Doctor insights on:
Partial Central Diabetes Insipidus
Can partial central diabetes insipidus go away or improve? After 2yrs needing ddavp to control, eventually urine started to concentrate without it.
I have seen: one patient in which this happened, but it is very uncommon if the diagnosis is made correctly. Check w/your doctor. ...Read more
Presistent increased frequency of emptying bladder, urinating, as a symptom of a disease state. 2 types: Mellitus (high blood glucose) & Insipidus (inadequate anti-diuretic hormone). In Diabetes mellitus, the far more common, glucose concentrations are ↑ed due to combination of 8 organ system changes referred to as the "ominous octet" & aggravated by intake of sugars (simple & complex ...Read more
Dx'd w/partial idiopathic central diabetes insipidus 20yrs ago by H20deprivation test. Put on DDAVP. No longer needed DDAVP after 2 yrs.Sx better.Why?
Central DI: Hard to answer. It was called "idiopathic", meaning no clear cause. In a 13 yr old, the causes could include a tumor, certain medications, trauma/surgery, meningitis, etc. It is possible that something happened back then but then resolved. Is it possible that you now still have partial DI? Under usual conditions, don't need DDAVP, but under water stress you may. See your Endocrinologist. ...Read more
Is central diabetes insipidus related to adrenal insuffiency? Im having an ACTH test to check adrenal function.
Can be: Hi. If you have Addison's (skin, crease, gum, and scar darkening, malaise, nausea, dizziness, vital signs abnormalities, electrolyte abnormalities, etc), your ACTH will be very high. Addison's is most commonly an autoimmune disease. At least a subset of idiopathic central DI appears to be autoimmune in nature, and the risk of that goes up with other autoimmune diseases. If real, you got 2 rare 1's ...Read more
Besides head injury, pregancy, surgery,or pituitary tumor, what can cause one to have transient central diabetes insipidus? autoimmune?
Hard to say: Hi. I'd like to see the evidence for transient DI. Most autoimmune DI (for which there is no clinical lab test...yet) is not transient as far as we know, although that would be high on the list of suspects for a transient DI, in my opinion, having excluded the other causes you mention. Consider yourself fortunate if it's transient! Happy 2015! ...Read more
Diabetes insipidus: 400 characters are too few to answer your question. In general, the doctor will look at a 24-hour urine collection for determination of urine volume, serum electrolyte concentrations and glucose level, urinary specific gravity, simultaneous plasma and urinary osmolality, and plasma ADH level. It may also include a water deprivation test, MRI, etc. ...Read more
Complicated: The answer to this question should be given face to face with your physician as it can be a little technical to explain. ...Read more
Follow doc's advise: You need to find out the cause so you can be treated appropriately. Often time, diabetes insipidus is just a symptom, not the cause. The hormone involved is ADH (antidiuretic hormone). If the cause is in the brain, treatment is to give back ADH (ddavp) either in nasal spray or pill. If the problem is at the kidney, treatment is antiinflammatory (indomethacin) and diuretics (hctz and amiloride). ...Read moreSee 1 more doctor answer
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