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Doctor insights on: Parkinson's Disease

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Is parkinson’s disease hereditary?

Yes: Although the causes are multifactorial and sometimes poorly understood, there is a hereditary component. Keep in mind, that even though a parent may have it, it does not mean that it will be necessarily passed on. The tendency, however, may be there. ...Read more

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Can toxic substances cause parkinson’s disease?

Can toxic substances cause parkinson’s disease?

Parkinsonism: Yes. There is evidence that certain chemicals and pesticides can cause parkinsonism. We are now experiencing an epidemic of parkinsonism but it is not clear why this is happening. ...Read more

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Why can t healthy dopaminergic neurons be moved into the area of parkinson s affected neurons to treat parkinson s disease ?

Why can t healthy dopaminergic neurons be moved into the area of parkinson s affected neurons to treat parkinson s disease ?

Not so simple: Most of the dopaminergic neurons end in the substantia nigra of the midbrain, originating in various deep brain structures. These nerves are already affected by the disease. Unaffected nerves of course still remain but remain connected to brainstem. So outside nerve cells (from another source like stem cells are needed) nerves don't like to be moved around anyway, because they often die. ...Read more

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Can dysarthria due to parkinsons' s disease be cured?

Can dysarthria due to parkinsons' s disease be cured?

Control perhaps: Parkinson's disease is a progressive disorder, which responds to several medicines, but cannot be cured at this time. The speech problems may respond to medication adjustments, and perhaps benefit if deep brain stimulation is used. Sometimes speech therapy might work. ...Read more

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How long is safe to take gabapentin for rls? I´m afraid the long term use can cause parkinson´s disease... Is it possible to happen?

How long is safe to take gabapentin for rls? I´m afraid the long term use can cause parkinson´s disease... Is it possible to happen?

Safety: Gabapentin has been around since early 1970s and used for lots of conditions into the very high doses. Typically no causative issues with degenerative problems like parkinsons. With that being said, it does have side effects. With any medications you have weigh benefit vs. Risk. For RLS doses, typically side effects are minimal. Have treated people upwards of 10 years with Gabapentin ... ...Read more

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What are the causes of parkinson disease?

What are the causes of parkinson disease?

Causes of PD: Parkinson's disease involves depletion of a neurotransmitter in the part of the brain called the substantia nigra. The precise mechanisms of neurodegeneration in pd are unknown. There is believed to be an interaction between genetic and environmental factors, abnormalities in protein processing, oxidative stress, mitochondrial dysfunction, and others. ...Read more

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What are some meds for parkinson disease?

What are some meds for parkinson disease?

Numerous ITEMS: We have the anti-cholinergics like artane, but not used much these days, Dopamine agonists such as mirapex, requip, Neupro (rotigotine) patch. L-dopa with or without carbi-dopa, and maybe later entacapone. Azilect may be neuroprotective. The dbs unit could provide surgical support. ...Read more

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How does parkinson disease affect the body?

How does parkinson disease affect the body?

Many possibilities: Physical symptoms: resting tremor, slow movements, rigidity (stiffness) of muscles & posture. Causing slow walking, masked face, decreased blink rate, softer/mumbled speech, poor hand agility, small handwriting, potential falls & injury. Non-physical symptoms: cognitive decline, hallucinations/delusions, anxiety/depression, insomnia, sleepiness/fatigue, constipation, low bp, erectile dysfunction. ...Read more

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Is there a way to cure parkinson disease naturally?

Is there a way to cure parkinson disease naturally?

No cure: There is no cure for parkinson disease. There are many good medications, and exercise helps as well. There is nothing "natural" that has been shown to be helpful. Previously it was thought that coq10 was helpful, but more recent evidence suggests that it does not help. ...Read more

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Advise possible options to control parkinson disease?

Advise possible options to control parkinson disease?

Many are available: There are numerous drugs and treatments available. Consult with a neurologist to review your medical condition and get started on the correct road to control. ...Read more

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What are the medicine prescribed for parkinson disease?

Complicated: With the earliest symptoms, best approach is Dopamine agonist (mirapex, requip), later l-dopa, which remains fundamental, and maybe Azilect for potential protection. As the l-dopa becomes less efficacious, comtan, (entacapone) and even later combinations of all of the above, and if inadequate, use of deep brain stimulation. ...Read more

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Why in parkinson disease symptoms start asymmetrical ly?

Why in parkinson disease symptoms start asymmetrical ly?

Parkinson's: Parkinson's disease is a degenerative disease of the basal ganglia. As a degenerative disease, different areas of the brain die at different times which causes asymmetry of symptoms. ...Read more

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What are the symptoms of early or mild parkinson disease?

What are the symptoms of early or mild parkinson disease?

Slow progression: These symptoms typically involve resting tremor, slowness of body movements & rigidity of muscles & posture. They always begin on one side, then effect the midline (face, voice & balance, & finally do spread to involve the other side. Early pre-motor symptoms include: rbd (acting out dreams while sleeping), anosmia (loss of smell), constipation & depression. Also, slow mental clarity/st memory. ...Read more

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Can you suggest some good medicines for parkinson disease?

Parkinson Disease: There are a number of medications available for Parkinson disease but see which might be best for the patient you need to have a consultation with a neurologist who deals with this disorder - this physician can best assess which would be the best medication. ...Read more

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What are the typical symptoms of having parkinson disease?

What are the typical symptoms of having parkinson disease?

Dx of Parkinson's: Usually onset of sx's in late 50-60's in patients.They develope a resting pin- rolling tremor, masked facies, rigidity and slowing down of movements. They may also have postural instability and gait difficulties. Pls see an neurologist to be sure the condition is not "parkinsonism"related to medication, possible normopressure hydrocephalus or a stroke or brain mass. ...Read more

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How does parkinson disease affect your body's gait and posture?

Slows gait: Parkinson's slows movements and makes steps smaller. There are also balance difficulties and increased falls. Posture is often bent forward though there is a tendency to fall backwards known as retropulsion. These problems can be mild early on in the illness but can be debilitating if you have had the disease for a number of years. ...Read more

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Interested to know how does parkinson disease affect daily living?

Interested to know how does parkinson disease affect daily living?

Varies: This may vary depending on the severity of the parkinson's disease and also the response to medications.There are some who may have a minor tremor that is well controlled by medications.There are some that may have severe on/off problems that are debilitating and affect daily living.There are new surgical techniques(deep brain stimulation) that have a lot of promise in alleviating symptoms. ...Read more

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What are simple remedies for parkinson disease (including vastu remedies) ?

What are simple remedies for parkinson disease (including vastu remedies) ?

No remedies (cures): Parkinson's disease is unfortunately a progressive neurological disorder for which there is no remedy or cure at this time. However, there are many options for treatment, and with proper management of medications, exercise and other treatments patients can often do well for many years. ...Read more

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Can you tell me how parkinson disease affects normal homestasis of the body?

Can you tell me how parkinson disease affects normal homestasis of the body?

Parkinson Disease: Parkinson Disease is a disorder of the brain affecting mostly muscle control and cognition - it does not normally affect homeostatis of the body until the very late stages of the disease. ...Read more