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Doctor insights on: Pathophysiology Of Ankylosing Spondylitis

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What are the main causes of juvenile spondylitis, spondyloarthritis?

What are the main causes of juvenile spondylitis, spondyloarthritis?

Inheritance and a...: Genetics play a most important role, together with an inciting trigger, usually a gut or venereal infection. The gene most associated with this is hla-b27, but hla-b40/41 is second. In african american's b7 is more common. Spondylitis requires systemic drugs to treat, not only nsaids like alleve. ...Read more

Dr. Pierre Moeser
194 doctors shared insights

Ankylosing Spondylitis (Definition)

A defect that affects the spine, causing ligaments and other parts of the spine to calcify. In particularly severe cases, ...Read more


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What is ankylosing spondylitis?

What is ankylosing spondylitis?

No known cause: Ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. In particular, people who have a gene called hla-b27 are at significantly increased risk of developing ankylosing spondylitis. ...Read more

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What is the difference between rheumatoid arthritis and ankylosing spondylitis?

Difference: They are both rheumatologic conditions, however RA usually has detectable blood markers suggesting joint degeneration in specific patterns as a result of a hyperactive immune response. Ankylosing spondylitis is usually negative for blood markers, but associated with hla b27 antigen. It causes inflammation in the joints of the axial skeleton resulting in fusion of the sacroiliac and spinal segments. ...Read more

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What is ankylosis spondylities?

A form of arthritis : Ankylosing spondylitis is an inflammatory disease of the spine . It is usually seen in younger persons and more commonly in med most commonly see early morning stiffness of at least 30-60 minutes that improves with activity. Nay also see other areas of arthritis rash inflammation in the eye and other symptoms. There is a strong association with a genetic factor called hl-a b27. See a rheumatologis. ...Read more

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What are the symptoms of juvenile rheumatoid arthritis?

What are the symptoms of juvenile rheumatoid arthritis?

Most not JRA!: Children rarely get ccp and rf positive true ra, usually before mid teen years. We now call it "juvenile idiopathic arthritis, " or jia, in recognition that it is usually different. Apart from joint inflammation, fever and rash are much more common. Treatment will vary depending on the age and size of the child. ...Read more

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Treatment of psoriatic arthropathy?

Treatment of psoriatic arthropathy?

Lots of treatments: There are many treatment options for psoriatic arthritis, see a rheumatologist to help you pick the one(s) that fit you best. ...Read more

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What kind of arthritis is polymyalgia rheumatica?

What kind of arthritis is polymyalgia rheumatica?

PMR affects muscles: Polymyalgia rheumatica presents as painful muscles, usually in your shoulders, upper arms and thighs. It is associated with a lab finding, elevated sedimentation rate (ESR) and is treated with oral steroids, usually prednisone. Little is known about what causes pmr, but it is an inflammatory disorder of the muscles. It is seen usually in those aged over 50. ...Read more

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What are the symptoms of an Ankylosing Spondylitis flare up?

Stiffness: I would expect the patient to have spine pain and limited spine bending. Chest expansion, chest size difference between maximum exhale and maximum inhale size is less than 2 inches. Ankylosing Sponlylitis is rare in females ...Read more

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What is polyarticular juvenile idiopathic arthritis?

What is polyarticular juvenile idiopathic arthritis?

Rheumatoid arthritis: This is rheumatoid arthritis that start during the pediatric years and involves many joints. It is an autoimmune disorder ...Read more

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What sort of problem is ankylosing spondylitis?

What sort of problem is ankylosing spondylitis?

Arthritis/inherited: This is an inflammation of the facets of the spine, the sacroiliac joint and rib facets related to an inherited deficiency of bodily antigen (termed hla b27). Treatment is very helpful and it tends to be episodic. The spondylitis part is when the facts fuse causing stiffness of the spine. You should be under the care of a rheumatologist for this as it is best to avoid the crippling aspects. ...Read more

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What is the role of cricoarytenoid arthritis in rheumatoid disease?

What is the role of cricoarytenoid arthritis in rheumatoid disease?

Rare complication?: This is a rare complication of rheumatoid arthritis mentioned in textbooks. It is something to think about for a patient with unexplained vocal cord dysfunction, but in many years of practice i haven't seen a case yet. ...Read more

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Anklosing spondylitis is what?

Anklosing spondylitis is what?

Arthritic condition: Ankylosing spondylitis is a severe disorder that causes fusion of the vertebrae in the spine. The bones are brittle and easily broken. Commonly called "bamboo spine", the spine is prone to fracture. ...Read more

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Can you explain the disease ankylosing spondylitis?

Arthritis: It is form of arthritis, somewhat related to rheumatoid arthritis. It typically affects the spine, joints, heart and eyes. ...Read more

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Is rheumatoid arthritis the affliction as inflammatory arthritis?

Is rheumatoid arthritis the affliction as inflammatory arthritis?

Not really: Ra is one type of inflammatory arthritis but the are many different types of inflammatory arthritis that are unrelated to ra. ...Read more

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How does reiter's syndrome and ankylosing spondilitis differ?

How does reiter's syndrome and ankylosing spondilitis differ?

They differ in : Classic presentation with reiter's known for eye inflammation and urethral inflammation along with large joint arthritis as a reactive inflammation triggered by infection typically while ankylosing spondylitis is just joint involvement primarily axial or spine/pelvis region of no known trigger. ...Read more

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Can ankylosing spondylitis be cured?

No: This is an inflammation of the facets of the spine, the sacroiliac joint and rib facets related to an inherited deficiency of bodily antigen (termed hla b27). Treatment is very helpful and it tends to be episodic. The spondylitis part is when the facts fuse causing stiffness of the spine. You should be under the care of a rheumatologist for this. ...Read more

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What could cause ankylosing spondylitis?

Unknown, genes: The exact cause is uncertain, but it does seem to have a genetic connection. It is more common in males. It usually starts in early adulthood (occasionally earlier or later), ofter with morning stiffness and back pain. Severe pain, stiffness in a young person in the absence of trauma may be a good reason to see your doctor. Consider a seeing a rheumatologist. ...Read more

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What sort of problem is ankylosing spondylitis?

Arthritis/inherited: This is an inflammation of the facets of the spine, the sacroiliac joint and rib facets related to an inherited deficiency of bodily antigen (termed hla b27). Treatment is very helpful and it tends to be episodic. The spondylitis part is when the facts fuse causing stiffness of the spine. You should be under the care of a rheumatologist for this as it is best to avoid the crippling aspects. ...Read more

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Could you explain what is ankylosing spondylitis?

Could you explain what is ankylosing spondylitis?

Inflammatory spine: Inflammatory disease predominantly of the vertebral column, which eventually causes loss of all back and neck motion and may affect the eyes and other parts of the body. Early initiation of treatment is important. ...Read more

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What cna be done for pain for ankylosing spondylitis?

Medication and : Modalities as well as exercise. Lifestyle changes like weight control & not smoking are important. You should see a rheumatologist for getting the correct medication regimen for you & be guided through an exercises program for maintaining flexibility and correct posture. This may be initiated with physical therapy which can also provide for modalities like ultrasound and myofascial techniques. ...Read more

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What are the concerns with having ankylosing spondylitis?

What are the concerns with having ankylosing spondylitis?

Several things: It is a painful condition early on. Sleeping and resting in the most comfortable position lead to poor posture, and if the disease is full blown and fuses the spine, it ends up fused (stiff) in a bad position. This bent forward position can worsen and interfere with daily life activities. Good medication, good posture, proper therapy can prevent these problems and reduce the need for major surgery. ...Read more

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How to tell if my ankylosing spondylitis is cured or not ?

Ankylosing Spondylit: Ankylosing spondylitis (as) is a chronic inflammatory disease with a strong genetic predisposition of the axial skeleton with variable involvement of peripheral joints. As mainly affects the spine and the sacroiliac joint in the pelvis, and can cause eventual fusion of the spine. Unfortunately, no cure for as is known yet, although treatment and medications will reduce pain and improve mobility. ...Read more

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What is ankylosing spondylitis , what are the causes and cure?

What is ankylosing spondylitis , what are the causes and cure?

No cure. Good Rx.: As is a hereditable arthritis that effects the spine and sij.. It is strongly asociated with the hla-b27 antigen, and to a lesser extent b40, and b7. It causes peripheral tendinitis, plantar faciitis, and periosteal inflammation. Eye problems (iritis and conjuctivitis) occur. It can also (rarely) affect the heart valves. We know infections trigger it, but inflammation of small bowel p[ersists. ...Read more

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Is there a cure for ankylosing spondylitis?

No but there is : Treatment and this would be best guided by a rheumatologist. First, you have to optimize your health in terms of weight control, not smoking & regular exercise along with various combinations of medication options that will be prescribed by the rheumatologist in addition to possible pt and orthopedic consultation. There are now disease modifying drugs as well. ...Read more

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Is there a cure for ankylosing spondylitis?

Treat symptoms: Symptoms and progression can often be treated. See a rheumatologist. ...Read more

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How can you sleep with ankylosing spondylitis ?

Generally, what is : The most comfortable position although with ankylosing spondylitis there is a tendency to become less erect so stomach sleeping may help to counteract that tendency if tolerated. Most people find lying on there backs with the hips and knees slightly flexed or on their sides to be the most comfortable sometimes using a body pillow to help hold this position. ...Read more

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How do complementary doctors treat ankylosing spondylitis?

BE CAREFUL: As can be a serious disease and when progressive the spine can begin to fuse together. This makes chiropractic manipulation potential dangerous, accupuncture, massage, physical therapy under physician's orders and with therapists who know as, and aquatic therapy are options. ...Read more

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Ankylosing spondylitis what are the chances to getting ssd?

Let me explain: The social security administration (ssa) does recognize as as a potentially disabling illness, under its inflammatory arthritis listing. You have to have stiffness of the dorsal or thoracic spine to certain degree. ...Read more

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What are the long term effects of ankylosing spondylitis?

What are the  long term  effects of ankylosing spondylitis?

Deformity/disability: Deformity and disability - without proper treatment. Heart, lung and eye problems appear infrequent. Watch for drug side effects. ...Read more

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Ankylosing spondylitis and tietze are they the same or different?

They are different: Tietze is a an inflammation of the cartilage of the ribs as they attach to the sternum (breast plate). Ankylosing spondylitis is a chronic inflammatory arthritis of the spine and pelvis. ...Read more

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Can you give me suggestions for ankylosing spondylitis and uveitis?

Related: About 20-30% of those with ankylosing spondylitis (as) will develop uveitis. As is a hyper immune state in which the joints along the spine get inflamed and may fuse (spondylosis). The uveitis can be severe but usually responds well to treatment by an ophthalmologist. It has a tendency to recur, but is usually responsive in the same way. ...Read more

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Help! Is it possible to have a baby if you have ankylosing spondylitis?

Help! Is it possible to have a baby if you have ankylosing spondylitis?

Yes: If your pelvic bones are fused you may require a c section for delivery. You may also have to stop your medications prior to becoming pregnant. This will depend on what medications you take ...Read more

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Which unprescripted medicine ismost effective for ankylosing spondylitis?

None: Over the counter meds are generally ineffective but you can try aleve (naproxen) or advil. Unfortunately, these do not prevent progression of the disease. See a rheumatologist for proper treatment. ...Read more

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Is there a difference between ankylosing spondylitis and spondylolisthesis?

Absolutely: Ank spondy is a multisystem disease characterized by inflammation of the ligamentous insertions of the spine. Spondylolisthesis is a congenital instability in the lower back. ...Read more

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What is the difference between ankylosing spondylitis and spondylolisthesis?

Inflammatory v degen: Ankylosing spondylitis (AS) is an inflammatory arthritis that affects the spine, pelvis, and sometimes the peripheral joints as well. Spondylolisthesis is a degenerative change in the spine that allows one vertebra to slide out of alignment with the one next to it. These conditions are treated differently. ...Read more

Dr. Michael Nelson
232 doctors shared insights

Spondylitis (Definition)

An inflammatory condition of the spine such as ankylosing spondylitis. Spondy = spine ...Read more