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Doctor insights on: Paraventricular White Matter Disease

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What is chronic white matter ischemic disease?

What is chronic white matter ischemic disease?

Lack of blood deep : In the brain. This condition is most commonly seen in individuals with one or all of the following:
1. Hypertension
2. Diabetes
3. Hyperlipidemia (high cholesterol)
4. Cigarette smoking
5. Family history of stroke

Of course there are others but these are most important. Please meet with your neurologist to discuss why and what you can do to help your situation. Good luck and well wishes. ...Read more

White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


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Mild supratentorial white matter disease--what is this?

Mild supratentorial white matter disease--what is this?

Maybe of no signif.: White matter lesions may be caused from a host of circumstances, such as migraine, prior head or neck trauma, hardening of the arteries, inflammation like multiple sclerosis, prior small strokes, effect of some medications such as methotrexate, and is not specific. The location of your concern maybe actually a chronic, lifelong issue. Consult your doctor. ...Read more

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I had an MRI that showed minimal white matter disease that was not addressed. Now im having signs of MS.?

I had an MRI that showed minimal white matter disease that was not addressed. Now im having signs of MS.?

Get re-evaluated: The MRI may well be nonspecific, and the result of migraine, old head trauma, smoking, etc. But if you now have neurological symptoms, and "signs", this needs to be evaluated fully and diagnosed, so that the appropriate cause can be treated. This may not necessarily be MS, and certainly best to find out. ...Read more

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I had an MRI and was diagnosed with white matter changes to my left external capsule(not sure where that is) Is there a way to slow this disease down?

I had an MRI and was diagnosed with white matter changes to my left external capsule(not sure where that is) Is there a way to slow this disease down?

White matter changes: Without understanding what prompted the ordering of the MRI, not the specific aspects and findings of the MRI (location, sequence etc) it is difficult to determine what these findings on their own mean. Since you have clearly had a previous health care provider interaction, suggest you speak to that provider to further discuss the relevance of these findings. ...Read more

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What is chronic periventricular white matter microvascular ischemic disease?

What is chronic periventricular white matter microvascular ischemic disease?

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more

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I have white matter disease and the neurologist didn't really tell me that it would cause cognitive issues. Will these issues get better?

I have white matter disease and the neurologist didn't really tell me that it would cause cognitive issues. Will these issues get better?

Maybe...: Really depends on the location and the number of white matter lesions. In demyelinating disorders such as multiple sclerosis if having an increase lesion burden, cognitive dysfunction will occur. Otherwise, the number and location is important to determine whether there'll be any memory or cognitive issues. ...Read more

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I asked earlier about MS and white matter disease. I have had an MRI (2) actually. Shows lesions. "Stroke" in october. But wad told not a stroke?

I asked earlier about MS and white matter disease. I have had an MRI (2) actually. Shows lesions. "Stroke" in october. But wad told not a stroke?

MRI WHITE LESIONS: Mris are very sensitive at identifying any change in anatomy. Some lesions can look like the beginning of ms, but not actually turn into the disease. High blood pressure and trauma can cause lesions they look like ms or small strokes. Serial examinations are sometimes required to figure out if the findings improve, stay the same, or increase. ...Read more

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I have MS symptoms, balance, memory, speech thinking problems. Had an unfounded stroke as well. Dr says only white matter disease. I feel like it's ms.?

I have MS symptoms, balance, memory, speech thinking problems. Had an unfounded stroke as well. Dr says only white matter disease. I feel like it's ms.?

MS diagnosis: MS is not an easy diagnosis to make. There are often numerous brain lesions and abnormalities in the CSF, which is obtained by spinal tap.

Think of having symptoms, but they are not necessarily MS symptoms. Sometimes the spinal tap or MRI tests done over a long time help answer your question. ...Read more

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MRI done showed brain lesion... If it were white matter disease would they have known by this MRI?

MRI done showed brain lesion... If it were white matter disease would they have known by this MRI?

Likely: MRI is the study of choice for evaluating the soft tissues of the brain. Sometimes IV contrast is used to also evaluate the blood vessels of the brain. ...Read more

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My husband has been diagnosed with severe white matter brain disease. What is that and what does it mean? He is recovering from a stroke.

My husband has been diagnosed with severe white matter brain disease.  What is that and what does it mean?  He is recovering from a stroke.

"White matter": I agree with dr. Kumar. "White matter" refers to the nerve fibers that facilitate communication between nerve cells -- along with myelin, a fatty sheath that covers the them. White matter is below the surface layer of the brain, and can be followed all the way down the spinal cord. Strokes can injure these areas; some people have cognitive changes as well as physical symptoms afterwards. ...Read more

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I had an MRI done an it says mild patchy white matter hyperintensity of the pons is stable likely representing microangiopathic disease mean what doe?

I had an MRI done an it says mild patchy white matter hyperintensity of the pons is stable likely representing microangiopathic disease mean what doe?

Radiology talk: The reader of the imaging is suggesting that atherosclerosis is the cause of the white matter changes. These items can be nonspecific, and might better relate to prior migraines or cigarette smoking, or even prior head injury. ...Read more

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Can a brain MRI detect nonspecific supratentorial white matter disease?

Can a brain MRI detect nonspecific supratentorial white matter disease?

Yes: Nonspecific white matter disease may be seen in individuals with migraine headache, can be post infectious or can be a result of hypertension and high cholesterol. At times MRI with administration of contrast is recommended to better characterize these lesions. ...Read more

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MRI showed moderate supratenatorial white matter disease suspicious of demyelinating process. Multiple nodular foci periventricular Could you explain?

Concern for MS, But: Phyllis, talk to the doctor who ordered the MRI, since he/she can interpret the MRI in the context of the symptoms that brought you to the clinic. In some cases, periventricular white matter lesions are the result of migraines, old head trauma, neuron migration issues, or MS. It is hard to know from just a description of the MRI which is the cause. Good Luck and Stay Healthy! ...Read more

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I'm 42 female with anxiety and was trying to rule out everything. Had a brain MRI which shows minimal nonspecific white matter disease. Should I worry?

I'm 42 female with anxiety and was trying to rule out everything. Had a brain MRI which shows minimal nonspecific white matter disease. Should I worry?

Probably not: This is a fairly common aging related finding, usually nothing to worry about. It's significance, if any, can be assessed by your doctor in the context of your entire clinical picture. Possibly follow up MRI in 6 months or so to confirm stability. ...Read more

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Could multiple sclerosis be considered to be a white matter disease due to atrophy of the brain, like other well-known white matter diseases?

Could multiple sclerosis be considered to be a white matter disease due to atrophy of the brain, like other well-known white matter diseases?

Not exactly as said: Multiple Sclerosis is considered to be a neurodegenerative disease of the white matter but it's not DUE TO atrophy rather it occurs as a result of an autoimmune attack by the body of the white matter tracts. There's also ATROPHY of the brain (cortex mainly) resulting from the white matter disease & other factors. If you have more questions let me know at www.healthtap.com/drsaghafi ...Read more

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MRI white matter disease in bilateral cerebral hemisphere; this may be seen with moderate chronic ischaemia versus inflammation/demylination. Worried.

MRI white matter disease in bilateral cerebral hemisphere; this may be seen with moderate chronic ischaemia versus inflammation/demylination. Worried.

Worried ?: I suggest you contact your neurologist right away to explain the findings. The idea is to find out what's going on so that you don't have to worry!. You might consider consulting with one of us. That's what we do!

www.healthtap.com/drericweisman ...Read more

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Hello I had a car accident and my cat scan came up I have mild periventricular white matter disease. Can the car accident show pwm this after two day?

Hello I had a car accident and my cat scan came up I have mild periventricular white matter disease. Can the car accident show pwm this after two day?

Not due to accident: This is not due to your accident. YOu need to see a Neurologist. Potential causes of this include long-standing hypertension. ...Read more

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Can ischemic small vessel disease cause gliosis? How would ischemic small vessel disease be treated in a minimal area of white matter in the brain?

Can ischemic small vessel disease cause gliosis?  How would ischemic small vessel disease be treated in a minimal area of white matter in the brain?

Yes.: White matter changes frequently seen on brain MRI are the result of chronic small vessel ischemic disaease and it is the resulting small focus of gliosis that shows on the MRI imaging. Treating your underlying cardiovascular heath is key, not the MRI finding. ...Read more

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What disease would be indicated if a CT scan showed a reduction of grey and white matter in the brain?

What disease would be indicated if a CT scan showed a reduction of grey and white matter in the brain?

Long list. : See brain atrophy at rightdiagnosis. Com. Discuss concerns with your doctor and a neurologist. ...Read more

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My cat scan showed mild intracranial atrophy and mild supratentorial small vessel white matter disease?

My cat scan showed mild intracranial atrophy and mild supratentorial small vessel white matter disease?

See your doctor: These findings need to be put into perspective with respect to the symptoms which led to the decision to order the ct scan in the first place. In some, these could be consgtrued as normal findings, though 45 years old is young for these. ...Read more

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I recently had an MRI of the brain. The results whereas follows mild atrophy and mild periventricular white matter ischemic small vessel disease. Wh?

I recently had an MRI of the brain. The results whereas follows mild atrophy and mild periventricular white matter ischemic small vessel disease.  Wh?

Arteriosclerosis : You are taking hydrocodone, tramadol & Lyrica (pregabalin) for nagging pain plus Ambien for sleep and Buspirone for anxiety. Combination is heavy stuff. Had migraine but not anymore? Microvascular disease is the blockage of tiny vessels-arteriosclerosis. These can happen in heart & kidney as well. Check your lipid profile and possible use of statin. For headache & reevaluation of all your meds see neurologist. ...Read more

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81 year old mother, CT periventricular deep white matter changes and moderate small vessel iscjaemic disease. Serious?

81 year old mother, CT periventricular deep white matter changes and moderate small vessel iscjaemic disease. Serious?

CT changes: These changes are very common for any person at this age. She needs to eat healthy, exercise regularly and have her blood pressure, cholesterol and blood sugar under good control. ...Read more

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Was told I have white matter disease. I feel like drs aren't listening. I have had problems with numbness in face, legs, feet. Alien hand, " stroke"?

Was told I have white matter disease. I feel like drs aren't listening. I have had problems with numbness in face, legs, feet. Alien hand, " stroke"?

Yes. It could be.: Strokes can involve white matter disease, so the symptoms you describe may be from a stroke. If it hasn't been worked up, it should be. ...Read more

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Ordered CT scan brain MRI for lumbar spine after fall stairs lft leg has been numb 3yr prior to stairs spine not bad brain chronic microvascular ishemic white matter disease ms? Autoimmune?

Ordered CT scan brain MRI for lumbar spine after fall stairs lft leg has been numb 3yr prior to stairs spine not bad brain chronic microvascular ishemic white matter disease ms? Autoimmune?

Ischemic Brain: Not likely. At your age, the vascualr ischemia is more apt to be due to chronic high blood pressure or diabetes. It is important to follow up on this with your doctor to avoid small lesions called "lacunar" infarcts. Often, medication can be prescribed which will improve your micro vascualr integrity and avoid further damage. ...Read more

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Our daughter has elevated aldolase and lph. She has a complex chronic pain disorder. What should be looked at? Eeg is normal. Mri shows white matter.

Our daughter has elevated aldolase and lph. She has a complex chronic pain disorder. What should be looked at? Eeg is normal. Mri shows white matter.

Growing pains?: If your daughter is nearing puberty the laboratory studies just indicated hormone effects and growth effects. Mri changes need to be evaluated by a good specialist, but may be normal variant. The chronic pain disorder is becoming a major epidemic now among young people. Be careful not to over react or over treat. She needs counseling to help with pain management. ...Read more