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Doctor insights on: Pathophysiology For Hypertensive Chronic Kidney Disease

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What is the pathophysiology of chronic kidney disease?

What is the pathophysiology of chronic kidney disease?

Multiple reasons: Genetics Congenital disorders with altered kidney size, shape, function Medications auto immune disorders Diabetes These are common causes of alterations in kidney function that work by either harming the structure, blood flow or function of the kidney ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


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What can cause chronic kidney disease?

What can cause chronic kidney disease?

Many issues: Diabetes and high blood pressure are the commonest causes. Others are chronic kidney infections, kidney stones, obstruction to the flow of urine, and inherited kidney disorders. ...Read more

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How can I care for chronic kidney disease?

How can I care for chronic kidney disease?

W. nephrologist help: Cause of chronic kidney disease should be determined & treated or stop medications, like Aspirin etc. which might be responsible. Reduce protein intake, especially red meat, also salt. May require medications to control blood pressure &/or fluid retention. All best managed by kidney Dr/nephrologist. Good Luck. ...Read more

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Is chronic Kidney disease reversible , how is this done?

Is chronic Kidney disease reversible , how is this done?

Usually not: However, the diagnosis if made only on labs may be bogus. A well-muscled man with a high creatinine may be told he has low GFR when he does not. Chronic disease can't be diagnosed except over time. Anyone's kidneys can be temporarily impaired by Motrin. And some loss of kidney function is part of getting older. Best wishes. ...Read more

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If chronic kidney disease is so serious, why don’t I feel sick?

If chronic kidney disease is so serious, why don’t I feel sick?

Slow Onset: Chronic kidney disease comes on slowly over a long time. Your body is able to adjust and "get used to" the change. In acute disease, the onset is very fast, no time to adjust and you would feel very ill. Either kind can lead to kidney failure, and eventual dialysis or transplant. ...Read more

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How can chronic kidney disease affect homeostatic mechanisms?

How can  chronic kidney disease affect homeostatic mechanisms?

Too complex: In short, it increases salt and water retention and potassium and magnesium and phosphorus retention depending on degree of ckd. Also increases PTH and decreases vit d due to elevated hormone called fgf 23. Less urine excretion is the reason for the retained electrolytes. Edema and weak bone result & high bp. ...Read more

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How effective is cinacalcet for treating chronic kidney disease?

How effective is cinacalcet for treating chronic kidney disease?

Not at all: cincalcet is specifically for the treatment of hyperparathyroidism, not kidney failure. But... hyperparathyroidism is the result of kidney failure, so it is used in kidney failure often. ...Read more

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What are the differences between nephropathy and chronic kidney disease?

What are the differences between nephropathy and chronic kidney disease?

Close, semantics: Nephropathy means kidney condition. So you could have diabetic nephropathy, hypertensive nephropathy, or uric acid nephropathy. A chronic kidney disease (ckd) means a long-term kidney disease that is not amenable for correction. It also could have many different causes. Above examples of nephropathy are also chronic kidney diseases but uric acid nephropathy is possibly curable so it is not ckd. ...Read more

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I have a chronic kidney disease and am in a lot of pain, what should I do?

I have a chronic kidney disease and am in a lot of pain, what should I do?

Determine Cause: Pain associated with chronic kidney disease is addressed by first identifying the cause of the pain and then addressing the cause specifically. ...Read more

Dr. Katharine Cox
19 doctors shared insights

Chronic Kidney Disease (Definition)

Chronic kidney disease (CKD), also known as chronic renal disease, is a progressive loss in renal function over a period of months or years. Chronic kidney disease is identified by a blood test for creatinine. Higher levels of creatinine indicate a decreased capability of the kidneys ...Read more


Dr. Tarek Naguib
2,382 doctors shared insights

Kidney Diseases (Definition)

Kidney diseases include hereditary problems such as polycystic kidney disease, structural abnormalities, infections, cancer, and damage to kidneys due to other medical conditions ...Read more