Doctor insights on:
Why can t healthy dopaminergic neurons be moved into the area of parkinson s affected neurons to treat parkinson s disease ?
Not so simple: Most of the dopaminergic neurons end in the substantia nigra of the midbrain, originating in various deep brain structures. These nerves are already affected by the disease. Unaffected nerves of course still remain but remain connected to brainstem. So outside nerve cells (from another source like stem cells are needed) nerves don't like to be moved around anyway, because they often die. ...Read more
How long is safe to take gabapentin for rls? I´m afraid the long term use can cause parkinson´s disease... Is it possible to happen?
Safety: Gabapentin has been around since early 1970s and used for lots of conditions into the very high doses. Typically no causative issues with degenerative problems like parkinsons. With that being said, it does have side effects. With any medications you have weigh benefit vs. Risk. For RLS doses, typically side effects are minimal. Have treated people upwards of 10 years with Gabapentin ... ...Read moreSee 1 more doctor answer
Complicated: With the earliest symptoms, best approach is Dopamine agonist (mirapex, requip), later l-dopa, which remains fundamental, and maybe Azilect for potential protection. As the l-dopa becomes less efficacious, comtan, and even later combinations of all of the above, and if inadequate, use of deep brain stimulation. ...Read moreSee 2 more doctor answers
Slows gait: Parkinson's slows movements and makes steps smaller. There are also balance difficulties and increased falls. Posture is often bent forward though there is a tendency to fall backwards known as retropulsion. These problems can be mild early on in the illness but can be debilitating if you have had the disease for a number of years. ...Read more
Parkinson Disease: There are a number of medications available for Parkinson disease but see which might be best for the patient you need to have a consultation with a neurologist who deals with this disorder - this physician can best assess which would be the best medication. ...Read moreSee 1 more doctor answer
No remedies (cures): Parkinson's disease is unfortunately a progressive neurological disorder for which there is no remedy or cure at this time. However, there are many options for treatment, and with proper management of medications, exercise and other treatments patients can often do well for many years. ...Read moreSee 1 more doctor answer
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