumatologic conditions, however RA usually has detectable blood markers suggesting joint degeneration in specific patterns as a result of a hyperactive immune response. Ankylosing spondylitis is usually negative for blood markers, but associated with hla b27 antigen. It causes inflammation in the joints of the axial skeleton resulting in fusion of the sacroiliac and spinal segments. ...Read more

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What is ankylosis spondylities?

A form of arthritis : Ankylosing spondylitis is an inflammatory disease of the spine . It is usually seen in younger persons and more commonly in med most commonly see early morning stiffness of at least 30-60 minutes that improves with activity. Nay also see other areas of arthritis rash inflammation in the eye and other symptoms. There is a strong association with a genetic factor called hl-a b27. See a rheumatologis. ...Read more

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What are the symptoms of juvenile rheumatoid arthritis?

What are the symptoms of juvenile rheumatoid arthritis?

Most not JRA!: Children rarely get ccp and rf positive true ra, usually before mid teen years. We now call it "juvenile idiopathic arthritis, " or jia, in recognition that it is usually different. Apart from joint inflammation, fever and rash are much more common. Treatment will vary depending on the age and size of the child. ...Read more

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Treatment of psoriatic arthropathy?

Treatment of psoriatic arthropathy?

Lots of treatments: There are many treatment options for psoriatic arthritis, see a rheumatologist to help you pick the one(s) that fit you best. ...Read more

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What kind of arthritis is polymyalgia rheumatica?

What kind of arthritis is polymyalgia rheumatica?

PMR affects muscles: Polymyalgia rheumatica presents as painful muscles, usually in your shoulders, upper arms and thighs. It is associated with a lab finding, elevated sedimentation rate (ESR) and is treated with oral steroids, usually prednisone. Little is known about what causes pmr, but it is an inflammatory disorder of the muscles. It is seen usually in those aged over 50. ...Read more

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What are the symptoms of an Ankylosing Spondylitis flare up?

Stiffness: I would expect the patient to have spine pain and limited spine bending. Chest expansion, chest size difference between maximum exhale and maximum inhale size is less than 2 inches. Ankylosing Sponlylitis is rare in females ...Read more

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What is polyarticular juvenile idiopathic arthritis?

What is polyarticular juvenile idiopathic arthritis?

Rheumatoid arthritis: This is rheumatoid arthritis that start during the pediatric years and involves many joints. It is an autoimmune disorder ...Read more

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What sort of problem is ankylosing spondylitis?

What sort of problem is ankylosing spondylitis?

Arthritis/inherited: This is an inflammation of the facets of the spine, the sacroiliac joint and rib facets related to an inherited deficiency of bodily antigen (termed hla b27). Treatment is very helpful and it tends to be episodic. The spondylitis part is when the facts fuse causing stiffness of the spine. You should be under the care of a rheumatologist for this as it is best to avoid the crippling aspects. ...Read more

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What is the role of cricoarytenoid arthritis in rheumatoid disease?

What is the role of cricoarytenoid arthritis in rheumatoid disease?

Rare complication?: This is a rare complication of rheumatoid arthritis mentioned in textbooks. It is something to think about for a patient with unexplained vocal cord dysfunction, but in many years of practice i haven't seen a case yet. ...Read more

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Anklosing spondylitis is what?

Anklosing spondylitis is what?

Arthritic condition: Ankylosing spondylitis is a severe disorder that causes fusion of the vertebrae in the spine. The bones are brittle and easily broken. Commonly called "bamboo spine", the spine is prone to fracture. ...Read more

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Can you explain the disease ankylosing spondylitis?

Arthritis: It is form of arthritis, somewhat related to rheumatoid arthritis. It typically affects the spine, joints, heart and eyes. ...Read more

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Is rheumatoid arthritis the affliction as inflammatory arthritis?

Is rheumatoid arthritis the affliction as inflammatory arthritis?

Not really: Ra is one type of inflammatory arthritis but the are many different types of inflammatory arthritis that are unrelated to ra. ...Read more

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How does reiter's syndrome and ankylosing spondilitis differ?

How does reiter's syndrome and ankylosing spondilitis differ?

They differ in : Classic presentation with reiter's known for eye inflammation and urethral inflammation along with large joint arthritis as a reactive inflammation triggered by infection typically while ankylosing spondylitis is just joint involvement primarily axial or spine/pelvis region of no known trigger. ...Read more

Dr. Michael Nelson
232 doctors shared insights

Spondylitis (Definition)

An inflammatory condition of the spine such as ankylosing spondylitis. Spondy = spine ...Read more