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Doctor insights on: Pathophysiology Of Amenorrhea

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Dr. Robert Lang
618 doctors shared insights

Amenorrhea (Definition)

Amenorrhea = absence or missing at least ...Read more


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What exact kind of hormonal imbalance causes menorrhagia?

What exact kind of hormonal imbalance causes menorrhagia?

Thyroid/Pituitary: Menorrhagia/Heavy Menstrual Bleeding is any period bleeding that leads to soaking a pad/tampon more than every 2hrs, interferes w/ daily activities, or lasts >7days. There are many causes: fibroids, polyp, hormonal imbalance (TSH/Prog/Estr), adenomyosis, bleeding disorders and cancer. Get checked out. Taking progesterone (pills/IUD) can help to thin the uterine lining so you don't bleed as much. ...Read more

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Pathophysiology of pyelonephritis?

Pathophysiology of pyelonephritis?

Kidney Infection: Pyelonephritis is iinfection in a kidney. It can be caused either by bacteria moving from the skin up the urinary tract and invading the kidney or by bacteria floating around in your blood until they take up residence in your kidney. Either has been given as an explanation for kidney infections and I have not seen anything to say one is more likely than the other. ...Read more

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What are the long-term effects of secondary amenorrhea?

What are the long-term effects of secondary amenorrhea?

Depends: If your amenorrhea is due to just not ovulating or pcos , there are risks of uterine cancer, diabetes and cardiovascular problems. If your amenorrhea is due to being underweight or going through menopause early, the chief concern is bone loss. ...Read more

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What are the long-term effects of secondary amenorrhea?

What are the long-term effects of secondary amenorrhea?

Depends on the cause: If the amenorrhea is due to not ovulating, we worry about uterine cancer and hyperplasia as well as issues that may be related to the cause such as diabetes or heart disease. If the amenorrhea is related to low estrogen such as in anorexia or early menopause, we worry about osteoporosis, and again any medical issues related to the cause. ...Read more

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What are the causes of amenorrhea?

What are the causes of amenorrhea?

Pregnancy first !!: Must rule out pregnancy first ! if no menses prior (called primary amenorrhea) abve age 15yrs, then anatomical causes also must be considered (lack of uterus, blood flow blockage, etc). If menses took place prior (called secondary amenorrhea) then hormonal causes such as elevated prolactin, testosterone or low thyroid should be considered. Significant weight loss also possible. Talk with your pcp. ...Read more

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What are the pathophysiology of anaemia of chronic diseases?

What are the pathophysiology of anaemia of chronic diseases?

Anemia: Really need provide more info concerning age, other conditions- diabetes, heart disease, . The. Most common i encounter are patients with chronic kidney disease. As kidney function decreases, signals to none marrow to produce blood decreased. Kidneys also controll blood pressues, etc. Generally, the body adapts to this type of anemia, treatment only when treatment needed. Other diseases. Space limi. ...Read more

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What is the pathophysiology of diabetes mellitus usually?

What is the pathophysiology of diabetes mellitus usually?

Poor sugar control: Most of the foods you consume is metabolized/changed into sugar (glucose) for body to use (similar to oil refining to gas u use for cars), but the sugar level is nicely regulated to about 60-100 in fasting state. When body can't keep it to this range and it is constantly/mostly high above 125 fasting, it is defined as diabetes. There are other ways to diagnosis diabetes. Consult doc. Good luck. ...Read more

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What is the pathophysiology of syncope?

What is the pathophysiology of syncope?

Decr brain bloodflow: Syncope (loss of consciousness) is caused by reduced blood flow to the brain. Most cases are cardiogenic in nature (for example, arrhythmias), but other causes can include vasovagal response, carotid artery compression, vertebrobasilar system disease, etc. See your primary care provider for further discussion if you've experienced syncope. http://www.ninds.nih.gov/disorders/syncope/syncope.htm ...Read more

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What are the similarities of pcos and non-classical congenital adrenal hyperplasia?

What are the similarities of pcos and non-classical congenital adrenal hyperplasia?

Many similarities: Women with pcos or non-classical cah can have essentially identical symptoms: irregular periods, hirsutism, even virilization, infertility, acne. Both usually have features of metabolic syndrome/insulin resistance. Non-classical cah can have precocious puberty. The test to distinguish the two is a baseline and acth stimulated 17-oh progesterone. An endocrinologist is needed for this situation. ...Read more

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What are the causes of amenorhea?

What are the causes of amenorhea?

Many: Amenorrhea has many causes. Many relate to a deficiency in those hormones from the pituitary gland which stimulate the ovaries (gonadotropins) or an excess of another pituitary hormone, prolactin. This might be from a tumor, a loss of pituitary blood supply, trauma, etc. Or as an aging change (menopause). There are less common local ovarian diseases. ...Read more

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What is the pathophysiology of Aspergers syndrome?

What is the pathophysiology of Aspergers syndrome?

Complex: Asperger syndrome, is thought to represent alterations in brain development resulting from interactions between multiple genes and the environment. Problems in the connections between the amygdala and associated structures of the brain may play a role in the pathogenesis. People with Aspergers have difficulty with memory, facial recognition. ...Read more

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Do the symptoms of congenital adrenal hyperplasia differ by gender?

Yes: Persons with the most common form congenital adrenal hyperplasia (cah) have a predisposition to making extra testosterone. For girls this can manifest as genitalia that is "masculinized" before birth and therefore "ambiguous" at the time of birth. Girls can also have somewhat masculinized behaviors. The testosterone levels can be lowered by therapy. Boys do not have genital or behavioral issues. ...Read more

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What is the pathophysiology of hypoglycemia?

What is the pathophysiology of hypoglycemia?

High insulin: Very common cause of hypoglycemia is high Insulin levels (almost always related to excess sugar and carb intake). Initially the high Insulin causes a reactive hypoglycemia, however over time, the chronically high Insulin levels lead to "insulin resistance". When your Insulin no longer works your blood sugars will rise and you develop diabetes. This is 100% preventable wi proper diet. ...Read more

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What is the physiology and pathophysiology of rheumatic fever?

What is the physiology and pathophysiology of rheumatic fever?

Rheumatic fever: Rheumatic fever is caused by a streptococcal infection triggering a specific immune response. Acutely various joint aches and pains occur accounting for the 'rheumatic' term. Long term the mitral and/or aortic valves are often involved with chronic inflammation and damaged. We see rf rarely in the us now, but sometimes in new immigrants. ...Read more

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What is the pathophysiology behind hyperthyroidism causing amennorhea?

What is the pathophysiology behind hyperthyroidism causing amennorhea?

Low free estradiol: Hyperthyroidism lowers estradiol. Estradiol creates ovulation. Not enough Estradiol - no ovulation. No ovulation - no menses. Oversimplified perhaps, but that's basically it. ...Read more

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What are symptoms of congenital adrenal hyperplasia in girls?

What are symptoms of congenital adrenal hyperplasia in girls?

It varies: Persons with the most common form of congenital adrenal hyperplasia (cah) have a predisposition to make extra testosterone. For girls can manifest as genitalia that is "masculinized" before birth and therefore "ambiguous" at birth. Some girls can also have "salt wasting". Girls can also have somewhat masculinized behaviors. Testosterone levels can be lowered by therapy. www.caresfoundation.org. ...Read more

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What's the pathological physiology of hemochromatosis?

What's the pathological physiology of hemochromatosis?

Iron: 400 characters aren't enough; there are websites, books and journal articles. These folks absorb iron too easily through the gut, and it ends up in the liver, heart, and endocrine pancreas where the atoms generate free radicals that do damage. ...Read more

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What are the symptoms of congenital adrenal hyperplasia?

What are the symptoms of congenital adrenal hyperplasia?

CUSHING's SYNDROME: Sx are moonface, truncal obesity, buffalo hump, slender extremities and fingers, striae of the abdomen, easy bruising and menstrual disorder secondary to elevated corticosteroids. ...Read more

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What is the pathophysiology behind hyperthyroidism causing amennorhea?

Low free estradiol: Hyperthyroidism lowers estradiol. Estradiol creates ovulation. Not enough Estradiol - no ovulation. No ovulation - no menses. Oversimplified perhaps, but that's basically it. ...Read more

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Whats secondary amenorrhea?

Whats secondary amenorrhea?

Peroids stop: Primary amenorrhea is when a woman never had a period. If she has had periods and then they stop that is secondary amenorrhea. ...Read more

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What is secondary amenorrhea?

Lack of periods..: Anytime after you had periods as teenager. Most common cause is pregnancy! ...Read more

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How would you trrat secondary amenorrhea?

Hormone challenge: The first step would be to perform a full history and physical exam at the gyn md's office, and rule out pregnancy. If there is no pregnancy, attempt to determine the cause by an initial Progesterone challenge with a pill for 10 days to "induce withdrawal bleeding". If that fails, other studies may be done including a pelvic ultrasound and ancillary blood testing.. ...Read more

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Could it be something bad if I have amenorrhea?

Could it be something bad if I have amenorrhea?

Probably not: It could be something serious but probably not. However, if it continues it will lead to premature bone loss and that could become serious after several years. ...Read more

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How to treat amenorrhea?

Amenorrhea: First you need to diagnose amenorrhea. What causes it? First concern is a pregnancy., so do a pregnancy test. If it has been prolonged it could be pco syndrome, hypothyroidism, anemia , malnutrition, anovulation. Each of these conditions requires a extensive work-up and plan in order to treat. ...Read more

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What is primary amenorrhea?

What is primary amenorrhea?

No period by age 16: Primary amenorrhea describes a situation in which a girl does not have her first period by age 16. This may or may not be associated with lack of physical changes such as a growth spurt, hair growth in the pubic and underarm areas, and breast development. ...Read more

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Does vit e help amenorrhea?

? dysmenorrhea: Do you mean dysmenorrhea (menstrual pain), or amenorrhea (absent periods)? For dysmenorrhea, taking vitamin e 200 iu twice daily or 500 iu daily starting 2 days before menstruation and continuing through the first 3 days of bleeding seems to reduce menstrual pain severity and duration and decrease blood loss in teenaged girls with primary dysmenorrhea (menstrual pain without anatomic cause). ...Read more

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What causes primary amenorrhea?

Variety of problems: Primary amenorrhea can stem from a variety of causes. These range from problems with the uterus and or outflow tract, to problems with the brain regulation of the ovaries or problems with the ovaries themselves, to amenorrhea due to too little body fat or too excessive stress. Some girls will simply have delayed puberty without any identifiable cause as well. Girls who have not started sexual development by the age of 14 or have not had menstrual cycles by the age of 16 merit evaluation by an endocrinologist. ...Read more

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Does exercise induce amenorrhea?

Excessive - yes: Excessive exercise and stress are known to induce amenorrhea via a mechanism involving the brain and the pituitary gland within it. This is particularly a problem in teenage girls who take part in competitive sports or long distance running (or have eating disorders), where such can lead to loss of bone mineral density due to relative estrogen deficiency, and even fractures. ...Read more

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Can ovulation occur in amenorrhea?

No : By definition amenorrhea is lack of ovulation. However, women with amenorrhea can resolve spontaneously and ovulate. ...Read more

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Can a person ovulate with amenorrhea?

Yes: It's not the commonest situation, but absence of periods doesn't necessarily mean infertility. ...Read more

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Can you ovulate if you have amenorrhea?

Sometimes: Although amenorrhea often signals that ovulation isn't happening, you shouldn't assume that you can't get pregnant just because you aren't having regular periods. If you are trying to get pregnant, and have questions about your cycle, you should see a healthcare provider. Similarly, if you aren't having periods and you did previously, you should get checked out! ...Read more

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How to treat amenorrhea without use of bc?

There are: A variety of mental and physical causes of amenorrhea and they have different potential treatments. Best discuss w/your doctor to get a specific diagnosis and treatment just for you. ...Read more

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What could be the cause of the primary amenorrhea?

Several : It could just be late puberty, but it could be a pituitary problem (like prolactin over secretion or pituitary hormone deficiencies), an ovarian problem (like turners syndrome) or a structural problem (like congenital absence if the uterus). Depending on age and family history, a thorough work up should be done. ...Read more

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Post-pill amenorrhea? What is that? A side effect?

Post-pill amenorrhea? What is that? A side effect?

Some women...: ...Stop having their menstrual period for awhile after stopping their birth control pill. It's a side effect, yes. ...Read more

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What are some possible cures of primary amenorrhea?

No one always works: There are many unrelated causes for primary amenorrhea so the cause must be determined to find out if there is a cure. ...Read more

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Can you conceive when you have secondary amenorrhea?

2ndary infertility: Yes, but usually with special assistance and/or resolution of the central or hypothalamic-pituitary problem triggering the amenorhea. For example, excessive exercise is a cause of amenorrhea which will resolve with lighter exercise. Post-pill amenorrhea may take a variable time to resolve. ...Read more

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What do any of you feel works for secondary amenorrhea?

See your OB GYN: Secondary amenorrhea can have many causes - pregnancy, menopause, breast feeding, brain tumors, medications, intense exercising etc. You should see an obgyn to ascertain the etiology behind your amenorrhea and get the care you need! ...Read more

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What are the long-term effects of secondary amenorrhea?

Depends: If your amenorrhea is due to just not ovulating or pcos , there are risks of uterine cancer, diabetes and cardiovascular problems. If your amenorrhea is due to being underweight or going through menopause early, the chief concern is bone loss. ...Read more

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What are the long-term effects of secondary amenorrhea?

Depends on the cause: If the amenorrhea is due to not ovulating, we worry about uterine cancer and hyperplasia as well as issues that may be related to the cause such as diabetes or heart disease. If the amenorrhea is related to low estrogen such as in anorexia or early menopause, we worry about osteoporosis, and again any medical issues related to the cause. ...Read more