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Doctor insights on: Parkinson's Disease

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Is parkinson’s disease hereditary?

Yes: Although the causes are multifactorial and sometimes poorly understood, there is a hereditary component. Keep in mind, that even though a parent may have it, it does not mean that it will be necessarily passed on. The tendency, however, may be there. ...Read more

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Can toxic substances cause parkinson’s disease?

Can toxic substances cause parkinson’s disease?

Parkinsonism: Yes. There is evidence that certain chemicals and pesticides can cause parkinsonism. We are now experiencing an epidemic of parkinsonism but it is not clear why this is happening. ...Read more

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Why can t healthy dopaminergic neurons be moved into the area of parkinson s affected neurons to treat parkinson s disease ?

Why can t healthy dopaminergic neurons be moved into the area of parkinson s affected neurons to treat parkinson s disease ?

Not so simple: Most of the dopaminergic neurons end in the substantia nigra of the midbrain, originating in various deep brain structures. These nerves are already affected by the disease. Unaffected nerves of course still remain but remain connected to brainstem. So outside nerve cells (from another source like stem cells are needed) nerves don't like to be moved around anyway, because they often die. ...Read more

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Can dysarthria due to parkinsons' s disease be cured?

Can dysarthria due to parkinsons' s disease be cured?

Control perhaps: Parkinson's disease is a progressive disorder, which responds to several medicines, but cannot be cured at this time. The speech problems may respond to medication adjustments, and perhaps benefit if deep brain stimulation is used. Sometimes speech therapy might work. ...Read more

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How long is safe to take gabapentin for rls? I´m afraid the long term use can cause parkinson´s disease... Is it possible to happen?

How long is safe to take gabapentin for rls? I´m afraid the long term use can cause parkinson´s disease... Is it possible to happen?

Safety: Gabapentin has been around since early 1970s and used for lots of conditions into the very high doses. Typically no causative issues with degenerative problems like parkinsons. With that being said, it does have side effects. With any medications you have weigh benefit vs. Risk. For RLS doses, typically side effects are minimal. Have treated people upwards of 10 years with Gabapentin ... ...Read more

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What are the causes of parkinson disease?

What are the causes of parkinson disease?

Causes of PD: Parkinson's disease involves depletion of a neurotransmitter in the part of the brain called the substantia nigra. The precise mechanisms of neurodegeneration in pd are unknown. There is believed to be an interaction between genetic and environmental factors, abnormalities in protein processing, oxidative stress, mitochondrial dysfunction, and others. ...Read more

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What are some meds for parkinson disease?

What are some meds for parkinson disease?

Numerous ITEMS: We have the anti-cholinergics like artane, but not used much these days, Dopamine agonists such as mirapex, requip, Neupro (rotigotine) patch. L-dopa with or without carbi-dopa, and maybe later entacapone. Azilect may be neuroprotective. The dbs unit could provide surgical support. ...Read more

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How does parkinson disease affect the body?

How does parkinson disease affect the body?

Many possibilities: Physical symptoms: resting tremor, slow movements, rigidity (stiffness) of muscles & posture. Causing slow walking, masked face, decreased blink rate, softer/mumbled speech, poor hand agility, small handwriting, potential falls & injury. Non-physical symptoms: cognitive decline, hallucinations/delusions, anxiety/depression, insomnia, sleepiness/fatigue, constipation, low bp, erectile dysfunction. ...Read more

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Is there a way to cure parkinson disease naturally?

Is there a way to cure parkinson disease naturally?

No cure: There is no cure for parkinson disease. There are many good medications, and exercise helps as well. There is nothing "natural" that has been shown to be helpful. Previously it was thought that coq10 was helpful, but more recent evidence suggests that it does not help. ...Read more

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