Doctor insights on:
Removal of primary:
Complete removal of the tumor causing the paraneoplastic syndrome should help. However, the lesions may not be reversible. See this site for more info.
http://www. Mayoclinic. Org/diseases-conditions/paraneoplastic-syndromes/basics/definition/CON-20028459 ...Read more
Depends on type: There r many paraneoplastic neurologic syndromes, each associated with specific types of cancers. Thus, there's no generic answer to ur question. Paraneoplastic lymphomas, 4 instance, can produce specific antibodies which can b detected by blood tests or lumbar puncture, depending. The best "test"? A thorough history & physical by some1 knowledgeable (oncologist, neurologist) who can guide u more ...Read more
Have had symptoms of paraneoplastic neurological syndrome for 3 years. What tests should I go for?
If this is your own: Self-diagnosis, then the only tests you need at this time is a proper history and evaluation by a competent clinician. That individual will then explain if tests are indicated and what they will be. ...Read more
What is the like hood to have a paraneoplastic neurology syndrome if the paraneoplastic panel (anti body) blood test is negative?
Need more info: It would be worthwhile to discuss this with an oncologist that your family physician can suggest. ...Read more
Well it can.: Paraneoplastic syndromes of the nervous system usually can have varying symptoms of all kinds depending on the body part being injured. One of the things that can be injured is known as Dysautonomia. This means injury to the body functions that are involuntary that includes heart rate. ...Read more
Autonomic neuropathy symptoms for 21 months. Anti hu tested negative. Could this be a paraneoplastic neurological syndrome? Any advice, thankyou.
Symptoms 21 months:
You MUST return to the doctor (s) who have cared for you!
Hope all goes well - please keep me posted. ...Read more
If PET/CT comes back negative while looking for occult cancer (paraneoplastic neurological sympts) can I relax, symptoms ongoing 2 years. Thanks you.
Is it possible to have paraneoplastic neurological symptoms (not LEMS) from SCLC with no evidence of LC on CT scan 1 year after symptoms started?
Autonomic neuropathy sympts for 21mths. Anti hu tested neg. Could this be a paraneoplastic neurological syndrome? My GP says don't worry PNS rare. Ideas
Autonomic neuropathy: Occurs in women typically with onset in the 4th or 5th decade. First confirm you have it (see a neurologist and have an EMG-NCS done. If the diagnosis is in question thermal testing and a tilt table test can clarify matters. Read about POTS and its many causes ...Read more
Unusual neurological symptoms, Paraneoplastic Panel was done at my request, neuro doesn’t suspect it at all based on presentation, waiting for results. How common are FALSE POSITIVE results?
Please repost: Your question is meaningless without a description of your “unusual” neurological symptoms. The significance of any testing is determined in large part by the pre-test probability of actually having the condition tested for. Furthermore, paraneoplastic syndromes of the nervous system are EXTREMELY rare. I think you can safely find something else to worry about. ...Read more
What negative results in paraneoplastic serum panel mean? What the like hood to have the neurology syndrome with negative results?
Based on H&P: A para neoplastic syndrome is based on history and exam. Do not base the absence of a para neoplastic syndrome on a negative serum panel. I rarely get the panel because you treat the person and the disease not the test. Hope this helps. ...Read more
Many: Neurologic paraneoplastic syndromes are caused by an abnormal immune response to the tumor, which makes the body accidentally attack its own nervous tissue. Muscle weakness, stiff limbs, dizziness, coordination problems, vision problems, confusion, difficulty swallowing, memory problems and numbness are some of the many possible symptoms. ...Read more
What is the best indicator of cancer: "tumor markers" or "paraneoplastic autoantibodies"? I have signs of cancer and neurological autoimmunity.
Neither: There are only a handful of very rare circumstances where a "tumor marker" blood test can prove that someone has a cancer. This is because many tumor markers can be elevated by other causes. Paraneoplastic autoantibodies do not diagnose cancer but are called that when a patient with a known cancer has autoantibodies without another known cause. ...Read more
Neurology question concerning a abnormal paraneoplastic panel I was told that my panel had abnormalities in it and that I should have a chest CT scan done and a lambert eaton test and a never conduction study as well. I went to the neurologist because my
Lambert-eaton syndrome is a neuromuscular disorder associated with abnormal antibodies to what are called voltage gated calcium channels. These are channels in the membrane of the nerve part of the nerve-muscle junction. When a signal travels along the nerve to a muscle cell the tip of the nerve makes contact with the muscle cell and forms what is called a neuro-muscular junction. A substance called acetylcholine (a neuro-transmitter) is released into the neuromuscular junction and attaches to receptors on the muscle. The acetylcholine then causes potential changes in the membrane and the muscle cell is activated. The role of the voltage gated channels are to allow for the release of the acetylcholine. If abnormal antibodies are attached to the channels, the acetylcholine can't be released. This results in les. Les is sometimes confused with myasthenia gravis, a condition in which other antibodies are attacking the receptor sites at the nerve muscle junction. Both conditions can cause muscle weakness because both affect the function of the nerve muscle junction. The vgcc (voltage gated calcium channel) antibodies are often seen in people with certain types of lung and thymus tumors sometimes long before the tumor is actually found. A chest ct scan would be done to look for a tumor. An EMG and nerve conduction test would help distinguish between les and mg.
There is an association between autoimmune disorders and les not related to small cell tumors of the lung. There are treatments available. It is good that you don't have ms. Good luck to you. ...Read more
Neurologist or oncologist for paraneoplastic neurological syndrome? Maybe sclc? -smoked 10yr. Now: dysesthesias, fatigue, cold/heat intolerant, no hunger.
See neurologist: Neurologists deal with these things. There are blood tests which can some times help figure these things out. ...Read more
First, 4 years of college, then 4 years of medical school...Then a year of internship and then about 3-5 years of residency/fellowship.
It takes a lot of money and time and dedication...I am pleased that you are interested, but go talk to a neurologist first before you make a decision... ...Read more
Migraine: There are two kinds of therapies: abortive- design to alleviate the pain during an attack and preventive- designed to reduce frequency and intensity of migraine. They are usually triggered by inadequate diet, poor sleep, stress or certain medications. Check with your doctor to find our what could be your best medication as it may vary for person to person based on their history. ...Read more
Neurosyphilis: Neurosyphilis is an infection of brain/spinal cord caused by untreated syphilis (caused by the bacteria treponema palladum). It is a late complication. It may be asymptomatic or manifest with different neurological problems (e.g. Abnormal walking, poor reflexes, dementia, etc...) a neurological exam (including imaging) and blood tests for syphilis are done. Treatment is usually with penicillin. ...Read more
See your doctor: The best thing to do is to first talk to your primary care physician. You will be examined and if your doctor thinks you need tests or need to be seen by a neurologist, those tests/consults will be ordered. ...Read more
Must believe so: Nerves and brain tissue do not repair in the manner of other tissues. However, they can repair or accommodate to injury in remarkable ways. There must always be hope that recovery will occur. There should also be realistic approach to doing the best with what we have. Patients who are brain injured, paralyzed, epileptic, memory loss, have multiple sclerosis or parkinsonism can live well. ...Read more