Doctor insights on:
Para Supranuclear Palsy
Different types: Supranuclear refers to loss of function due to a lack of high level cerebral control of a cranial nerve. E.G., in supranuclear gaze paresis there is difficulty voluntarily moving the eyes, but reflex eye movements are intact. Nuclear/ infranuclear refers to problems caused by damage to a cranial nerve nucleus or nerve itself. In this case voluntary & reflex movements would be impaired. ...Read more
...is a corruption of French "paralise" from Latinized Greek "paralysis." In the old days it meant any kind of persistent weakness. To this day Parkinson's disease is also called "paralysis agitans" which is a Latin translation of Dr. Parkinson's original name for it, the "shaking palsy." We've obviously reborrowed the full form "paralysis" into English as well; today ...Read more
Gaze palsy: Meaning, one can't look to the right or left. ...Read more
Good Rx Available!!!: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile. ...Read moreSee 2 more doctor answers
Tau protein D/O: No, tau protein deposits & neurofibrillary tangles in neurons cause the death of these cells. Because they are in some similar areas as parkinson's disease, psp can appear similar clinically, but there are clear differences. Treatment approaches are roughly the same with different areas needing most attention. Primarily balance/falls/injury, did inhibiting dementia & dysphagia/aspiration. ...Read moreSee 1 more doctor answer
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Supranuclear palsy is a rare brain condition that causes serious problems with walking, eye movements, and balance. The disorder develops slowly over time as the cells in parts of the brain that control movement are destroyed. Although there is no cure, there are ways ...Read more
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