Rated 5.0/5 based on 22 votes

Top
10
Doctor insights on: Para Supranuclear Palsy

Share
1

1
What is the difference between infranuclear and supranuclear paralysis?

What is the difference between infranuclear and supranuclear paralysis?

Different types: Supranuclear refers to loss of function due to a lack of high level cerebral control of a cranial nerve. E.G., in supranuclear gaze paresis there is difficulty voluntarily moving the eyes, but reflex eye movements are intact. Nuclear/ infranuclear refers to problems caused by damage to a cranial nerve nucleus or nerve itself. In this case voluntary & reflex movements would be impaired. ...Read more

Get help from a doctor now ›
Dr. Umesh Patel
Board Certified
36 years in practice
343K people helped
Get help from a real doctor now
Continue

Palsy (Definition)

...is a corruption of French "paralise" from Latinized Greek "paralysis." In the old days it meant any kind of persistent weakness. To this day Parkinson's disease is also called "paralysis agitans" which is a Latin translation of Dr. Parkinson's original name for it, the "shaking palsy." We've obviously reborrowed the full form "paralysis" into English as well; today ...Read more


2

2
What are the tests for supranuclear palsy?

Brain studies: This is a term reserved for conditions that affect the connection between nuclei controlling the eye movements with the centers in the brain usually in the frontal lobes. Inability to look up is a common finding. ...Read more

Get help from a doctor now ›
Dr. Umesh Patel
Board Certified
36 years in practice
343K people helped
Get help from a real doctor now
Continue
4

4
How can you treat progressive supranuclear palsy?

How can you treat progressive supranuclear palsy?

Good Rx Available!!!: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile. ...Read more

Get help from a doctor now ›
Dr. Umesh Patel
Board Certified
36 years in practice
343K people helped
Get help from a specialist now
Continue
5

5
How is progressive supranuclear palsy (psp) diagnosed?

How is progressive supranuclear palsy (psp) diagnosed?

Cannot look up: Similar to but worse prognosis than parkinson's disease sharing the rigidity and poverty of movements, inability to look up with head kept straight. ...Read more

Get help from a doctor now ›
6

6
What can cause progressive supranuclear palsy?

What can cause progressive supranuclear palsy?

Tau protein D/O: No, tau protein deposits & neurofibrillary tangles in neurons cause the death of these cells. Because they are in some similar areas as parkinson's disease, psp can appear similar clinically, but there are clear differences. Treatment approaches are roughly the same with different areas needing most attention. Primarily balance/falls/injury, did inhibiting dementia & dysphagia/aspiration. ...Read more

Get help from a doctor now ›
7

7
Is possible for progressive supranuclear palsy to be cured / get better?

Is possible for progressive supranuclear palsy to be cured / get better?

Good Rx, but no cure: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile. ...Read more

Get help from a doctor now ›
10

10
What is the prognosis for progressive supranuclear palsy?

Supranuclear palsy: Unfortunately, no known treatment other than supportive care for supranuclear palsy exists. The average person is in their 60's when diagnosed. Life expectancy averages 7 years after diagnosis. ...Read more

Get help from a doctor now ›
Dr. Justin ORourke
29 doctors shared insights

Supranuclear Palsy (Definition)

Supranuclear palsy is a rare brain condition that causes serious problems with walking, eye movements, and balance. The disorder develops slowly over time as the cells in parts of the brain that control movement are destroyed. Although there is no cure, there are ways ...Read more


Dr. William Singer
941 doctors shared insights

Paralysis (Definition)

A paralyzed limb cannot be voluntarily moved, and the term reflects leg involvement, paraplegia, full body, quadriplegia, and less than full, tetraplegia. Causes can be many, including stroke, trauma, ...Read more


Get more personalized answers directly from real doctors!

Get help from a real doctor now
Dr. Umesh Patel
Board Certified, Cardiology
36 years in practice
343K people helped
Continue
68,000 doctors available
Find us on Facebook