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Parkinson's disease is associated with a misfolded protein (alpha synuclein) which causes a loss of Dopamine in the basal ganglia. Symptoms include resting tremors, dementia, gait instability, rigidity, masked facies, drooling, trouble swallowing, constipation, pain, immobilization, and eventual severe disability. Deep brain stimulation may ...Read more
Yes: The older antipsychotics such as thorazine, mellaril, stelazine, haloperidol, turned out to be at high risk in causing tardive dyskinesia. The newer agents such as risperdal, seroquil, geodon, (ziprasidone) have a substantially lower risk but still possible in some patients. ...Read moreSee 1 more doctor answer
A few reasons: First there are two different drug induced parkinsons. Acutely (in which case just stop the drug), and chronically (tardive dyskinesia...TD). TD is generally in those with psychosis. Levodopa can make that worse. Bad. AND, Levodopa has been associated with more rapid progression in regular Parkinsons, so we dont like to use it in anyone if we can avoid it. ...Read moreSee 1 more doctor answer
Off label: Situations which are non-fda approved. Virtually any cognitive loss or condition which affects intellect. For stroke-caused dementia, perhaps donepezil or galantamine (galantamine hydrobromide). For ms cognitive changes, both donepezil and rivastigmine fail, but maybe galantamine (galantamine hydrobromide) helps here. Parkinson's dementia very different from alz, and Exelon patch likely best. Head trauma hard to decide. ...Read moreSee 1 more doctor answer
Yes: They both have advantages and disadvantages. To learn about the risks and benefits to make a decision you should consult your doctor. ...Read more
MAO-B inhibitors: Both selegiline (eldepryl) and Rasagiline (azilect) are mao-b inhibitors, with a couple important differences. Azilect (rasagiline) is much more specific for mao-b, meaning no risk of serotonergic crisis when used alongside ssri antidepressants (celexa, lexapro, etc). Azilect (rasagiline) is also the only neuroprotective drug for parkinson's. Take care! ...Read moreSee 2 more doctor answers
Early vs later stage: Both relieve symptoms of the disease & focus on neurotransmitters key to memory and learning. Aricept focuses on acetycholine in an attempt to slow its loss because of alzheimer's. Namenda (memantine) focuses on glutamate, blocking the excess produced as a part of the disease. Namenda (memantine) is better suited to moderate to advanced stages of alzheimer's, while Aricept is for early onset through advanced stages. ...Read moreSee 1 more doctor answer
Which causes asthenia after not taking; 1-Haloperidol
Yes: All medications can have side effects or complications. This must be weighed against the risk of not treating. Dopamine agonists can cause insomnia, tolerance, hallucinations and agitation. Ldopa used for RLS is usually at a low dose with minimal risk but for parkinsons the above complications should be looked for. Adhd medications have potential for abuse in patients who don't have true adhd. ...Read moreSee 2 more doctor answers
Several: The mainstays of parkinsons treatment are Dopamine agonists such as Requip and the drug l-dopa (sinemet). Others include comtan, (entacapone) amantadine, selegeline, cogentin. Even ECT can be used in severe cases and there is also experimental surgery. Talk to your neurologist to see what is right for you or your loved one. ...Read moreSee 1 more doctor answer
Would not recommend!: Procyclidine is an anti-cholinergic medication which can be used to treat pd, similar to Artane & cogentin. They have fallen out of favor due to multiple side effects & modest anti-pd symptom benefits. A much better choice would be azilect, then Requip xl or neupro, (rotigotine) then eventually sinemet. Stay physically, mentally & spiritually (if important to you) active to keep your self in best shape :) rmh. ...Read moreSee 1 more doctor answer
Do any of these drug combinations work? Prozac abilify, (aripiprazole) Prozac zyprexa, wellbutrin zyprexa, for schizophrenia.
Are there extrapyramidal symptoms occur with thorazine, haldol, (haloperidol) mellaril, or cardiazem?
Some: Yes for the first 3 which are 1st generation antipsychotic meds. I've not heard of it or suspect for cardiazem (diltiazem) which is a heart med. Extrapyramidal sx (eps) include: tremors, stiffness, restlessness. They can be managed by dosage reduction, change in med or by giving meds that counter such as cogentin, propranolol, amantadine and sometime ativan. ...Read more
Is SNRI drugs better than SSRI drugs for people with Parkinson’s depression? Does one work better than the other for Parkinson's patients?
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