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Doctor insights on: Pathologists

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Finding thyroid expert ? Reading tells me large percentage of thyroid/nodules removed are benign. Medical papers refer to finding needle in haystack.

Finding thyroid expert ? Reading tells me large percentage of thyroid/nodules removed are benign. Medical papers refer to finding needle in haystack.

Cancer < 5%: Thyroid nodules are very common, especially as we get older. You are correct, most thyroid nodules removed are benign. There is a small risk of cancer in most nodules, but the risk goes up with significant medically history, like family history of thyroid cancer or history of neck radiation. ...Read more

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How to interpret specific findings on Pap test. Reads as: atypical immature metaplastic Cells are present. Research confused me more?

How to interpret specific findings on Pap test. Reads as: atypical immature metaplastic Cells are present. Research confused me more?

No cancer: Some of the cells are abnormal but no cancer. Please follow you doctor's instructions for repeating PAP smears. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Do benign tumors arise by transformation?

Do benign tumors arise by transformation?

Yes: All tumors arise from normal pre existing cells that have undergone some form of transformation. Several oncogenes are turned on to present the benign as well as malignant lesion with immortality. In the case of the malignant tumor additional changes allow for matrix metalloproteinase to be produced to dissolve walls of blood vessels for metastasis and convert e-cadherin to small e cad. ...Read more

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Is stromal fibrosis commonly mistaken with breast cancer? I was told about radiology pathology discordance

Is stromal fibrosis commonly mistaken with breast cancer? I was told about radiology pathology discordance

Final by pathologist: Yes fibrosis may show in mammography as suspicious but pathologist with trained eye will not mistake it for cancer. Pathologist will give final answer weather is malignant or non malignant fibrosis . Tissue examination is final answer ...Read more

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My mom has needle aspiration biopsy and the results were: follicular neoplasm adenoma vs carcinoma; adenomatous colloid goiter with hyperplastic chang?

It could be cancer/T: Thyroid cancer can show up like this. On the other hand benign Thyroid nodules are common but FNA may not be adequate to make a correct diagnosis. You should seek an expert opinion from a Thyroid Cancer doctor. Such specialists are found in bigger Medical centers or in a Cancer hospital where you could first go to an Endocrinologist or head and Neck surgeon for advice. ...Read more

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Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Yes: Adenocarcinoma in situ is cancer. The area suggestive of micro invasion suggests you should have rather aggressive followup screening which I am sure your doctor has, or will soon suggest. Stay on top of this and follow his/her advice. ...Read more

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Biopsy done on nodule by tonsil states "reactive lymphoid hyperplasia with focal squamous metaplasia." does that mean I have oral HPV (oral warts)?

Biopsy done on nodule by tonsil states "reactive lymphoid hyperplasia with focal squamous metaplasia." does that mean I have oral HPV (oral warts)?

Not necessarily: The description you provided only points to chronic inflammation without any indication of the causative factor. Hpv infection can be tested for specifically in a biopsy and you may wish to discuss that with your doctor. ...Read more

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Thyroid u/s finding suspicious for malignancy with small flecks of calcification in irregular hypoechoic solid nodule but 3 biopsies are benign

Thyroid u/s finding suspicious for malignancy with small flecks of calcification in irregular hypoechoic solid nodule but 3 biopsies are benign

"Suspicious": doesn't mean there is cancer, it only means there is some probability of cancer, which could be as low as 10%. Biopsy is the gold standard. If the biopsy is negative and shows a specific benign process that accounts for the nodule(concordant), then it is likely not cancer. ...Read more

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Abundant benign appearing follicular epithelial cells, hemosiderin-laden macrophages and colloid present, favor adenomatoid nodule. ?

Glad to hear it: Your thyroid nodule is benign. You may have several and they are probably benign as well. Nobody knows what causes these little adenomatous nodules, but they have very little tendency to turn bad. ...Read more

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My pap smear and my results were endocervical/transformation zone component atypical squamous cells of undetermined significance?

My pap smear and my results were  endocervical/transformation zone component atypical squamous cells of  undetermined significance?

Follow up needed: You should discuss follow up with your doctor. Typically a colposcopy is recommended to look closer at your cervix. ...Read more

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Got13small inactive demyelinations in the brain.Neurologists said not ms-demyelinations disposed different.Is pet scan enough to confirm or infirm ms?

Got13small inactive demyelinations in the brain.Neurologists said not ms-demyelinations disposed different.Is pet scan enough to confirm or infirm ms?

Will not help: Your lesions might be due to head injury smoking, hypertension, or migraine but could also be RIS, an early sign of MS. PET WON't dfferentiate but spinal tap or repeat MRI both brain and neck in 6 months might be considered ...Read more

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Are pancreatic malignant tumors hypoechoic ?

Are pancreatic malignant tumors hypoechoic ?

Yes: The typical echogenicity of the pancreas is hyperechoic to adjacent fat. A hypoechoic mass within the pancreas can be benign or malignant. If you have a hypoechoic mass in the pancreas at age 30, you should undergo an MRI or ct of the abdomen to evaluate it further unless by ultrasound it is obviously cystic. ...Read more

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Are thyroid nodules with microcalcifications always cancerous?

Are thyroid nodules with microcalcifications always cancerous?

No: Thyroid nodules with calcifications need to be fully evaluated, but just because they have calcifications, doesn't mean that they are cancerous. Don't delay, get evaluated. ...Read more

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HEMATOLOGY DEPT. WBC 14.5H LYMPH# 4.9H, MONO# 0.9H, GRAN#8.6H .. Help interpret please?

HEMATOLOGY DEPT.  WBC 14.5H LYMPH# 4.9H, MONO# 0.9H, GRAN#8.6H .. Help interpret please?

Abnormal WBC: Your white blood cell count and immature white cells are elevated, which may signal an infection. Prednisone can also cause an elevated WBC. Comparing to the laboratory standard is helpful, if you have it. Also, no sure why you had the test - what are your symptoms? ...Read more

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What doctors specialize in sarcoidosis treatments?

What doctors specialize in sarcoidosis treatments?

Pulmonologist: Sarcoidosis is a condition where inflammatory deposits can localize in multiple sites in the body, but most commonly the clinical findings are most prevalent in the lungs (hilar adenopathy, micronodule deposition in lung tissue). Changes in pulmonary function studies, coughing, and dyspnea might occur. In heart, sarcoidosis can result in arrhythmias, and cardiomyopathy. ...Read more

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Who usually performs colonoscopies, gastroenterologists or colon and rectal surgeons?

Who usually performs colonoscopies, gastroenterologists or colon and rectal surgeons?

Both: Both do however if a mass is there the colon and rectal surgeon can take care of it. In addition a colorectal surgeon would be more agressive at removing a polyp whereas a GI may be more apt to recommend surgery. This is based on personal experience. Fyi colonoscopy was pioneered by a general and cardiothoracic surgeon at beth israel in ny. Dr wolff and dr shinya invented polypectomy. ...Read more

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