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Doctor insights on: Parkinson's Diease

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What distinguishes Parkinson's disease from alzheimer's disease?

What distinguishes Parkinson's disease from alzheimer's disease?

Many things.: Parkinson's Disease will present with physical symptoms such as shakiness, stiffness of the limbs causing a shuffling gait, lack of facial expression causing a mask-like face and the dementia may occur later while Alzheimer's dementia starts with gradual memory problems which begin to get worse in a few years and maybe accompanied with paranoid delusions. ...Read more

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How is Parkinson's disease diagnosed?

How is Parkinson's disease diagnosed?

History and exam: Parkinson's is usually diagnosed based upon it having very characteristic symptoms and exam findings - namely asymmetric (i.e. Usually starts on one side) tremor at rest, slowness of movements (bradykinesia), and stiffness (rigidity). There are some nuclear medicine tests that show the pathology of pd fairly reliably, but they are fairly new and considered experimental by most insurers. ...Read more

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Is parkinson’s disease hereditary?

Yes: Although the causes are multifactorial and sometimes poorly understood, there is a hereditary component. Keep in mind, that even though a parent may have it, it does not mean that it will be necessarily passed on. The tendency, however, may be there. ...Read more

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How is Parkinson's disease inherited?

How is Parkinson's disease inherited?

Mostly not inherited: The vast majority of people with parkinson's seem to get it sporadically, that is without any clear inheritance from family. That being said, we've found around 12 genetic variants that seem to greatly increase the risk of developing pd in some families. Some of them are recessive (rarely crops up), and some are dominant (50% chance of getting it from 1 affected parent). ...Read more

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Is Parkinson's disease hereditary?

Is Parkinson's disease hereditary?

A bit: There are some hereditary factors but they are seemingly minor. If you have a first-degree relative with parkinson’s disease you are more likely to get it, but the risk is small (< 5 % according to mayo clinic reports). It can run very strongly in some families in rare situations of abnormalities of alpha-synuclein synthesis or protein disposal problems. ...Read more

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Is Parkinson's disease hereditary?

Is Parkinson's disease hereditary?

Sometimes: Parkinson disease is the most common cause of parkinsonism, a symptomatic triad of tremor, muscular rigidity, and slow movement. Most of parkinson disease is caused by contributions of multiple genes, no one of which is necessary nor sufficient, aided by poorly defined environmental factors. About seven types of parkinson disease are inherited in an autosomal dominant or recessive pattern. ...Read more

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Is Parkinson's disease hereditary?

Is Parkinson's disease hereditary?

It can be, yes: As a general rule, the younger the age of onset (<45yo is early onset), & the more affected relatives (especially close ones), then the more likely it is genetic & the higher the risk to blood relatives. Average age of pd onset is 58. The older you are @ disease onset, the less likely it is genetically inheritable. Look @ this link for help on genetics: http://www.Ncbi.Nlm.Nih.Gov/books/nbk1223/. ...Read more

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Dr. Alan Ali Dr. Ali
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What is Parkinson's disease?

Dr. Alan Ali Dr. Ali
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What is Parkinson's disease?

Parkinson: Rigidity such as stiff neck, tremors, and slow movements are part of parkinson. It involves the part of the midbrain called Substantia nigra. ...Read more

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What sort of disease is creutzfeldt-jacob disease (c.J.D.)?

What sort of disease is creutzfeldt-jacob disease (c.J.D.)?

A prion disease: Cjd is caused by infection/exposure to an abnormal form of the prion protein (pp). The abnormal form of pp is a completely bent out of shape version of the normal pp . This abnormal shape is very hard for the protein to change to spontaneously, but this can happen (1 in a million people). Once changed the abnormal pp changes other pp's and so on as the disease rapidly spreads/kills the brain. ...Read more

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Is Parkinson's disease preventable?

Is Parkinson's disease preventable?

Parkinson's disease: No. Parkinson's disease (pd) cannot be prevented. It appears a genetic predisposition added to environmental exposure predisposes to the development pd. Repetitive head trauma may increase risk of pd. Caffeine and smoking may reduce the incidence of pd (not recommended for prevention). Exercise and active lifestyle may offer benefit in patients with the disease but not shown to prevent onset. ...Read more

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What's Parkinson's desease?

What's Parkinson's desease?

Chronic brain : It is a chronic degenerative disease of the brain that results in loss of fine control of the muscles, loss of the ability to walk and eventually loss of any purposeful movement. ...Read more

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Hi. What is wilson disease diseas?

Hi. What is wilson disease diseas?

Copper: Wilson's disease is a disorder of copper metabolism causing too much copper in the blood and tissues. ...Read more

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What is pseudo Parkinson's disease?

Not Parkinson's: Parkinson's disease is a disorder of the brain characterized by slowness of movement, rigidity of muscles and is caused by a deficiency of Dopamine in the brain. Many drugs such as the anti-psychotics can cause a parkinson's-like picture, as can some severe infections and metabolic disorders. I believe the term is more of a lay term than what is truly found in medical books. ...Read more

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What is familial creutzfeldt-jakob disease (cjd)?

What is familial creutzfeldt-jakob disease (cjd)?

Hereditary CJD: In hereditary cjd, the person has a family history of the disease and/or tests positive for a genetic mutation associated with cjd. About 5 to 10 percent of cases of cjd in the United States are hereditary. ...Read more

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Can wilsons disease mimic parkinsons?

Can wilsons disease mimic parkinsons?

Yes: Parkinson-like symptoms can be an initial manifestation of Wilson's disease. Wilson's disease usually occurs in younger people, however. If there is any confusion in diagnosis, Wilson's disease can usually be diagnosed through a combination of blood tests, urine tests, and/or an eye exam. Hope this helps. ...Read more

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How is Parkinson's disease treated?

How is Parkinson's disease treated?

Good Rx available!!: Dopamine meds are mainstay of treatment. Modern therapy recommends longer lasting, milder potency meds first: Azilect (mao-b selective inhibitor) & Dopamine agonists (requip xl/mirapex er/neupro). After they've been maximized & stronger meds are needed to adequately manage symptoms, then sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together) are begun. Tailor rx with side effects in mind for each person. ...Read more

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Parkinson's disease/alzheimer's disease, what's the difference?

Parkinson's disease/alzheimer's disease, what's the difference?

Different dementias: Alzheimer' s disease is marked by decline in cognitive function because of brain changes that affect memory/executive function.Parkinson's disease is marked by problems with motor function because of nervecell loss in different part of the brain. In some cases cognitive changes occur as wellI. Cause of both are not known but the greatest risk factor is old age and some forms that run in families ...Read more

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Is alzheimer's disease inherited?

Is alzheimer's disease inherited?

Likely yes: If there is a strong history of alzheimer's disease in the family like grandparents, parents, uncles, aunts, brothers or sisters, then you could be at risk of developing it. ...Read more

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