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Doctor insights on: Parkinsonism Drugs

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Does stopping anti-psychotic medications reverse antipsychotic-induced diabetes?

Does stopping anti-psychotic medications reverse antipsychotic-induced diabetes?

Not necessarily: There is not a lot known. It may reverse if you lose weight and follow a healthy diet. However, it may be permanent. It is a good idea to have your blood sugar monitored while on an antipsychotic so that any changes can be addressed quickly. ...Read more

Parkinsonism (Definition)

Parkinson's disease is associated with a misfolded protein (alpha synuclein) which causes a loss of Dopamine in the basal ganglia. Symptoms include resting tremors, dementia, gait instability, rigidity, masked facies, drooling, trouble swallowing, constipation, pain, immobilization, and eventual severe disability. Deep brain stimulation may ...Read more


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Do antipsychotic drugs often cause tardive dyskinesia?

Do antipsychotic drugs often cause tardive dyskinesia?

Yes: The older antipsychotics such as thorazine, mellaril, stelazine, haloperidol, turned out to be at high risk in causing tardive dyskinesia. The newer agents such as risperdal, seroquil, geodon, (ziprasidone) have a substantially lower risk but still possible in some patients. ...Read more

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Drugs likeclopomide causes insomnia?

Drugs likeclopomide causes insomnia?

Not likely: The only reason for sleep problem may be that you might have to go to the bathroom more often during the night. ...Read more

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Levodopa is ineffective in drug induced parkinsonism, why?

Levodopa is ineffective in drug induced parkinsonism, why?

A few reasons: First there are two different drug induced parkinsons. Acutely (in which case just stop the drug), and chronically (tardive dyskinesia...TD). TD is generally in those with psychosis. Levodopa can make that worse. Bad. AND, Levodopa has been associated with more rapid progression in regular Parkinsons, so we dont like to use it in anyone if we can avoid it. ...Read more

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Why levodopa not used in drug induced parkinsonism?

Levodopa: Because it elevates Dopamine in the brain, & that can exacerbate the original symptoms to begin with, ex. Psychosis. ...Read more

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What alzheimer's drugs are prescribed for non-alzheimer's conditions?

What alzheimer's drugs are prescribed for non-alzheimer's conditions?

Off label: Situations which are non-fda approved. Virtually any cognitive loss or condition which affects intellect. For stroke-caused dementia, perhaps donepezil or galantamine (galantamine hydrobromide). For ms cognitive changes, both donepezil and rivastigmine fail, but maybe galantamine (galantamine hydrobromide) helps here. Parkinson's dementia very different from alz, and Exelon patch likely best. Head trauma hard to decide. ...Read more

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Can naltrexone combat Parkinson's disease?

Can naltrexone combat Parkinson's disease?

???: Naltrexone is used for opioid dependence. I have not heard of it being used for parkinson disease. ...Read more

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Expert opinions? Which alzheimer's drug is more effective: Aricept or namenda (memantine)?

Expert opinions? Which alzheimer's drug is more effective: Aricept or namenda (memantine)?

Yes: They both have advantages and disadvantages. To learn about the risks and benefits to make a decision you should consult your doctor. ...Read more

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Is selegiline effective as azilect (rasagiline) for parkinsons?

Is selegiline effective as azilect (rasagiline) for parkinsons?

MAO-B inhibitors: Both selegiline (eldepryl) and Rasagiline (azilect) are mao-b inhibitors, with a couple important differences. Azilect (rasagiline) is much more specific for mao-b, meaning no risk of serotonergic crisis when used alongside ssri antidepressants (celexa, lexapro, etc). Azilect (rasagiline) is also the only neuroprotective drug for parkinson's. Take care! ...Read more

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Which alzheimer's drug is most effective: Aricept or namenda (memantine)?

Which alzheimer's drug is most effective: Aricept or namenda (memantine)?

Early vs later stage: Both relieve symptoms of the disease & focus on neurotransmitters key to memory and learning. Aricept focuses on acetycholine in an attempt to slow its loss because of alzheimer's. Namenda (memantine) focuses on glutamate, blocking the excess produced as a part of the disease. Namenda (memantine) is better suited to moderate to advanced stages of alzheimer's, while Aricept is for early onset through advanced stages. ...Read more

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Can exelon, (rivastigmine) aricept, or, namenda treat Lewy body dementia?

Can exelon, (rivastigmine) aricept, or, namenda treat Lewy body dementia?

No: No treatment is yet available for lewy body dementia. However, these might help alleviate some symptoms temporarily. ...Read more

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Fluphenazine and tardive dyskinesia relationship?

Fluphenazine and tardive dyskinesia relationship?

Could be: Any of the sedative hypnotic medications of that class can be associated with tardive dyskinesia- especially those like thorazine, (chlorpromazine) fluphenazine, piperazines and even butyrphenones. ...Read more

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Are citalopram and risperidone MAOI drugs?

Are citalopram and risperidone MAOI drugs?

No: Citalopram is a selective serotonin re uptake inhibitor and is an antidepressant , resperidone is a monoamine antagonist and is a second generation antipsychotic . ...Read more

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Which causes asthenia after not taking; 1-Haloperidol 2-Carbamazepine 3-Lamotrigine 4-Biperiden 5-Methocarbamol 6-Quetiapine 7-Clomipramine?

Which causes asthenia after not taking; 1-Haloperidol  
2-Carbamazepine
3-Lamotrigine
4-Biperiden
5-Methocarbamol
6-Quetiapine
7-Clomipramine?

Asthenia : Weakness can be caused by induction of an adrenal deficiency in the setting of chronic steroid use ( withdrawal ) Any of the medications listed can produce perceived weakness in the setting of anxiety. ...Read more

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Can dopamine agonists like add drugs and levadopa cause problems?

Can dopamine agonists like add drugs and levadopa cause problems?

Yes: All medications can have side effects or complications. This must be weighed against the risk of not treating. Dopamine agonists can cause insomnia, tolerance, hallucinations and agitation. Ldopa used for RLS is usually at a low dose with minimal risk but for parkinsons the above complications should be looked for. Adhd medications have potential for abuse in patients who don't have true adhd. ...Read more

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What drugs help with Parkinson's disease?

What drugs help with Parkinson's disease?

Several: The mainstays of parkinsons treatment are Dopamine agonists such as Requip and the drug l-dopa (sinemet). Others include comtan, (entacapone) amantadine, selegeline, cogentin. Even ECT can be used in severe cases and there is also experimental surgery. Talk to your neurologist to see what is right for you or your loved one. ...Read more

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Procyclidine tablets treat Parkinson's disease?

Procyclidine tablets treat Parkinson's disease?

Would not recommend!: Procyclidine is an anti-cholinergic medication which can be used to treat pd, similar to Artane & cogentin. They have fallen out of favor due to multiple side effects & modest anti-pd symptom benefits. A much better choice would be azilect, then Requip xl or neupro, (rotigotine) then eventually sinemet. Stay physically, mentally & spiritually (if important to you) active to keep your self in best shape :) rmh. ...Read more

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Do any of these drug combinations work? Prozac abilify, (aripiprazole) Prozac zyprexa, wellbutrin zyprexa, for schizophrenia.

Do any of these drug combinations work? Prozac abilify, (aripiprazole) Prozac zyprexa, wellbutrin zyprexa, for schizophrenia.

Yes: Antidepressants, mood stabilizers, and antipsychotic medications are often combined to treat schizophrenia. The decision is best made by the treating psychiatrist and the patient. ...Read more

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Are there extrapyramidal symptoms occur with thorazine, haldol, (haloperidol) mellaril, or cardiazem?

Are there extrapyramidal symptoms occur with thorazine, haldol, (haloperidol) mellaril, or cardiazem?

Some: Yes for the first 3 which are 1st generation antipsychotic meds. I've not heard of it or suspect for cardiazem (diltiazem) which is a heart med. Extrapyramidal sx (eps) include: tremors, stiffness, restlessness. They can be managed by dosage reduction, change in med or by giving meds that counter such as cogentin, propranolol, amantadine and sometime ativan. ...Read more