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Doctor insights on: Paraproteinemia Symptoms

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What causes paraproteinemia?

What causes paraproteinemia?

Plasma cells: Paraproteins are abnormally produced immunoglobulins or immunoglobulin fractions made by overproductive and possibly malignant clones of plasma cells. This needs evaluation by a hematologist to determine if this is benign or malignant (cancer). ...Read more

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What are the consequences of paraproteinemia?

What are the consequences of paraproteinemia?

Varied: We have 3 entities which cause paraprotein production. The most benign is called MGUS which is often benign and the other two are Smoldering Myeloma and the most serious is called Multiple myeloma. You need to have your doctor explalin which of these conditions he/she thinks is causing this paraproteinemia. ...Read more

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What causes monoclonal paraproteinemia?

What causes monoclonal paraproteinemia?

Excess of Plasma cel: Plasma cells in our bone marrow make antibodies. Sometimes they become overly active/reactive and produce abnormal proteins called paraproteins. Most such protein production is benign and not uncommon in older folks. Sometimes it is excessive (more than 1gram/day) then we get concerned about a condition called multiple myeloma (paraproteins over 3 grams). ...Read more

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How are benign and malignant paraproteinemia different?

How are benign and malignant paraproteinemia different?

Different causes: Malignant paraproteinemia is a harmful presence of a single kind of antibody, made by a known malignancy such as lymphoma or myeloma. Benign paraproteinemia is a harmful presence of a single kind of antibody in someone who has no such malignancy. It is presumably due to a benign clonal expansion of one type of lymphocyte. ...Read more

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What is the difference in benign and malignant paraproteinemia?

What is the difference in benign and malignant paraproteinemia?

Abnormal Proteins/My: Paraproteins are abnormal proteins which are often produced by Cancer cells unless proven otherwise. So it requires detailed testing looking for cancerous cell called Plasma cells in the bone marrow. There is one variant which may behave beningnly and is called monoclonal gammopathy of undetermined significance (MGUS). But some of the patients with MGUS do develop multiple myeloma, causing paraprot ...Read more

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Is monoclonal paraproteinemia the same thing as myeloma?

Yes in most ways: Myeloma is one of the differential diagnosis, the other condition is called mgus ...Read more

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Is there a cure medication to completely remove eradicate paraproteinemia from my blood stream its at 1.5 level im told. Or is it incurable?

Is there a cure medication to completely remove eradicate paraproteinemia from my blood stream its at 1.5 level im told. Or is it incurable?

Hematologist: You need to consult a hematologist/oncologist for treatment. There are effective treatments using chemotherapy and the using person's own stem cells to correct the defect. Consult this site for info.

http://www. Mayoclinic. Org/diseases-conditions/multiple-myeloma/basics/definition/con-20026607 ...Read more

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My 81 yr old father is diagnosed with monoclon paraproteinemia, what does that mean and what are the causes?

My 81 yr old father is diagnosed with monoclon paraproteinemia, what does that mean and what are the causes?

MGUS: Monoclonal gammopathy of unknown significance (mgus) is a very insidious disease. I do not believe that it worsens his prognosis or lifespan significantly. ...Read more

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Serum -tiny IgM kappa monoclonal protein b2 region, urine - tiny IgM k paraproteinemia in gamma region. Was a mistake made or is lab normal?

Serum -tiny IgM kappa monoclonal protein b2 region, urine - tiny IgM k paraproteinemia in gamma region. Was a mistake made or is lab normal?

Monoclonal: multiple myeloma (g>a>m>e, d)
•primary macroglobulinemia (waldenstrøm’s, igm)
•monoclonal gammopathy of undetermined significance (mgus) (converts at 2% per year to myeloma)
•miscellaneous conditions
• (converts at 2% per year to myeloma)

these all have to be thought of by the hematologist. ...Read more

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What are the symtoms of paraprotienenemia?

What are the symtoms of paraprotienenemia?

None, but...: The presence of a monoclonal (para)protein in the blood (on spep) or urine (on upep) with or without an abnormal free light chain (flc) k/l ratio is a laboratory finding. This may be mgus (monoclonal gammopathy of unknown significance), myeloma, lymphoma, cll, etc. A few classic symptoms of myeloma are crab -- hypercalcemia, renal insufficiency, anemia, bone (lytic) lesions. Other sx possible... ...Read more

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It’s not serious, so I can just ignore the symptoms, can’t i?

It’s not serious, so I can just ignore the symptoms, can’t i?

Please more specific: Please be more specific in asking your question. ...Read more

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Please explain what are some symptoms of a broken rib (s)?

Please explain what are some symptoms of a broken rib (s)?

Pain with inhalation: The most classic symptom is rib pain (often severe) with a deep breath. If the fracture is severe the rib may float independently from the other ribs. ...Read more

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How can my wife relieve the symptoms of I b s while pregnant?

How can my wife relieve the symptoms of I b s while pregnant?

Medications: There are several ibs medications that can be used in pregnancy. Discuss with your GI specialist and obgyn. ...Read more

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What is the number of deaths per year in the u.S. For people with symptoms of aids?

What is the number of deaths per year in the u.S. For people with symptoms of aids?

Number of AIDS death: Since beginning of epidemic: 617, 025,
including more than 16, 000 in 2008

http://www. Kff. Org/hivaids/upload/3029-12.Pdf. ...Read more

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What are the possibilities of malignancy if you just happen to be 50 years old in the u.S. But with no symptoms?

What are the possibilities of malignancy if you just happen to be 50 years old in the u.S. But with no symptoms?

Breast/colon/cervix: All malignancies are without symptoms at onset. The malignancies we can detect early enough to prevent mortality are colon, breast and cervical cancer. 50 year old should be in some program of prevention and early detection for these. ...Read more

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Please suggest the best OTC medicine (s) for sinus symptoms management (esp. The headache) and can be used regularly.

Please suggest the best OTC medicine (s) for sinus symptoms management (esp. The headache) and can be used regularly.

OTC meds for Sunuses: Pseduephedrine (Sudafed) is the main decongestant sold OTC, but due to its potential for abuse, it is now stored behind the shelf and u need to ask for it. It can cause increased heart rate and insomnia.
u can use nasal sprays to decongest while avoiding the insomnia caused by oral decongestants. Anti allergy meds
can be used if they are adding to the congestion otherwise u can skip these ...Read more

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I always miss my second 12 hour dose of doxyciline for a s.t.d. I was starting to not see symptoms but now im seeing them again I have five pills left?

I always miss my second 12 hour dose of doxyciline for a s.t.d. I was starting to not see symptoms but now im seeing them again I have five pills left?

Restart meds: Please see your doctor. If this is for chlamydia, you can take a one time 1 gram dose of azithromycin instead of the doxycycline so that you do not miss doses. If it is for PID you may need the Doxy.
Also you shouldn’t have sex for 10 days after starting treatment to prevent sending the infection back and forth with your partner ...Read more